Aydın, Elif BurcuSezgintürk, Mustafa Kemal2022-05-112022-05-1120211040-0397https://doi.org/10.1002/elan.202060603https://hdl.handle.net/20.500.11776/5100A highly sensitive impedimetric immunosensor for the determination of interleukin 8 (IL 8) cancer biomarker was fabricated via simple fabrication process. A silane agent with isocyanate groups, 3-(triethoxysilyl)propyl isocyanate (IPTES), were utilized for binding of IL 8 antigen specific antibodies and self-assembled on the fluorine tin oxide (FTO) substrate with a standard silanization chemistry. Under optimum experimental conditions, the designed immunosensor had a wide linear detection range of 0.02–4 pg/mL, a low limit of detection of 11.9 fg/mL and a high sensitivity of 4.42 k? pg?1 mL cm?2. The designed biosensor displayed high reproducibility and repeatability, good selectivity against interference biomarkers. © 2021 Wiley-VCH GmbHen10.1002/elan.202060603info:eu-repo/semantics/closedAccess3-(triethoxysilyl)propyl isocyanateDisposable electrodeFluorine tin oxideInterleukin 8Fabrication of Electrochemical Immunosensor for Detection of Interleukin 8 Biomarker via Layer-by-layer Self-assembly Process on Cost-effective Fluorine Tin Oxide ElectrodeArticle33615961605Q3WOS:0006318543000012-s2.0-85102957235Q2