Yazar "Aktaş, Cevat" için Fakülteler listeleme
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Melatonin attenuates oxidative stress, liver damage and hepatocyte apoptosis after bile-duct ligation in rats
Aktaş, Cevat; Kanter, Mehmet; Erboğa, Mustafa; Mete, Rafet; Oran, Mustafa (Sage Publications Inc, 2014)The goal of this study was to evaluate the possible protective effects of melatonin against cholestatic oxidative stress, liver damage and hepatocyte apoptosis in the common rats with bile duct ligation (BDL). A total of ... -
Morphological investigation of alcohol-induced hepatocyte apoptosis and liver injury in rats
The aim of this study was to morphologicall investigation of alcohol-induced hepatocyte apoptosis and liver injury in rats. A total of 20 male Sprague-Dawley rats were divided into two groups: control, and alcohol treated; ... -
N-Nitro-L-Arginine Methyl Ester (L-NAME) Preeclampsia Model in Rats to Examine the Effect of Curcumin
Erdoğan, Hasan; Aktaş, Cevat; Şener, Ümit; Kumral, Bahadır; Erdoğan, Filiz; Soydan, Zekeriya; Erboğa, Mustafa (Wiley-Blackwell, 2015)[No Abstract Available] -
Neuroprotective effect of ebselen against intracerebroventricular streptozotocin-induced neuronal apoptosis and oxidative stress in rats
Ünsal, Cüneyt; Oran, Mustafa; Albayrak, Yakup; Aktaş, Cevat; Erboğa, Mustafa; Topçu, Birol; Özen, Oğuz Aslan; Ateş, Özkan (Sage Publications Inc, 2016)The goal of this study was to examine the neuroprotective effect of ebselen against intracerebroventricular streptozotocin (ICV-STZ)-induced oxidative stress and neuronal apoptosis in rat brain. A total of 30 adult male ... -
Neuroprotective effect of quercetin against oxidative damage and neuronal apoptosis caused by cadmium in hippocampus
Kanter, Mehmet; Ünsal, Cüneyt; Aktaş, Cevat; Erboğa, Mustafa (Sage Publications Inc, 2016)The purpose of the present investigation was to evaluate cadmium (Cd)-induced neurotoxicity in hippocampal tissues and beneficial effect of quercetin (QE) against neuronal damage. A total of 30 male rats were divided into ... -
Nigella sativa attenuates bleomycin-induced pulmonary fibrosis in rats by inhibition of inflammation, fibrosis, and inducible nitric oxide synthase
Erboğa, Mustafa; Erboğa, Zeynep Fidanol; Dönmez, Yeliz Bozdemir; Aktaş, Cevat; Kanter, Mehmet (Ondokuz Mayis Universitesi, 2015)The present study investigated the anti-oxidant, anti-inflammatory and anti-fibrotic potential of Nigella sativa (NS) against bleomycin (BLC)-induced lung injury and fibrosis, an experimental animal model. A total of 18 ... -
Protective Effect of Alpha Lipoic Acid on Rat Sciatic Nerve Ischemia Reperfusion Damage
Turamanlar, Ozan; Özen, Oğuz Aslan; Songur, Ahmet; Yağmurca, Murat; Akçer, Sezer; Mollaoğlu, Hakan; Aktaş, Cevat (Galenos Publ House, 2015)Background: Alpha lipoic acid is a potent antioxidant that plays numerous roles in human health. This study examined the effect of ALA on rat sciatic nerve ischemia reperfusion damage. Aims: Protective effect of alpha ... -
Protective Effect of Curcumin on Liver Damage Induced by Biliary Obstruction in Rats
Erenoglu, Cengiz; Kanter, Mehmet; Aksu, Burhan; Sağıroğlu, Tamer; Ayvaz, Süleyman; Aktaş, Cevat; Erboğa, Mustafa (Galenos Publ House, 2011)Objective: The aim of this study is to evaluate the possible protective effects of curcumin against cholestatic oxidative stress and liver damage in common bile duct ligated rats. Material and Methods: A total of 18 male ... -
Protective Effect of Infliximab, a Tumor Necrosis Factor-Alfa Inhibitor, on Bleomycin-Induced Lung Fibrosis in Rats
Altıntaş, Nejat; Erboğa, Mustafa; Aktaş, Cevat; Bilir, Bülent; Aydın, Murat; Şengül, Aysun; Gürel, Ahmet; Topçu, Birol (Springer/Plenum Publishers, 2016)We aimed to investigate the preventive effect of Infliximab (IFX), a tumor necrosis factor (TNF)-alpha inhibitor, on bleomycin (BLC)-induced lung fibrosis in rats. Rats were assigned into four groups as follows: I-BLC ... -
Protective Effect of Quercetin Against Renal Toxicity Induced by Cadmium in Rats
Aktoz, Tevfik; Kanter, Mehmet; Uz, Yesim Hulya; Aktaş, Cevat; Erboğa, Mustafa; Atakan, İrfan Hüseyin (Galenos Publ House, 2012)Objective: The aim of the present study was to examine the protective effect of quercetine (QE) against cadmium (Cd)-induced renal toxicity. Material and Methods: A total of 24 male Wistar albino rats were divided into ... -
Protective effects of fish omega-3 fatty acids on doxorubicin-induced testicular apoptosis and oxidative damage in rats
Uygur, Ramazan; Aktaş, Cevat; Tülübaş, Feti; Uygur, Emine; Kanter, Mehmet; Erboğa, Mustafa; Özen, Oğuz Aslan (Wiley-Blackwell, 2014)The aim of this study was to examine the protective effects of fish omega-3 (n-3) fatty acids on acute doxorubicin (DOX)-induced testicular apoptosis and oxidative damage. 24 male rats were divided into three groups: ... -
Protective effects of irbesartan and alpha lipoic acid in STZ-induced diabetic nephropathy in rats
Kanter, Mehmet; Sen, Saniye; Dönmez, Salim; Aktaş, Cevat; Üstündağ, Sedat; Erboğa, Mustafa (Taylor & Francis Ltd, 2010)The aim of this study was designed to investigate the possible beneficial effects of the angiotensin (ang) II T-1 (AT(1)) receptor blocker, irbesartan (Irb), and the alpha lipoic acid (ALA) in streptozotocin (STZ)-induced ... -
Protective effects of melatonin against arsenic-induced apoptosis and oxidative stress in rat testes
Uygur, Ramazan; Aktaş, Cevat; Çağlar, Veli; Uygur, Emine; Erdoğan, Hasan; Özen, Oğuz Aslan (Sage Publications Inc, 2016)This study aimed to investigate the protective effects of melatonin against arsenic-induced apoptosis and oxidative stress in rat testes. A total of 27 male rats were divided into 3 groups: control (saline: 5 ml kg(-1) ... -
Protective Effects of Onion Extract on Cadmium-Induced Oxidative Stress, Histological Damage, and Apoptosis in Rat Heart
Alpsoy, Şeref; Kanter, Mehmet; Aktaş, Cevat; Erboğa, Mustafa; Akyüz, Aydın; Akkoyun, Dursun Çayan; Oran, Mustafa (Humana Press Inc, 2014)To date, there is no available information on the protective effect of onion (Allium cepa) extract (AcE) on cadmium (Cd)-induced cardiotoxicity. The present study was performed to assess the possible antioxidant and ... -
Protective effects of quercetin against apoptosis and oxidative stress in streptozotocin-induced diabetic rat testis
Kanter, Mehmet; Aktaş, Cevat; Erboğa, Mustafa (Pergamon-Elsevier Science Ltd, 2012)The aim of this study was to investigate the protective effect of quercetin (QE) on oxidative stress, apoptosis, and cell proliferation in the rat testis after streptozotocin (STZ)-induced diabetes. Diabetes was induced ... -
Protective effects of quercetin on testicular torsion/detorsion-induced ischaemia-reperfusion injury in rats
Aktoz, Tevfik; Kanter, Mehmet; Aktaş, Cevat (Wiley-Blackwell, 2010)P>The aim of this study was to investigate the protective effect of quercetin (QE) on testicular torsion/detorsion-induced ischaemia-reperfusion (I/R) injury. A total of 24 male Wistar albino rats were divided into three ... -
Protective effects of thymoquinone against apoptosis and oxidative stress by arsenic in rat kidney
Şener, Ümit; Uygur, Ramazan; Aktaş, Cevat; Uygur, Emine; Erboğa, Mustafa; Balkaş, Gülseren; Erdoğan, Hasan (Taylor & Francis Ltd, 2016)We aimed to investigate the protective role of thymoquinone (TQ) by targeting its antiapoptotic and antioxidant properties against kidney damage induced by arsenic in rats. We have used the 24 male Sprague-Dawley rats. ... -
Protective effects of Urtica dioica L. on experimental testicular ischaemia reperfusion injury in rats
Aktaş, Cevat; Erbo?a, Mustafa; Fidanol Erboğa, Zeynep; Dönmez, Yeliz Bozdemir; Topçu, Birol; Gürel, Aydın (Wiley, 2017)In this study, it was aimed to examine the effects of Urtica dioica L. (UD) that has antioxidant feature in the experimental testicular I/R model in rats in terms of anti-apoptotic and antioxidative effects. In our study, ... -
Quercetin ameliorates methotrexate-induced renal damage, apoptosis and oxidative stress in rats
Erboğa, Mustafa; Aktaş, Cevat; Erboğa, Zeynep Fidanol; Dönmez, Yeliz Bozdemir; Gürel, Ahmet (Taylor & Francis Ltd, 2015)Background: In the present study, the protective and therapeutic effects of quercetin (QE) on renal injury induced by methotrexate (MTX) have been examined. Materials and methods: A total of 24 male rats were divided into ... -
Quercetin Inhibits Heart Injury in Lipopolysaccharide-induced Endotoxemic Model by Suppressing the Effects of Reactive Oxygen Species
Akkoyun, Dursun Çayan; Akyüz, Aydın; Doğan, Mustafa; Erboğa, Mustafa; Aktaş, Cevat; Çağlar, Veli; Gürel, Ahmet (Sci Printers & Publ Inc, 2016)OBJECTIVE: To examine the histopathological and biochemical effects of quercetin (QE), which has antioxidant properties, on damaged heart muscle in a lipopolysaccharide (LPS)-induced endotoxemia model in rats. STUDY DESIGN: ...