Yazar "Bozgeyik, Esra" için listeleme
-
Application of ultrasound to the organic cornelian cherry (Cornus mas L.) vinegar: Changes in antibacterial, antidiabetic, antihypertensive, and anticancer activities
Erdal, Berna; Akalın, Ramadan Bilgin; Yılmaz, Bahar; Bozgeyik, Esra; Yıkmış, Seydi (Wiley, 2022)In this study, to determine their alternative/complementary properties, organic cornelian cherry vinegar samples prepared by traditional (CCV), thermal pasteurization (P-CCV), and ultrasound (UT-CCV) methods were tested ... -
ARID3A-mediated modulation of TP73 and TP73-AS1 in osteosarcoma cells
Saadat, Khandakar A.S.M.; Bozgeyik, Esra; Arman, Kaifee; Bozgeyik, İbrahim; İkeda, M.A. (Elsevier Inc, 2020)Osteosarcoma is the most common primary malignancy arising from bone. Increasing mass of indications suggest that long non-coding RNAs (lncRNAs) play crucial roles in the development of progressions of human cancers including ... -
Bioinformatic Analysis and in Vitro Validation of Let-7b and Let-7c in Breast Cancer
Bozgeyik, Esra (Elsevier Ltd, 2020)Members of the let-7 family of miRNAs are well-known with their tumor suppressor properties as they are expressed at low levels in several types of human malignancies. Among them, let-7b and let-7c have gained special ... -
Cross-regulation of non-coding RNAs and their correlations with target protein-coding genes in CRC pathobiology
Bozgeyik, Esra; Bozgeyik, İbrahim (Elsevier B.V., 2019)Illuminating the correlations between non-coding RNAs and protein-coding genes are of great interest to understand more about the molecular mechanisms that drive malignant transformation and understanding such correlations ... -
THE EFFECT OF QUERCETIN AND QUERCETIN-3-D-XYLOSIDE ON BREAST CANCER PROLIFERATION AND MIGRATION
Yüksel, Tuğba Nurcan; Bozgeyik, Esra; Yayla, Muhammed (Dokuz Eylul Univ Inst Health Sciences, 2022)Background and Purpose: The aim of this study is to investigate the migration, wound healing, colony formation, and cytotoxic effects of Quercetin-3-D-xyloside (reynoutrin), a quercetin derivative, in breast cancer cells ... -
Effects of Non-Thermal Treatment on Gilaburu Vinegar (Viburnum opulus L.): Polyphenols, Amino Acid, Antimicrobial, and Anticancer Properties
Erdal, Berna; Yıkmış, Seydi; Demirok, Nazan Tokatlı; Bozgeyik, Esra; Levent, Okan (MDPI, 2022)Simple Summary In this study, traditionally produced vinegar made from gilaburu (C-GV) and thermally pasteurized gilaburu vinegar (P-GV), and (ultrasound-treated gilaburu vinegar (UT-GV) were evaluated. At the same time, ... -
Enhanced E2F1 activity increases invasive and proliferative activity of breast cancer cells through non-coding RNA CDKN2B-AS1
Bozgeyik, Esra; Saadat, Khandakar A.S.M.; Arman, K.; Bozgeyik, İbrahim; İkeda, M.A. (Elsevier B.V., 2020)Long non-coding RNAs have recently appeared as fundamental regulators of gene transcription in several biological processes, but only a few have known functional influences in the malignant transformation of breast cancer. ... -
Evaluation of purple onion waste from the perspective of sustainability in gastronomy: Ultrasound-treated vinegar
Yıkmış, Seydi; Erdal, Berna; Bozgeyik, Esra; Levent, Okan; Yinanç, Abdullah (Elsevier, 2022)Sustainable gastronomy is an important concept that improves the health and nutritional quality of society by supporting the preparation, production, and consumption of foods with environmental awareness. Purple onion ... -
Kanserin Ayırt Edici Özelliklerinde Kodlanmayan RNA'ların Rolü: Güncel Bir Bakış
Bozgeyik, Esra (2020)Kanser, genomda meydana gelen bir seri bozukluklar sonucu ortaya çıkan ciddi bir genetik hastalıktır. Yüksek verimli yeni nesil dizileme teknolojilerinin geliştirilmesi ve büyük ölçekli projelerin verilerinin yayınlanması ... -
Küçük Hücreli Olmayan Akciğer Kanseri Hücrelerinde Let-7b-5p'nin Apoptotik Genler İle İlişkisinin Araştırılması
Bozgeyik, Esra (2019)Amaç: Akciğer kanseri dünya genelinde kansere bağlı gerçekleşen ölümlerde kadınlarda ve erkeklerde ilk sıralarda yer almaktadır. Erken tanı yöntemlerinde ki gelişmeler ve yeni hedeflenen ajanların sayısının artmasına rağmen ... -
Long noncoding RNA ERICD interacts with ARID3A via E2F1 and regulates migration and proliferation of osteosarcoma cells
Arman, K.; Saadat, Khandakar A.S.M.; Iğcı, Y.Z.; Bozgeyik, Esra; İkeda, M.A.; Çakmak, Ecir Ali; Arslan, A. (Blackwell Publishing Ltd, 2020)Long noncoding RNA (lncRNA) dysregulation is known to be taking part in majority of cancers, including osteosarcoma. In one of our previous studies, we showed that lncRNA MEG3 is being regulated by microRNA-664a (miR-664a) ... -
MicroRNA-17-5p targets expression of cancer-associated genes in breast cancer cells
Bozgeyik, Esra (Elsevier B.V., 2020)Although there are several studies, biological function and therapeutic potential of miR-17-5p in breast cancer carcinogenesis remains muchly elusive. Specifically, its interaction with several cancer-associated genes ... -
miR-320a promotes p53-dependent apoptosis of prostate cancer cells by negatively regulating TP73-AS1 in vitro
Bozgeyik, Esra; Arslan, Ahmet; Temiz, Ebru; Batar, Bahadır; Koyuncu, İsmail; Tozkır, Hilmi (Academic Press Inc Elsevier Science, 2022)TP73 antisense RNA 1 (TP73-AS1) is an oncogenic long non-coding RNA that is activated in several types of cancers. It has been shown that the activity of TP73-AS1 is controlled by several miRNAs, but post -transcriptional ... -
MIRNA-mediated regulation of the PI3K/AKT signaling pathway in colorectal cancer: A study based on data mining
Bozgeyik, Esra; Bozgeyik, İbrahim (2019)Aim: In colorectal cancer (CRC), expression of genes involved in the PI3K/Akt signaling pathway varies significantly. Studies haveshown that microRNAs (miRNA) have important roles in the development of CRC. Accordingly, ... -
Next generation sequencing analysis of BRCA1 and BRCA2 identifies novel variations in breast cancer
Yıldız Tacar, Seher; Bozgeyik, Esra; Şeber, Erdoğan Selçuk; Yetişyiğit, Tarkan; Tozkır, Hilmi; Avcı, Okan; Arslan, Ahmet (Elsevier Inc., 2020)Mutations in two major breast cancer susceptibility genes, BRCA1 and BRCA2, have been identified to be the most important predisposing factors for the development of breast cancer. Thus, BRCA1/2 testing is a well-established ... -
Next-generation screening of a panel of genes associated with periodic fever syndromes in patients with Familial Mediterranean Fever and their clinical characteristics
Bozgeyik, Esra; Mercan, Rıdvan; Arslan, A.; Tozkır, Hilmi (Academic Press Inc., 2020)Familial Mediterranean Fever (FMF) is a hereditary fever syndrome that primarily affects Mediterranean populations. For the study, total number of 182 patients with FMF disease were enrolled and screening of a panel of ... -
Novel thiosemicarbazone derivative 17B interferes with the cell cycle progression and induce apoptosis through modulating downstream signaling pathways
Bozgeyik, Esra; Taşdemir Kahraman, Demet; Arman, Kaifee; Bozgeyik, İbrahim; Karaküçük İyidoğan, Ayşegül; Çakmak, Ecir Ali (Elsevier, 2020)Thiosemicarbazones (TSCs) are interesting group of chemical compounds that received significant levels of attention due their wide range of pharmacological effects including antibacterial, antiviral, and especially anti-tumor ... -
Novel zinc oxide nanoparticles of Teucrium polium suppress the malignant progression of gastric cancer cells through modulating apoptotic signaling pathways and epithelial to mesenchymal transition
Bozgeyik, İbrahim; Ege, Miray; Temiz, Ebru; Erdal, Berna; Koyuncu, İsmail; Temiz, Cengiz; Bozgeyik, Esra (Elsevier, 2023)Management of gastric cancer is still challenging due to resistance to current chemotherapeutics and recurrent disease. Moreover, green-synthesized zinc oxide nanoparticles (ZnO-NPs) using natural resources are one of the ... -
Organic cherry laurel (Prunus laurocerasus) vinegar enriched with bioactive compounds with ultrasound technology using artificial neural network (ANN) and response surface methodology (RSM): Antidiabetic, antihypertensive, cytotoxic activities, volatile profile and optical microstructure
Yıkmış, Seydi; Bozgeyik, Esra; Levent, Okan; Aksu, Harun (John Wiley and Sons Inc, 2021)This research aimed to enrich the bioactive components of organic cherry laurel vinegar with ultrasound and to examine the correlation between artificial neural network (ANN) and response surface methodology (RSM), and ... -
Prostat Kanseri Moleküler Mekanizmasında Kodlanmayan Rna'ların Rolü
Bozgeyik, Esra (2019)Kodlanmayan RNA’lar (ncRNA), bir açık okuma çerçevesibulunmayan ve proteine çevrilemeyen işlevsel RNAtranskriptleridir. NcRNA’lar transkripsiyon ve transkripsiyonsonrası işlemlerde düzenleyici rollere ve halenaçıklanmaya ...