Synthesis of Novel Pyrrolo[3,2-c]carbazole and Dipyrrolo[3,2-c: 2 ',3 '-g]carbazole Derivatives

Şengül, İbrahim FazılAstarcı, ErhanKandemir, Hakan2022-05-112022-05-1120160936-52141437-2096https://doi.org/10.1055/s-0035-1560601https://hdl.handle.net/20.500.11776/7239Pyrrolocarbazole and dipyrrolocarbazoles have been synthesized via the Hemetsberger indole synthesis, starting from 9-ethyl carbazole-3-carbaldehyde and 9-ethylcarbazole-3,6-dicarbaldeyde, respectively. The pyrrolocarbazole structures were confirmed through H-1 NMR, C-13 NMR, IR, mass spectrometry and single crystal X-ray diffraction techniques. The targeted compounds showed potent in vitro cytotoxicity against human colon cancer HT29 cells.en10.1055/s-0035-1560601info:eu-repo/semantics/closedAccesscarbazolepyrrolocarbazoleHemetsberger indolizationHT29 cellscyctotoxicityInhibitorsSynthesis of Novel Pyrrolo[3,2-c]carbazole and Dipyrrolo[3,2-c: 2 ',3 '-g]carbazole DerivativesArticle27812771281Q2WOS:000375004700028