Yazar "Kumar, Naresh" için Fakülteler listeleme
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Some electrophilic reactivity studies of di-(2-indolyl)dibenzofurans and di-(2-indolyl)carbazoles
Şengül, İbrahim Fazıl; Somphol, Kittiya; Kandemir, Hakan; Kumar, Naresh; Black, David StC. (Pergamon-Elsevier Science Ltd, 2014)3,6-Bis-(2-indolyl)dibenzofurans 1,2, and carbazoles 3-6 underwent a range of electrophilic substitution reactions to produce formyl indoles 7-12, biindolyls 24-28 and 33-34, glyoxylamides 40-42, and amides 48. (C) 2014 ... -
Substituent effects in solid-state assembly of activated benzotriazoles
Wenholz, Daniel S.; Bhadbhade, Mohan; Kandemir, Hakan; Ho, Junming; Kumar, Naresh; Black, David StC. (Royal Soc Chemistry, 2019)Aromatic donor-acceptor stacking involving electron-rich -donors and electron-deficient -acceptors has been utilized in a broad spectrum of diverse applications to great effect. We report the discovery of unprecedented ... -
Synthesis and biological activity of novel mono-indole and mono-benzofuran inhibitors of bacterial transcription initiation complex formation
Mielczarek, Marcin; Thomas, Ruth V.; Ma, Cong; Kandemir, Hakan; Yang, Xiao; Bhadbhade, Mohan; Kumar, Naresh (Pergamon-Elsevier Science Ltd, 2015)Our ongoing research focused on targeting transcription initiation in bacteria has resulted in synthesis of several classes of mono-indole and mono-benzofuran inhibitors that targeted the essential protein-protein interaction ... -
Synthesis and biological evaluation of 2,5-di(7-indolyl)-1,3, 4-oxadiazoles, and 2-and 7-indolyl 2-(1,3,4-thiadiazolyl)ketones as antimicrobials
Kandemir, Hakan; Ma, Cong; Kutty, Samuel K.; Black, David StC.; Griffith, Renate; Lewis, Peter J.; Kumar, Naresh (Pergamon-Elsevier Science Ltd, 2014)A range of novel hydrazine bridged bis-indoles was prepared from readily available indole-7-glyoxyloylchlorides and 7-trichloroacetylindoles and underwent cyclodehydration to produce 2,5-di(7-indolyl)-1,3,4-oxadiazoles and ... -
Synthesis of a 7-(aminomethyl)indole and related bis-indole derivatives
Kandemir, Hakan; Şengül, İbrahim Fazıl; Kumar, Naresh; Black, David StC. (Arkat Usa Inc, 2016)A 7-(aminomethyl) indole is a useful precursor to form a new range of unsymmetrical and symmetrical 3-substituted amide-, imine-, and amine-linked 7,7'-bis-indoles. The reduction of an imine linked bis-indole leads to ... -
Synthesis of Imine and Amine-Linked Macrocycles Containing Tris-Indoles
Kandemir, Hakan; Şengül, İbrahim Fazıl; Kumar, Naresh; Black, David StC. (Csiro Publishing, 2017)The synthesis of 21-membered imine-and amine-linked tris-indole macrocycles starting from 7-nitroethylindoles is described. The 7-nitroethylindoles are converted to 2,2'-diindolylmethanes and the nitro groups reduced to ... -
Synthesis, Reactivity and Biological Properties of Methoxy-Activated Indoles
Şengül, İbrahim Fazıl; Bingül, Murat; Kandemir, Hakan; Kumar, Naresh; Black, David StC. (Societa Chimica Italiana, 2021)Indoles continue to play a central role in the development of new structures of chemical and biological interest. They are the source of numerous biologically active natural products by virtue of their derivation from ...