Açar, SamiKarabağ, SevilSasan, HadiAydın, CanKüçükmetin, Nurten Türkel2024-10-292024-10-2920232147-9291https://doi.org/10.5336/caserep.2023-97185https://search.trdizin.gov.tr/tr/yayin/detay/1261314https://hdl.handle.net/20.500.11776/13888McKittrick-Wheelock syndrome (MKWS) is characterised by electrolyte abnormalities such as secretory diarrhoea with mucus, hypokalemia, hyponatremia, dehydration from fluid loss, and/or prerenal acute renal failure. Depending on the severity of clinical symptoms, syn- cope may happen. This is caused on by a massive hypersecretory villous adenoma, which is typically seen in the rectum or rectosigmoid region. If untreated, this condition could worsen and result in death, so a careful evaluation is necessary. Depending on the size, loc ation, and level of involvement in the colorectal wall, the villous adenoma causing the condition may be treated by endoscopic, laparoscopic, or open surgery. This article's goal is to demonstrate an assessed case of syncope that underwent examinations and was ultimately classified as MKWS.en10.5336/caserep.2023-97185info:eu-repo/semantics/openAccessMcKittrick-Wheelock syndromeHypokalemiadiarrheasyncopevillous adenomaArticle3141301341261314