ORCID "0000-0003-2112-4056" Fakülteler için listeleme
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Are biological agents toxic to human chondrocytes and osteocytes?
İşyar, Mehmet; Bilir, Bülent; Yılmaz, İbrahim; Çakmak, Selami; Şirin, Duygu Yaşar; Yıldırım Güzelant, Aliye; Mahiroğulları, Mahir (Bmc, 2015)Purpose: The aim of the present study is to investigate the effects of biological agents (BAs) on human chondrocytes and osteocytes in vitro. Methods: Primary cell cultures obtained from gonarthrosis patients were divided ... -
Are the leading drugs against Staphylococcus aureus reallytoxic to cartilage?
Doğan, Mustafa; İşyar, Mehmet; Yılmaz, İbrahim; Bilir, Bülent; Şirin, Duygu Yaşar; Çakmak, Selami; Mahiroğulları, Mahir (Elsevier Science London, 2016)Many studies have shown that the toxic effects of local antibiotics on bone and cartilage limit orthopedic surgeons. In this study, we evaluated three antibacterial agents used locally to treat highly mortal and morbid ... -
Are treatment guides and rational drug use policies adequately exploited in combating respiratory system diseases?
Doğan, Mustafa; Mutiu, Levent C.; Yılmaz, İbrahim; Bilir, Bülent; Saraçoğlu Varol, Gamze; Yıldırım Güzelant, Aliye (Elsevier Science London, 2016)The aim of the present study was to increase awareness regarding the rational use of medicines. The data were obtained via the Material Resources Management System Module of the Ministry of Health. For the appropriateness ... -
Association of apelin, endoglin and endocan with diabetic peripheral neuropathy in type 2 diabetic patients
Bilir, Bülent; Bilir, Betül Ekiz; Yılmaz, I.; Atile, N. Soysal; Yıldırım, Tülay; Kara, Sonat Pınar; Aydın, M. (Verduci Publisher, 2016)OBJECTIVE: Diabetic peripheral neuropathy is a common complication of type-2 diabetes mellitus. Endocan, apelin and endoglin are thought to be associated with endothelial dysfunction, angiogenesis and inflammation. In this ... -
Asymmetric dimethylarginine contributes to airway nitric oxide deficiency in patients with COPD (Meeting Abstract)
Aydın, Murat; Altıntaş, Nejat; Mutlu, Levent Cem; Bilir, Bülent; Oran, Mustafa; Tukubas, Feti; Topçu, Birol (European Respiratory Soc Journals Ltd, 2015)[No Abstract Available] -
Effect of CPAP on New Endothelial Dysfunction Marker, Endocan, in People With Obstructive Sleep Apnea
Altıntaş, Nejat; Mutlu, Levent Cem; Akkoyun, Dursun Çayan; Aydın, Murat; Bilir, Bülent; Yılmaz, Ahsen; Malhotra, Atul (Sage Publications Inc, 2016)Obstructive sleep apnea (OSA) is associated with increased cardiovascular (CV) morbidity and mortality. Endocan is a surrogate endothelial dysfunction marker that may be associated with CV risk factors. In this study, we ... -
The effect of ezetimibe monotheraphy on mean platelet volume in patients with hyperlipidaemia: a retrospective study of 45 patients
Sertbaş, Yaşar; Sertbaş, Meltem; Ersoy, Uğur; Bilir, Bülent; Günaydın, Seracettin; Özdemir, Ali (Pakistan Medical Assoc, 2016)Objective: To investigate the effect of ezetimibe on platelet functions as a drug which increases mevalonate levels. Methods: This retrospective study was conducted in Istanbul, Turkey, and comprised record of normolipidaemic ... -
The effects of melatonin on liver functions in arsenic-induced liver damage
Bali, İlhan; Bilir, Bülent; Emir, Seyfi; Turan, Filiz; Yılmaz, Ahsen; Gökkuş, Tuba; Aydın, Murat (Turkish Surgical Assoc, 2016)Objective: Arsenic exposure is increasing in communities due to environmental pollution and industrial development. Arsenic is toxic to organ systems because it causes oxidative stress, enzymatic inhibition, and damage to ... -
Evaluation of neutrophil-to-lymphocyte ratio as a marker of inflammatory response in septic arthritis
Bilir, Bülent; İşyar, Mehmet; Yılmaz, İbrahim; Saraçoğlu Varol, Gamze; Çakmak, Selami; Doğan, Mustafa; Mahiroğulları, Mahir (Sage Publications Inc, 2015)Is neutrophil-to-lymphocyte ratio high in patients with septic arthritis? Septic arthritis may lead to higher rates of morbidity or even mortality if not diagnosed on time. This study was planned to answer the question ... -
Evaluation of SCUBE-1 and sCD40L biomarkers in patients with hypothyroidism due to Hashimoto's thyroiditis: a single-blind, controlled clinical study
Bilir, Bülent; Soysal Atile, Neslihan; Bilir, Betül Ekiz; Yılmaz, I.; Bali, İlhan; Altıntaş, Nejat; Güldiken, Sibel; Aydın, M. (Verduci Publisher, 2016)OBJECTIVE: This study was performed to investigate the levels of platelet activation marker SCUBE-1 and sCD40L which plays some role in the progression of atherosclerosis, in patients with hypothyroidism due to Hashimoto's ... -
The Predictive Role of Neutrophil to Lymphocyte ratio in Chronic Obstructive Pulmonary Disease
Bilir, Bülent; Altıntaş, Nejat; Aydın, Murat; Oran, Mustafa; Özsu, Savaş; Tutar, Umit (Modestum Ltd, 2016)Objective: Recently neutrophil-to-lymphocyte ratio (NLR) -the level of neutrophil reflecting the severity of inflammation and lymphocyte occurring after physiological stress has been gaining popularity, which was, along ... -
Protective Effect of Infliximab, a Tumor Necrosis Factor-Alfa Inhibitor, on Bleomycin-Induced Lung Fibrosis in Rats
Altıntaş, Nejat; Erboğa, Mustafa; Aktaş, Cevat; Bilir, Bülent; Aydın, Murat; Şengül, Aysun; Gürel, Ahmet; Topçu, Birol (Springer/Plenum Publishers, 2016)We aimed to investigate the preventive effect of Infliximab (IFX), a tumor necrosis factor (TNF)-alpha inhibitor, on bleomycin (BLC)-induced lung fibrosis in rats. Rats were assigned into four groups as follows: I-BLC ... -
Red cell distribution width and contrast-induced nephropathy in patients who underwent primary percutaneous coronary intervention reply
Akkoyun, Dursun Çayan; Akyüz, Aydın; Kurt, Ömer; Bilir, Bülent; Alpsoy, Şeref; Güler, Niyazi (Turkish Soc Cardiology, 2016)[No Abstract Available] -
Relationship between red cell distribution width and contrast-induced nephropathy in patients who underwent primary percutaneous coronary intervention
Akkoyun, Dursun Çayan; Akyüz, Aydın; Kurt, Ömer; Bilir, Bülent; Alpsoy, Şeref; Güler, Niyazi (Turkish Soc Cardiology, 2015)Objective: This study evaluated the relationship between contrast-induced nephropathy (CIN) and red cell distribution width (RDW) in patients who underwent primary percutaneous coronary intervention (PCI). Methods: A total ...