Yazar "Karaboğa, İhsan" için listeleme
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Caffeic acid phenethyl ester ameliorates pulmonary inflammation and apoptosis reducing Nf-κβ activation in blunt pulmonary contusion model
Karaboğa, İhsan (Turkish Assoc Trauma Emergency Surgery, 2019)BACKGROUND: Pulmonary contusion (PC) is an important life-threatening clinical condition characterized by lung injury and inflammation. Caffeic acid phenethyl ester (CAPE) is a biological agent with potent antioxidant and ... -
Cardioprotective effect of caffeic acid phenethyl ester on cardiac contusion following blunt chest trauma in rats
Bıçakçı, N.; Karaboğa, İhsan; Dökmeci, Ayşe Handan; Güzel, S.; Fidanol Erboğa, Z. (Taylor and Francis Ltd, 2019)We investigated the effects of caffeic acid phenethyl ester (CAPE) on cardiac damage after blunt chest injury. Forty male adult Wistar albino rats were divided into four groups; control, cardiac contusion, cardiac contusion ... -
Ebselen, an Active Seleno-Organic Compound, Alleviates Articular Cartilage Degeneration in a Rat Model of Knee Osteoarthritis
Okuyan, Hamza Malik; Yurtal, Ziya; Karaboğa, İhsan; Kaçmaz, Filiz; Kalacı, Aydıner (Springernature, 2022)Osteoarthritis (OA) is a prevalent articular disease mainly characterized by extracellular matrix degradation, apoptosis, and inflammation, which lead to cartilage destruction and abnormal bone metabolism. With undesirable ... -
Effect of hesperetin on inflammatory and oxidative status in trinitrobenzene sulfonic acid-induced experimental colitis model
Polat, Fatin Rüştü; Karaboğa, İhsan; Polat, Muhammed Semih; Erboğa, Zeynep Fidanol; Yılmaz, Ahsen; Güzel, Savaş (Cellular and Molecular Biology Association, 2018)In our study, the effect of hesperetin on inflammatory and oxidative status in trinitrobenzene sulfonic acid (TNBS)-induced experimental colitis model was investigated through different methods. Eighteen Wistar albino male ... -
Effect of hesperetin on systemic inflammation and hepatic injury after blunt chest trauma in rats
Duran, Y.; Karaboğa, İhsan (Taylor and Francis Ltd, 2020)We investigated the protective effect of hesperetin on hepatic damage after blunt chest trauma in rats using histological and biochemical methods. We used 18 adult male rats in three groups of six: control, chest trauma ... -
The effect of ozone (O3) therapy in addition to high dose methylprednisolone on hypoxia inducible factor-1 alpha (HIF-1?) expression in rabbit cornea
Introduction: To investigate the effect of ozone (O3) therapy on cornea subjected to systemically used high dose methylprednisolone (MP) ina rabbit model.Methods: Twenty-four New Zealand White adult male rabbits were ... -
Etanol Uyarımlı Sıçan Akut Mide Mukoza Hasar Modelinde Hypericum Perforatum'un Koruyucu Etkilerinin İncelenmesi
Karaboğa, İhsan; Dökmeci, Ayşe Handan; Ovalı, Mehmet Akif; Yılmaz, Ahsen (Namık Kemal Üniversitesi, 2017)Bu çalışma sıçanlarda absolü alkol ile oluşturulan gastrik ülserde H. perforatum'un antiapoptotik ve antiinflamatuvar etkilerini değerlendirmek amacıyla yapılmıştır. -
Gastroprotective effect of apricot kernel oil in ethanol-induced gastric mucosal injury in rats
Karaboğa, İhsan; Ovalı, M. A.; Yılmaz, A.; Alpaslan, Mehmet (Taylor & Francis Ltd, 2018)We investigated the gastroprotective effect of apricot kernel oil on ethanol induced gastric ulcer in rats. Male Wistar albino rats were divided into control, ethanol and apricot kernel oil + ethanol groups. The fatty acid ... -
The hepatoprotective effect of Aloe vera on ischemia-reperfusion injury in rats
Şehitoğlu, Müşerref Hilal; Karaboğa, İhsan; Kiraz, Aslı; Kiraz, Hasan Ali (Kare Publ, 2019)OBJECTIVE: Aloe vera is known for its antioxidant properties. In this experimental study, we aimed to investigate the efficacy of Aloe vera in ischemia-reperfusion (I/R) liver injury in rats. METHODS: Male Wistar Albino ... -
Humic Acid Has Protective Effect on Gastric Ulcer by Alleviating Inflammation in Rats
Şehitoğlu, Müşerref Hilal; Öztopuz, Ö.; Karaboğa, İhsan; Ovalı, M. A.; Uzun, Metin (Pleiades journals, 2022)The new agents are needed in treatment of gastric ulcer that have less side effects, adequate efficacy, and no drug interactions. In this study, we aimed to investigate the potential protective effects of humic acid on ... -
Immunohistochemical examination of anti-inflammatory and anti-apoptotic effects of hesperetin on trinitrobenzene sulfonic acid induced colitis in rats
Polat, Fatin Rüştü; Karaboğa, İhsan (Taylor & Francis Ltd, 2019)The trinitrobenzene sulfonic acid (TNBS) induced colitis model is used to investigate the pathogenesis of ulcerative colitis. Colon inflammation and apoptosis are associated with tissue damage in ulcerative colitis. ... -
In vivo protective effects of upper zone of growth plate and cartilage matrix associated protein against cartilage degeneration in a monosodium iodoacetate induced osteoarthritis model
Okuyan, H.M.; Terzi, M.Y.; Karaboğa, İhsan; Doğan, S.; Kalacı, A. (Canadian Science Publishing, 2020)Osteoarthritis (OA) is a degenerative disease affecting the majority of over 65 year old people and characterized by cartilage degeneration, subchondral abnormal changes, and inflammation. Despite the enormous socioeconomic ... -
Investigation of the protective effect of erdosteine against cyclosporine-induced injury in rat liver with histological and biochemical methods
Nacar, Ahmet; Karaboğa, İhsan; Okuyan, H.M.; Kaplan Sefil, Nebihat; Nacar, Emel; Motor, Sedat; Özkan, Orhan Veli (Tubitak Scientific & Technical Research Council Turkey, 2015)Background/aim: In the present study, the protective effect of erdosteine against cyclosporine-induced injury in rat liver was investigated with histological and biochemical methods. Materials and methods: Thirty-two Wistar ... -
Investigation of the relationship between the Th17/IL-23 pathway and innate-adaptive immune system in TNBS-induced colitis in rats
Karaboğa, İhsan; Demirtaş, Selim; Karaca, Turan (Mashhad Univ Med Sciences, 2017)Objective(s): This study was aimed at investigating immune activations of the 2,4,6-trinitrobenzene sulfonic acid(TNBS)-induced colitis model in colonic mucosa by immunohistochemical and Western blot methods. Materials and ... -
Kafeik Asit Fenetil Ester Sıçanlarda Göğüs Travması Sonrası Gelişen Hepatik Hasarı Nükleer Faktör Kappa Beta ve İndüklenebilir Nitrik Oksit Sentezini Baskılayarak Azaltır
Karaboğa, İhsan (2019)Amaç: Bu çalışmada göğüs travması modeli oluşturulansıçanlarda meydana gelen hepatik hasara karşı kafeik asitfenetil ester (KAFE)' nin Nükleer Faktör Kappa Beta (Nf-??)ve indüklenebilir nitrik oksit sentaz (iNOS) aktivitesi ... -
Natriüretik Peptitler
Demirtaş, Selim; Karaboğa, İhsan; Karaca, Turan (Namık Kemal Üniversitesi, Tıp Fakültesi, 2014)Natriüretik peptitler; atrial natriüretik peptit (ANP), B-tipi natriüretik peptit (BNP), C-tipi natriüretik peptit (CNP), Dtipi natriüretik peptit (DNP) nörohormonlarından oluşur. Bu hormonlar kalp, beyin, endotel ve ... -
Ozone treatment for high-dose systemic Steroid-Induced retinal injury
Yıldız, Aydın; Şehitoğlu, Müşerref Hilal; Karaboğa, İhsan; Arıkan, Sedat (Taylor & Francis Ltd, 2020)Objective To investigate the effect of high-dose systemic steroids on retinal tissues and the effectiveness of ozone (O-3) therapy. Methods Twenty-four New Zealand white rabbits were divided into three groups of eight. ... -
Protective effect of gel form of gastric gavage applicated aloe vera on ischemia reperfusion injury in renal and lung tissue
Şahin, Hasan; Yener, Ali Ümit; Karaboğa, İhsan; Şehitoğlu, Müşerref Hilal; Doğu, Tuğba; Altınışık, Hatice Betül; Şimşek, Tuncer (C M B Assoc, 2017)The aloe vera plant has become increasingly popular in recent years. This study aimed to research the effect of aloe vera to prevent renal and lung tissue damage in an experimental ischemia-reperfusion (I/R) injury model. ... -
Protective Effects of Hesperetin Against Lipopolysaccharide-induced Acute Renal Injury in Rat
Kaya, Serkan; Karaboğa, İhsan (Galenos Publ House, 2022)Objective: In this study, it was aimed to investigate the effects of hesperetin on renal transforming growth factor-beta 1 (TGF-beta 1) expression and apoptosis in rat lipopolysaccharide (LPS)-induced acute renal injury ... -
Protective effects of hesperetin on lipopolysaccharide-induced acute lung injury in a rat model
Kaya, S.; Kaya, S.A.; Polat, E.; Erboğa, Zeynep Fidanol; Duran, Y.; Polat, Fatin Rüştü; Karaboğa, İhsan (Baycinar Medical Publishing, 2020)Background: In this experimental study, we aimed to investigate the effects of hesperetin, a natural flavonoid, on a lipopolysaccharideinduced acute lung injury model in rats. Methods: Between March 2019 and May 2019, a ...