Yazar "Akpınar, Seval" için listeleme
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Cardiac amyloidosis in a young female under follow-up with mitral regurgitation
Barutcu, A.; Özdemir, Sevilay; Akpınar, Seval (Oxford Univ Press, 2019)[No Abstract Available] -
Defibrotide combined with triple therapy including posttransplant cyclophosphamide, low dose rabbit anti-t-lymphocyte globulin and cyclosporine is effective in prevention of graft versus host disease after allogeneic peripheral blood stem cell transplantation for hematologic malignancies
Akpınar, Seval; Kayıkçı, Ömür; Tekgündüz, Emre (Pergamon-Elsevier Science Ltd, 2022)Endothelial dysfunction and damage play important roles in the pathophysiology of graft versus host disease (GvHD) and hepatic venoocclusive disease/sinusoidal obstruction syndrome (VOD/SOS). Preliminary evidence suggests ... -
Effectiveness of defibrotide in the prevention of hepatic venooclusive disease among adult patients receiving allogeneic hematopoietic cell transplantation: A retrospective single center experience
Kayıkçı, Ömür; Akpınar, Seval; Tekgündüz, Emre (Pergamon-Elsevier Science Ltd, 2022)Hepatic veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS) is one of the most life-threatening early complications following hematopoietic cell transplantation (HCT). Due to the high mortality rate of severe ... -
Efficacy and Safety of Ibrutinib Therapy in Patients with Chronic Lymphocytic Leukemia: Retrospective Analysis of Real-Life Data
Tombak, Anıl; Pepedil Tanrıkulu, Funda; Durusoy, Salih Sertaç; Dinçyürek, Hüseyin Derya; Kaya, Emin; Ümit, Elif Gülsüm; Ferhanoğlu, Burhan; Akpınar, Seval; Turgut, Burhan (Galenos Yayincilik, 2021)Objective: This study aimed to retrospectively evaluate the efficacy, safety, and survival outcome of single-agent ibrutinib therapy in chronic lymphocytic leukemia patients. Materials and Methods: A total of 136 patients ... -
Efficacy and Safety of Ibrutinib Use in Patients with Chronic Lymphocytic Leukemia in Real World Experiences: Results of a Prospective Multicenter Study
Tombak, Anıl; Pepedil Tanrıkulu, Funda; Durusoy, Salih Sertaç; Gürkan, Emel; Kaya, Emin; Ümit, Elif Gülsüm; Ferhanoğlu, Burhan; Akpınar, Seval (Amer Soc Hematology, 2019)[No Abstract Available] -
Hypofibrinolysis Is Associated with the Severity of COVID-19 Infection: the Role of Obesity
Oran, Mustafa; Akpınar, Seval; Doğan, Mustafa; Avcı, Burcu Altındağ; Çelikkol, Aliye; Turgut, Burhan (Carbone Editore, 2021)Introduction: Obesity, by causing hypofibrinolysis and thrombotic complications, ought to be a risk factor in terms of disease severity and mortality in COVID-19 infection. We aim to investigate the effects of obesity on ... -
İmmün trombositopenik purpuralı hastalarda B lenfosit alt gruplarının araştırılması
Demirel, Ahmet Tuğser (Tekirdağ Namık Kemal Üniversitesi, 2023)İmmün trombositopenik purpura trombosit sayısında düşüş ile seyreden otoimmunitenin rol oynadığı bir hastalıktır. Birinci basamak tedavi sonrasında remisyon oranı yüksek olmasına rağmen remisyon kaybı sık görülür ve nüks ... -
Koronavirüs Hastalığı (COVID-19) İle İlişkili Koagülopati
Akpınar, Seval (2020)2019 yılı sonunda Çin’in Wuhan eyaletinde “ağır akut solunum sendromu koronavirus-2 (SARS-CoV-2” olarak adlandırılan, zoonotik kaynaklı yeni bir koronavirus ortaya çıkmıştır. Koronavirüs hastalığı-2019 (COVID-19) olarak ... -
Kronik Lenfositik Lösemide Ölçülebilir Kalıntı Hastalık: Kuru Tüp Akım Sitometri Metoduyla Gerçek Yaşam Deneyimi
Akpınar, Seval; Turgut, Burhan (2022)Amaç: Kemoimmünoterapi (Kİ) sonrası ölçülebilir kalıntı hastalığın (ÖKH) negatifleşmesi uzun dönem progresyonsuz sağkalım (PS) ve genel sağkalım ile ilişkilidir. Ancak klinik çalışmalar dışında tedavi edilen hastalarda ... -
Procollagen C-proteinase enhancer-1 and renal failure in multiple myeloma
Bayrakçı, Nergiz; Özkan, Gülsüm; Akpınar, Seval; Ediz, Bartu; Yılmaz, Ahsen; Çelikkol, Aliye (Springer, 2022)Background Renal involvement is present in approximately 50% of multiple myeloma (MM) cases and is associated with a poor prognosis. Procollagen C-Proteinase Enhancer 1 (PCPE-1) is an extracellular matrix glycoprotein that ... -
Prospective registry of adult patients receiving therapeutic plasma exchange with a presumptive diagnosis of thrombotic microangiopathy (TMA): The Turkish hematology research and education group (ThREG)-TMA02 study
Akpınar, Seval; Tekgündüz, Emre; Esen, Ramazan; Yılmaz, Mehmet; Karakuş, Volkan; Vural, Filiz; Demirkan, Fatih (Pergamon-Elsevier Science Ltd, 2022)To understand who uses social media and how often they do so, we examined the personality traits that predict frequency of using a set of 10 different types of social media (e.g., social networks, blogs, virtual worlds). ... -
Real-Life Experience Regarding Clinical Characteristics and Treatment Outcome in Non-Cutaneous Peripheral T-Cell Lymphomas: A Multicenter Study of the Turkish Hematology Research and Education Group (ThREG)
Kayıkçı, Ömür; Mehtap, Ö.; Sarı, İ.; Demirkan, F.; Beyan, C.; Çetin, G.; Tekgündüz, E.; Akpınar, Seval (Turkish Society of Hematology, 2022)Objective: Peripheral T-cell lymphomas (PTCLs) are an uncommon and quite heterogeneous group of disorders, representing only 10%-15% of all non-Hodgkin lymphomas. Although both molecular and clinical studies have increased ... -
The Real-World Experience With Single Agent Ibrutinib in Relapsed/Refractory CLL
Akpınar, Seval; Doğu, Mehmet Hilmi; Çelik, Serhat; Ekinci, Ömer; Yönal Hindilerden, İpek; Dal, Mehmet Sinan; Altuntaş, Fevzi; Turgut, Burhan (Elsevier Inc., 2022)Introduction/Background: The emergence of novel agents targeting the B-cell receptor pathway and BCL-2 has significantly changed the therapeutic landscape of CLL. We evaluated the safety and efficacy of single-agent ibrutinib ... -
The role of oxidized phospholipids in COVID-19-associated hypercoagulopathy
Akpınar, Seval; Oran, Mustafa; Doğan, Mustafa; Çelikkol, Aliye; Erdem, İlknur; Turgut, Burhan (Verduci Editore s.r.l, 2021)OBJECTIVE: There is more pronounced hypercoagulation in COVID-19 infection than in other viral lung infections. Oxidized phospholipids (OxPLs) appear in COVID-19-infected lungs due to oxidative stress, after which they ... -
Severe Immune Thrombocytopenia in Pregnancy Treated with Eltrombopag. A Case Report.
Immune Thrombocytopenia (ITP) which is a common, acquired and autoimmune disease is defined as low platelet count secondary to increased platelet destruction or impaired thrombopoiesis by anti-thromboycte antibodies. ... -
Wwox Gen İfadesinin Kronik Lenfositik Lösemi İle İlişkisi
Amaç: WW alanı içeren oksidoredüktaz (WWOX) geni kromozom 16q23.3-q24.1 bölgesinde bulunmaktadır ve yaygın kromozomal frajilbölge, FRA16D, içermektedir. WWOX geni 46 kDa moleküler ağırlığında WWOX tümör baskılayıcı proteini ... -
Yüksek Riskli Diffüz Büyük B Hücreli Lenfoma Olgularında DA-EPOCH-R Deneyimi
Akpınar, Seval; Turgut, Burhan (2022)Amaç: Çalışmamızda yeni tanı, yüksek riskli diffüz büyük B-hücreli lenfoma (DBBHL) olgularında doz ayarlanmış EPOCH-R (DA-EPOCH-R) rejiminin sağkalım parametreleri üzerine etkisini araş- tırmayı amaçladık. Hastalar ve ...