Yazar "Göçmez, Semil Selcen" için listeleme
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Agmatine, a metabolite of L-arginine, reverses scopolamine-induced learning and memory impairment in rats
Utkan, Tijen; Göçmez, Semil Selcen; Regunathan, Soundararajan; Arıcıoğlu, Feyza (Pergamon-Elsevier Science Ltd, 2012)Agmatine (1-amino-4-guanidino-butane), a metabolite of L-arginine through the action of arginine decarboxylase, is a novel neurotransmitter. In the present study, effects of agmatine on cognitive functions have been evaluated ... -
Anti-inflammatory and ultrastructural effects of Turkish propolis in a rat model of endotoxin-induced uveitis
Erturkuner, Salime Pelin; Sarac, Elif Yaprak; Göçmez, Semil Selcen; Ekmekci, Hakan; Öztürk, Zeynep Banu; Seckin, İsmail; Keskinbora, Kadircan Hıdır; Sever, Özkan (Via Medica, 2016)Introduction. Experimental animal models of acute uveitis, an inflammatory eye disease, can be established via endotoxin-induced inflammation. Propolis, a natural substance collected by honeybees from buds and tree exudates, ... -
Beneficial effects of resveratrol on scopolamine but not mecamylamine induced memory impairment in the passive avoidance and Morris water maze tests in rats
Gacar, Nejat; Mutlu, Oğuz; Utkan, Tijen; Çelikyurt, İpek Komşuoğlu; Göçmez, Semil Selcen; Ulak, Guner (Pergamon-Elsevier Science Ltd, 2011)Resveratrol (3,5,4-trihydroxy-trans-stilbene), which is found in grapes and red wine has been shown to protect neuronal cells with its antioxidant activity, improve memory function in dementia and reverse acetylcholine ... -
Chronic administration of fluoxetine impairs neurogenic and endothelium-dependent relaxation of the rabbit corpus cavernosum smooth muscle
Göçmez, Semil Selcen; Utkan, Tijen; Gacar, Nejat; Sarıoğlu, Yusuf (Elsevier, 2011)Antidepressants, including selective serotonin reuptake inhibitors (SSRIs), cause erectile dysfunction: however, the mechanism by which they cause erectile function is unclear. We investigated the reactivity of the corpus ... -
Chronic administration of imipramine but not agomelatine and moclobemide affects the nitrergic relaxation of rabbit corpus cavernosum smooth muscle
Göçmez, Semil Selcen; Utkan, Tijen; Gacar, Nejat (Elsevier, 2013)Sexual dysfunction is a common and underestimated effect of antidepressants. However, the mechanism by which these drugs cause erectile dysfunction is unclear. We investigated the reactivity of the corpus cavernosum of ... -
A comparison of the effects of different classes of antidepressants on penile constitutive nitric oxide synthase of male rats
Yazır, Yağız Alp; Göçmez, Semil Selcen; Utkan, Tijen; Gacar, Nejat; Arıcıoğlu, Feyza (Elsevier Science Bv, 2012)[No Abstract Available] -
The effect of a selective neuronal nitric oxide synthase inhibitor 3-bromo 7-nitroindazole on spatial learning and memory in rats
Göçmez, Semil Selcen; Yazir, Yusufhan; Şahin, Deniz; Karadenizli, Sabriye; Utkan, Tijen (Pergamon-Elsevier Science Ltd, 2015)Since the discovery of nitric oxide (NO) as a neuronal messenger, its way to modulate learning and memory functions is subject of intense research. NO is an intercellular messenger in the central nervous system and is ... -
Effect of harmane, an endogenous beta-carboline, on learning and memory in rats
Çelikyurt, İpek Komşuoğlu; Utkan, Tijen; Göçmez, Semil Selcen; Hudson, Alan; Arıcıoğlu, Feyza (Pergamon-Elsevier Science Ltd, 2013)Our aim was to investigate the effects of acute harmane administration upon learning and memory performance of rats using the three-panel runway paradigm and passive avoidance test. Male rats received harmane (2.5, 5, and ... -
Effect of resveratrol on BDNF in a chronic unpredictable mild stress model: an immunohistochemical study
Yazır, Y.; Göçmez, Semil Selcen; Utkan, Tijen; Kurnaz, S.; Gacar, Nejat; Arıcıoğlu, Feyza (Elsevier Science Bv, 2012)[No Abstract Available] -
Effect of resveratrol on penile neuronal and endothelial nitric oxide synthase expression in chronic unpredictable mild stress depression model
Yazır, Yağız Alp; Demirtaş Şahin, Tuğçe; Göçmez, Semil Selcen; Utkan, Tijen; Gacar, Nejat (Elsevier Science Bv, 2015)[No Abstract Available] -
Effects of chronic etanercept, a TNF-alpha inhibitor, on cognitive deficits in diabetic rats
Göçmez, Semil Selcen; Utkan, Tijen; Karson, A.; Bayramgurler, D. (Elsevier Science Bv, 2013)[No Abstract Available] -
Effects of chronic etanercept, a TNF-alpha inhibitor, on cognitive dysfunction in cafeteria diet-fed rats
Demirtaş, T.; Utkan, Tijen; Göçmez, Semil Selcen; Karson, A. (Elsevier Science Bv, 2015)[No Abstract Available] -
Effects of chronic low- and high-dose ethanol intake on the nitrergic relaxations of corpus cavernosum and penile nitric oxide synthase in the rabbit
Yazır, Y.; Göçmez, Semil Selcen; Utkan, Tijen; Komşuoğlu Çelikyurt, I.; Gacar, Nejat; Sarıoğlu, Y. (Nature Publishing Group, 2012)Epidemiological evidence showed that chronic ethanol consumption is a major risk factor in the development of impotence. The present study investigated the effects of carbachol-, electrical field stimulation (EFS)-, sodium ... -
Effects of chronic treatment with fluoxetine, moclobemide and agomelatine on rat isolated thoracic aorta
Göçmez, Semil Selcen; Özer, Cengiz; Şahin, D.; Karadenizli, Sabriye; Utkan, Tijen (Elsevier Science Bv, 2013)[No Abstract Available] -
Effects of resveratrol on age-related changes in adrenomedullary catecholamine biosynthesis
Göçmez, Semil Selcen; Whidden, Melissa A.; Kirichenko, Nataliya; Erdos, Benedek; Sakarya, Yasemin; Funeus, Weedley; Tumer, Nihal (Federation Amer Soc Exp Biol, 2011)[No Abstract Available] -
Effects of resveratrol on scopolamine and mecamylamine induced memory impairment in rats
Gacar, Nejat; Utkan, Tijen; Mutlu, Oğuz; Göçmez, Semil Selcen; Çelikyurt, İpek Komşuoğlu; Ulak, G. (Elsevier Science Bv, 2010)[No Abstract Available] -
Evidence for the involvement of neuronal nitric oxide synthase and soluble guanylate cyclase on cognitive functions in rats
Komsuoglu-Çelikyurt, Ipek; Göçmez, Semil Selcen; Mutlu, Oğuz; Gacar, Nejat; Arıcıoğlu, Feyza; Utkan, Tijen (Pergamon-Elsevier Science Ltd, 2011)Aims: The influence of 3-bromo-7-nitroindazole (3-Br 7-NI), a potent and selective neuronal nitric oxide synthase (nNOS) inhibitor, and [1H-[1,2,4]-oxadiazole[4,3a]-quinoxaline-1-one] (ODQ), a highly selective, irreversible ... -
P.4.c.003 Resveratrol shows vasoprotective effect in an unpredictable chronic mild stress model of depression in rats
Göçmez, Semil Selcen; Gacar, G.; Yazir, Y.; Utkan, Tijen; Gacar, Nejat (Elsevier Science Bv, 2014)[No Abstract Available] -
Protective effects of an extract of propolis in scopolamine-induced cognitive impairment in rats
Göçmez, Semil Selcen; Demirtaş, T.; Aksoz, E.; Utkan, Tijen; Gacar, Nejat (Elsevier Science Bv, 2015)[No Abstract Available] -
Protective effects of metformin in scopolamine-induced cognitive impairment in rats
Aksöz, Elif; Göçmez, Semil Selcen; Demirtaş, Tuğçe; Utkan, Tijen (Elsevier Science Bv, 2015)[No Abstract Available]