Yazar "Bilgen, Türker" için listeleme
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Alloreactive memory B cell detection by flow cytometric cross match using polyclonally activated memory B cell culture supernatants
Akalan, Hande; Şirin, Duygu Yaşar; Yılmaz, İpek; Ata, Pınar; Kara, Veli Melih; Taşdemir, Nicel; Bilgen, Türker; Titiz, Mesut İzzet (Elsevier, 2022)In addition to alloantibodies, alloreactive memory B cell (mBC) evaluation has a potential for immunological risk assessment during transplantation processes. For the alloreactive mBCs evaluation currently, direct Flow ... -
Biyoaktif besin bileşeni piperlongumin'in histon deasetilaz enzim inhibitörü etkisinin araştırılması
Bora, Sümeyye (Tekirdağ Namık Kemal Üniversitesi, 2021)Beslenme ve Diyetetik alanında önemli bir yeri olan besin-gen etkileşimlerinin araştırılmasıyla besinlerin organizma üzerindeki etkilerinin daha iyi anlaşılması hedeflenmektedir. Son dönemde yapılan çalışmalarla çeşitli ... -
Comparison of Cytotoxic Flow Cytometric Cross Match With Complement Dependent Lymphocytotoxicity and Flow Cytometric Cross Match in Renal Transplant Patients
Bilgen, Türker; Canbakan, Mustafa; Şahin, G.; Titiz, Mesut İzzet (Elsevier USA, 2019)Cytotoxic flow cytometric crossmatch (cFCXM), identified by detecting complement-mediated cytotoxic cell death in addition to the capability of showing the alloantibodies binding onto lymphocytes at the same time, can ... -
Copy number increase of oncoprotein CIP2A is associated with poor patient survival in human head and neck squamous cell carcinoma
Routila, Johannes; Bilgen, Türker; Saramaki, Outi; Grenman, Reidar; Visakorpi, Tapio; Westermarck, Jukka; Ventela, Sami (Wiley, 2016)BackgroundCIP2A, an inhibitor of PP2A tumour suppressor function, is a widely overexpressed biomarker of aggressive disease and poor therapy response in multiple human cancer types. MethodsCIP2A and DPPA4 copy number ... -
Cytotoxic Antibody Detection by Means of Flow-Cytometric Cross-Match
Bilgen, Türker; Ata, P.; Tozkir, J.; Tozkır, Hilmi; Titiz, Mesut İzzet (Elsevier Science Inc, 2017)Background. Complement-dependent lymphocytotoxicity (CDC-XM) and flowcytometric (FCXM) cross-match are analyzed individually for each donor and recipient pair, because these techniques have fundamental differences for the ... -
Effects of idiopathic erythrocytosis on the left ventricular diastolic functions and the spectrum of genetic mutations: A case control study
Yeşilaltay, Alpay; Değirmenci, Hasan; Bilgen, Türker; Şirin, Duygu Yaşar; Bayır, Duygu; Değirmenci, Pelin; Turgut, Burhan (Lippincott Williams & Wilkins, 2022)Background: We have aimed at exposing left ventricular diastolic functions and the presence of known genetic mutations for familial erythrocytosis, in patients who exhibit idiopathic erythrocytosis. Methods: Sixty-four ... -
First observation of hemoglobin G-waimanalo and hemoglobin fontainebleau cases in the Turkish population
Canatan, D.; Bilgen, Türker; Çiftçi, V.; Yazıcı, G.; Delibaş, S.; Keser, İ. (Turkish Society of Hematology, 2016)[No abstract available] -
First Observation of Hemoglobin Kansas [beta 102(G4)Asn -> Thr, AAC > ACC] in the Turkish Population
Keser, İbrahim; Öztaş, Alev; Bilgen, Türker; Canatan, Duran (Galenos Yayincilik, 2015)[No Abstract Available] -
Flow Sitometri Cross Match Yöntemiyle Sitotoksik Etkinin Değerlendirilmesi
Titiz, Mesut İzzet; Bilgen, Türker (Namık Kemal Üniversitesi, 2016)Organ nakli günümüzde kronik organ yetmezliği olan hastalar için önemli bir tedavi seçeneğidir. Organ naklinde cross match testi, alıcıda vericinin HLA’ larına karşı mevcut olan antikorların gösterilmesi açısından ... -
FMR1 Gene Mutation Analysis and CGG Repeat Number Distribution from a Single Center
Arıkan, Yunus; Bilgen, Türker; Mıhcı, Ercan; Duman, Özgür; Karaman, Tuğba; Keser, İbrahim (Gazi Univ, Fac Med, 2022)Background: Mutation occurring in fragile X mental retardation 1 (FMR1) gene is acknowledged as the most common cause for X chromosome linked intellectual disability/mental retardation (XLID/XLMR). This gene harbors unstable ... -
Gap-PCR Screening for Common Large Deletional Mutations of beta-Globin Gene Cluster Revealed a Higher Prevalence of the Turkish Inversion/Deletion (delta beta)(0) Mutation in Antalya
Bilgen, Türker; Clark, Özden Altıok; Öztürk, Zeynep; Yesilipek, M. Akif; Keser, İbrahim (Galenos Yayincilik, 2016)Objective: Although the calculated carrier frequency for point mutations of the beta-globin gene is around 10% for Antalya Province, nothing is known about the profile of large deletional mutations involving the beta-globin ... -
GTG Banded Karyotype of Anatolian River Buffalo (Bubalus bubalis, 2n=50)
Soysal, Mehmet İhsan; Bilgen, Türker; Perucattı, Angela; Lannuzzı, Leopoldo (Namık Kemal Üniversitesi, Ziraat Fakültesi, 2016)The water buffalo (Bubalus bubalis) is one of the most important farm animals of Turkey. There are two types of the water buffalo: river and swamp. While the chromosome number of the river type is 2n=50, that of swamp type ... -
Induction of fetal hemoglobin by modulation of epigenetic and genetic factors in beta thalassemia major patients
Keser, İbrahim; Arikan, Y.; Kupesiz, A.; Bilgen, Türker; Kurtoglu, E. (Nature Publishing Group, 2018)[No Abstract Available] -
Investigation of alpha globin gene mutations by complementary methods in Antalya
Keser, İbrahim; Mercan, T.K.; Bilgen, Türker; Kupesiz, O.A.; Arikan, Y.; Canatan, D. (Yuzuncu Yil Universitesi Tip Fakultesi, 2021)Alpha (?) thalassemia is one of the hemoglobinopaties that is inherited by autosomal recessive mode. It is caused by mutations on alpha-1 and alpha-2 globin genes. Deletional type mutations of globin genes have commonly ... -
A Novel Mutation in the Promoter Region of the -Globin Gene: HBB: c.-127G > C
Bilgen, Türker; Canatan, Duran; Delibas, Serpil; Keser, İbrahim (Taylor & Francis Ltd, 2016)Novel -globin gene mutations are still occasionally being reported, especially when evaluating milder phenotypes. We report here a novel putative mutation in the promoter region of the -globin gene and assess its clinical ... -
Öz şefkatin yeme tutumu, besin seçimi ve beden kitle indeksi ile ilişkisinin araştırılması
Ayar, Şehnaz (Tekirdağ Namık Kemal Üniversitesi, 2020)Öz şefkat ve beden kitle indeksi ilişkisini (BKİ), yeme tutumu ve besin seçimi gibi beden ağırlığını etkileyen faktörler doğrultusunda inceleyen sınırlı sayıda çalışma bulunmaktadır. Mevcut kesitsel çalışmada, yetişkin ... -
Piperlongumine increases the apoptotic effect of doxorubicin and paclitaxel in a cervical cancer cell line
Şeber, Erdoğan Selçuk; Şirin, Duygu Yaşar; Yetişyiğit, Tarkan; Bilgen, Türker (Wolters Kluwer Medknow Publications, 2020)Objective: Piperlongumine (PL) is an alkaloid derived from the edible pepper (Piper longum L) and it has been described to have various biologic activities including anticancer effects. Our aim in this study was to assess ... -
Protective effects of Acetobacter ghanensis against gliadin toxicity in intestinal epithelial cells with immunoregulatory and gluten-digestive properties
Doğuer, Çaglar; Akalan, Hande; Demirok, Nazan Tokatlı; Erdal, Berna; Mete, Rafet; Bilgen, Türker (Springer Heidelberg, 2022)Purpose The aim of this study was to establish whether Acetobacter ghanensis, the probiotic characteristics of which were evaluated previously, attenuates gliadin-induced toxicity in intestinal epithelial cells with ... -
Türk propolisinin histon deasetilaz (HDAC) enzim aktivitesine etkisinin araştırılması
Başar, Meleknur (Tekirdağ Namık Kemal Üniversitesi, 2021)Bireylerin beslenme ve yaşam tarzı çeşitli epigenetik değişikliklere neden olarak vücudun fizyolojik ve patolojik süreçlerini etkileyebilmektedir. Son yıllarda yapılan çalışmalarda çeşitli besin ve besin bileşenlerinin ... -
Türk propolisinin hücre döngüsü üzerine etkisinin araştırılması
Terzi, Büşra (Tekirdağ Namık Kemal Üniversitesi, 2021)Propolis bal arılarının bitkilerden topladıkları çeşitli ürünleri kullanarak ürettikleri reçinemsi doğal bir maddedir. Propolis eski çağlardan beri başta sağlık olmak üzere diğer alanlarda da yaygın bir şekilde kullanılmaktadır. ...