Çelik, Ali CihanÖztürk, FundaErden, Pınar EsraKaçar, CerenKılıç, Esma2022-05-112022-05-1120151040-03971521-4109https://doi.org/10.1002/elan.201500180https://hdl.handle.net/20.500.11776/7187Amperometric lactate biosensor based on a carbon paste electrode modified with benzo[c]cinnoline and multiwalled carbon nanotubes is reported. Incorporation of benzo[c] cinnoline acting as a mediator and multiwalled carbon nanotubes providing a conduction pathway to accelerate electron transfer due to their excellent conductivity into carbon paste matrix resulted in a high performance lactate biosensor. The resulting biosensor exhibited a fast response, high selectivity, good repeatability and storage stability. Under the optimal conditions, the enzyme electrode showed the detection limit of 7.0 x 10(-8) M with a linear range of 2.0 x 10(-7) M-1.1 x 10(-4) M. The usefulness of the biosensor was demonstrated in serum samples.en10.1002/elan.201500180info:eu-repo/semantics/closedAccessAmperometrybenzo[c]cinnolineL-lactateredox mediatormultiwalled carbon nanotubesL-Lactic AcidElectrochemical BiosensorFilm ElectrodesOxidaseCompositeGlucoseImmobilizationDehydrogenaseGrapheneBehaviorArticle271228202828Q2WOS:0003683403000172-s2.0-84954385912Q2