Konu "Fibrosis" için listeleme
Toplam kayıt 9, listelenen: 1-9
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Effect of Urtica Dioica against Doxorubicin-Induced Cardiotoxicity in Rats through Suppression of Histological Damage, Oxidative Stress and Lipid Peroxidation
(Modestum Ltd, 2016)Objective: Doxorubicin (DOX) is a highly effective anti-cancer drug with limited clinical use due to its serious cardiotoxicity. Urtica dioica L. seeds (UD), have been widely used in folk medicine, particularly in the ... -
Effects of jnk inhibitor on inflammation and fibrosis in the ovary tissue of a rat model of polycystic ovary syndrome
(E-Century Publishing Corp, 2015)Objective: In our study, we aimed to investigate the effects of Jun N-terminal kinase inhibitor (SP600125) on fibrosis and inflammation in rats with polycystic ovary syndrome (PCOS). Method: 50 Wistar-albino rats were ... -
Effects of mitomycin C and cyclosporine A on experimentally induced glaucoma filtration surgery in rabbit model
(Ecole Nationale Veterinaire Toulouse, 2016)The present study aims at investigating the effect of topical administration of mitomycin C (MMC) used solely and combined with cyclosporine A (MMC+CsA) on inhibition of the granulation tissue proliferation in experimentally ... -
The Effects of Quercetin on Acute Lung Injury and Biomarkers of Inflammation and Oxidative Stress in the Rat Model of Sepsis
(Springer/Plenum Publishers, 2016)Experimental studies indicate that sepsis causes remote organ injury although the molecular mechanism has not been clearly defined. In this report, the role of oxidative damage, and inflammation on lung injury, following ... -
Hyperbaric oxygen treatment ameliorates lung injury in paraquat intoxicated rats
(E-Century Publishing Corp, 2015)Paraquat (PQ) is an agrochemical agent commonly used worldwide, which can cause acute lung injury (ALI) and death. Hyperbaric oxygen treatment (HBOT) is a therapeutic method, but the mechanisms of the protective effect of ... -
Melatonin attenuates oxidative stress, liver damage and hepatocyte apoptosis after bile-duct ligation in rats
(Sage Publications Inc, 2014)The goal of this study was to evaluate the possible protective effects of melatonin against cholestatic oxidative stress, liver damage and hepatocyte apoptosis in the common rats with bile duct ligation (BDL). A total of ... -
Rapamycin Improves Vascular Remodelling in a Controlled Rat Model of Monocrotaline-Induced Pulmonary Hypertension
(Univ West Indies Faculty Medical Sciences, 2023)Background: Pulmonary arterial hypertension (PAH) is a serious disease characterized by the progressive elevation of the pulmonary arterial resistance, leading to the right ventricular failure and death. Objective: To ... -
The role of NMDA glutamate receptors in lung injury caused by chronic long-term intermittent hypobaric hypoxia
(Assoc Bras Divulg Cientifica, 2023)Chronic intermittent hypoxia (CIH), a component of sleep apnea-hypopnea syndrome, is suggested to cause damage to lung tissue, and the role of glutamate is not well studied. We used a chronic long-term intermittent hypobaric ... -
Urotensin-II Prevents Cartilage Degeneration in a Monosodium Iodoacetate-Induced Rat Model of Osteoarthritis
(Springer, 2022)Osteoarthritis (OA) is a common degenerative articular disorder caused by traumatic or spontaneous factors such as genetics, obesity, and advanced age. Comprehending the pathogenic mechanism of OA ensures the development ...