Konu "oxidative stress" için Fakülteler listeleme
Toplam kayıt 44, listelenen: 1-20
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8-Br-cADPR,a TRPM2 ion channel antagonist, inhibits renal ischemia-reperfusion injury
(Wiley, 2019)The transient receptor potential melastatin-2 (TRPM2) channel belongs to the transient receptor potential channel superfamily and is a cation channel permeable to Na+ and Ca (2+). The TRPM2 ion channel is expressed in the ... -
Altered thiol/disulfide homeostasis and ischemia-modified albumin levels in children with irritable bowel syndrome
(John Wiley and Sons Inc, 2021)Background: In this study, we assessed thiol/disulfide homeostasis (TDH) parameters and ischemia-modified albumin (IMA) levels in children with irritable bowel syndrome (IBS) compared with healthy children. Methods: Fifty-six ... -
Alzheimer hastalığında doublecortin-like kinaz-1 düzeyleri ve oksidan durumu
(Cukurova Univ, Fac Medicine, 2017)Purpose: Alzheimer disease (AD) is a progressive neurodegenerative disease that affects the neurons in various parts of the central nervous system. Recently discovered protein Doublecort like kinase-1 (DCLK-1) is one of ... -
Antioxidative, antiapoptotic, and proliferative effect of curcumin on liver regeneration after partial hepatectomy in rats
(Sage Publications Inc, 2015)The aim of the present study was to assess the influence of curcumin on liver regeneration after partial hepatectomy (PH) in rats. A total of 24 male Sprague Dawley rats were divided into three groups: sham-operated (SH), ... -
Association analyses of oxidative stress, aerobic capacity, daily physical activity, and body composition parameters in patients with mild to moderate COPD
(Tubitak Scientific & Technical Research Council Turkey, 2014)Background/aim: To investigate total oxidant and antioxidant status, maximal aerobic capacity, daily physical activity, pulmonary functions, and body composition changes, as well as the associations among these parameters, ... -
Association of coronary artery disease severity and disulphide/native thiol ratio
(Modestum Ltd, 2017)Objective: Oxidative stress is among the major components of cardiovascular disease pathogenesis. Thiols play a significant role in prevention of oxidative stress in the cell. The purpose of this study is to investigate ... -
Association of Thiol Disulfide Homeostasis with Childhood Asthma
(Georg Thieme Verlag Kg, 2016)The aim of this study is to evaluate the oxidative stress level in asthmatic children in terms of the disulfide/thiol ratio, to research the role the disulfide/thiol ratio plays in the pathogenesis of the malady, and to ... -
Caloric restriction and redox homeostasis in various regions of aging male rat brain: Is caloric restriction still worth trying even after early-adulthood? Redox homeostasis and caloric restriction in brain
(Wiley, 2019)Despite recent studies have shown that caloric restriction (CR) could improve some functional loss associated with brain aging, the biochemical effects of CR on brain aging are still not well understood on a quantifiable ... -
Cardioprotective effects of fish omega-3 fatty acids on doxorubicin-induced cardiotoxicity in rats
(Sage Publications Ltd, 2014)The aim of this study was to investigate the protective effects of fish omega-3 (n-3) fatty acids on doxorubicin (DOX)-induced acute cardiotoxicity. A total of 24 rats were divided into three groups: control, DOX-treated, ... -
Effect of hesperetin on inflammatory and oxidative status in trinitrobenzene sulfonic acid-induced experimental colitis model
(Cellular and Molecular Biology Association, 2018)In our study, the effect of hesperetin on inflammatory and oxidative status in trinitrobenzene sulfonic acid (TNBS)-induced experimental colitis model was investigated through different methods. Eighteen Wistar albino male ... -
Effect of Urtica Dioica against Doxorubicin-Induced Cardiotoxicity in Rats through Suppression of Histological Damage, Oxidative Stress and Lipid Peroxidation
(Modestum Ltd, 2016)Objective: Doxorubicin (DOX) is a highly effective anti-cancer drug with limited clinical use due to its serious cardiotoxicity. Urtica dioica L. seeds (UD), have been widely used in folk medicine, particularly in the ... -
Effects of combined administration of doxorubicin and chloroquine on lung pathology in mice with solid Ehrlich ascites carcinoma
(Taylor & Francis Ltd, 2022)Combined use of a chemotherapeutic agent and an autophagy inhibitor is a novel cancer treatment strategy. We investigated the effects of chloroquine (CQ) on lung pathology caused by both solid Ehrlich ascites carcinoma ... -
The Effects of Quercetin on Acute Lung Injury and Biomarkers of Inflammation and Oxidative Stress in the Rat Model of Sepsis
(Springer/Plenum Publishers, 2016)Experimental studies indicate that sepsis causes remote organ injury although the molecular mechanism has not been clearly defined. In this report, the role of oxidative damage, and inflammation on lung injury, following ... -
The effects of quercetin on liver regeneration after liver resection in rats
(Via Medica, 2016)The aim of the present study was to assess the influence of quercetine (QE) on liver regeneration after partial hepatectomy (PH) in rats. A total of 24 male Wistar albino rats were divided into three groups: sham-operated ... -
Effects of Urtica dioica on oxidative stress, proliferation and apoptosis after partial hepatectomy in rats
(Sage Publications Inc, 2015)The present study was performed to investigate the effect of Urtica dioica (UD) on liver regeneration after partial hepatectomy (PH) in rats. A total of 24 male Sprague Dawley rats were divided into three groups: sham-operated, ... -
The Evaluation of the Relationship between Bladder Cancer and Oxidative Stress Using NRF-2/KEAP-1 Pathway, Zinc and Copper Levels
(Urology and Nephrology Research Centre, 2021)Purpose: It has been shown that Copper and Zinc contribute to the structure of the antioxidant enzymes. In addition, NRF-2 and KEAP-1 complex have a powerful effect on the intracellular organization of the antioxidants. ... -
Investigation of hepatoprotective effect of some algae species on carbon tetrachloride-induced liver injury in rats
(Taylor and Francis Ltd., 2020)The aim of this study was to investigate hepatoprotective effect of some algae species such as Spirulina platensis, Chlorella vulgaris, Laminaria japonica, Sargassum sp. on experimental acute hepatotoxicity model that ... -
MAPK immunoreactivity in streptozotocin-induced diabetic rat testis
(Sociedade Brasileira para o Desenvolvimento de Pesquisa em Cirurgia, 2014)PURPOSE: To evaluate the alterations of two mitogen-activated protein kinases (MAPK)s, extracellular signal regulated kinase (ERK) and c-Jun NH2 terminal kinase (JNK), in the testes of male rats with experimental ... -
Melatonin attenuates oxidative stress, liver damage and hepatocyte apoptosis after bile-duct ligation in rats
(Sage Publications Inc, 2014)The goal of this study was to evaluate the possible protective effects of melatonin against cholestatic oxidative stress, liver damage and hepatocyte apoptosis in the common rats with bile duct ligation (BDL). A total of ... -
Melatonin reverses the oxidative stress and mitochondrial dysfunction caused by LETM1 silencing
(Wiley, 2020)LETM1 is a mitochondrial inner-membrane protein, which is encoded by a gene present in a locus of 4p, which, in turn, is deleted in the Wolf-Hirschhorn Syndrome, and is assumed to be related to its pathogenesis. The cellular ...