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Toplam kayıt 31, listelenen: 21-30
Next generation sequencing analysis of BRCA1 and BRCA2 identifies novel variations in breast cancer
(Elsevier Inc., 2020)
Mutations in two major breast cancer susceptibility genes, BRCA1 and BRCA2, have been identified to be the most important predisposing factors for the development of breast cancer. Thus, BRCA1/2 testing is a well-established ...
The place of infectious markers in predicting culture positivity in patients with renal failure hospitalized with suspected infection
(John Wiley and Sons Inc, 2022)
Infectious diseases are an important cause of mortality in patients with renal failure. The markers used to diagnose infection in patients with renal failure have various limitations. Culture positivity is an objective ...
Bioinformatic Analysis and in Vitro Validation of Let-7b and Let-7c in Breast Cancer
(Elsevier Ltd, 2020)
Members of the let-7 family of miRNAs are well-known with their tumor suppressor properties as they are expressed at low levels in several types of human malignancies. Among them, let-7b and let-7c have gained special ...
Relationship between serum soluble endothelial protein C receptor level and COVID-19 findings
(NLM (Medline), 2021)
Coronavirus-related disease-2019 (COVID-19)-associated coagulopathy presents predominantly with thrombosis and leads to complications in close association with inflammatory process. Soluble endothelial protein C receptor ...
Correction of more hallux valgus pathologic disorders with a single distal osteotomy a new surgical technique
(American Podiatric Medical Association, 2021)
Background: Hallux valgus, one of the most common deformities of the great toe, may cause pain, dysfunction, and impaired gait pattern. In this retrospective study we report the results of a new type of distal metatarsal ...
Factors Affecting Long-Term Survival Following Pulmonary Metastasectomy of Renal Cell Carcinoma
(Urology and Nephrology Research Centre, 2020)
Purpose: Role of pulmonary metastasectomy of renal cell carcinoma (RCC) is significant considering its contribution to survival rates. The aim of this study is to present the prognostic factors affecting the surgical ...
Effect of HER2 and Fascin expression on muscle-invasive bladder cancers: Classification by basaloid and luminal phenotypes
(NLM (Medline), 2022)
Purpose: The present study aims to identify basaloid and luminal molecular groups and the p53-like sub-group, which is a sub-group of the luminal group, using a specific immunohistochemical panel and investigate human ...
Efficacy of subsequent treatments in patients with hormone-positive advanced breast cancer who had disease progression under CDK 4/6 inhibitor therapy
(BioMed Central Ltd, 2023)
Background: There is no standard treatment recommended at category 1 level in international guidelines for subsequent therapy after cyclin-dependent kinase 4/6 inhibitor (CDK4/6) based therapy. We aimed to evaluate which ...
Histopathological and molecular findings in 98 cases of endometrial carcinoma: MMR, p53 and next generation sequencing
(Elsevier GmbH, 2023)
Gynecological malignancies arise from hereditary and somatic mutations, transcriptional aberrations, and genomic alterations influenced by epigenetic factors. This study aims to identify the mutations and their frequency ...
Effect of demographic features on morphometric variables of the knee joint: Sample of a 20 to 40-year-old Turkish population
(Lippincott Williams and Wilkins, 2023)
This study aimed to investigate the relationship between body mass index (BMI), age, and sex and morphological risk factors that may cause internal knee injuries. The magnetic resonance images of 728 participants who met ...