Boyuk, BanuOkuturlar, YıldızUludag, ErdoğanAtalay, HandeGüzel, SavaşÇelebi, Aslan2022-05-112022-05-1120182602-30322602-3040https://doi.org/10.17826/cumj.340257https://hdl.handle.net/20.500.11776/9221Purpose: Latest studies suggest that C-peptide may have a beneficial biological role on diabetic nephropathy. The aim of this study is to analyze whether there is an association between serum C-peptide level and microalbuminuria in type 2 diabetes mellitus (T2DM). Materials and Methods: We enrolled 184 T2DM patents and 46 healthy subjects in this study. Clinical variables and routine biochemical tests along with serum C peptide levels measured after an overnight fasting. Serum C peptide levels between 1.1 and 4.4 accepted as normal. 24-hour-urine samples were investigated and values between 30-300mgwere recorded as microalbuminuria. Pearson correlation analysis were used to determine associations between continuous variables. Results: C peptide levels were not significantly difference in T2DM patients compared to healthy controls. Serum C peptide levels showed positive correlation with insulin and microalbminuria with the Pearson correlation analysis. However, there was no significant association between other variables and C peptide levels. Conclusion: A correlation was found between microalbuminuria and serum C-peptide in this present study. Findings suggest C-peptide is related with renal complications of T2DM patients.en10.17826/cumj.340257info:eu-repo/semantics/openAccessC peptidemicroalbuminuriadiabetesGlomerular-Filtration-RateRenal-FunctionReactive ProteinPlasmaArticle4315661N/AWOS:000431893600009