Erdem, HasanAktimur, RecepÇetinkunar, SüleymanReyhan, EnverGökler, CihanIrkorucu, OktaySözen, Selim2022-05-112022-05-1120151940-5901https://hdl.handle.net/20.500.11776/8144Background: Diagnosis of acute appendicitis remains to be challenging with up to 30% negative exploration rates. In addition to careful clinical history and physical examination, we still need easily applicable, cheap and effective biomarker. Patients and methods: A retrospective case-controlled study was designed in two groups, both containing 100 patients, acute appendicitis and control. Leukocyte count, neutrophil percentage, platelet count and meal platelet volume (MPV) were compared. Results: MPV values for acute appendicitis and control groups were 7.4 +/- 0.9 fL (5.6-10.6) and 9.1 +/- 1.6 fL (5.1-13.1). For the diagnosis of acute appendicitis, ROC analysis revealed 74% sensitivity and 75% specificity for a cut-off value of 7.95 fL of MPV, however, the diagnostic value of leukocyte count and/or neutrophil ratio was superior. Conclusion: Our results suggest that, MPV value is an important parameter in the diagnosis of acute appendicitis, but in terms of sensitivity and specificity, leukocyte count and/or neutrophil percentage is superior.eninfo:eu-repo/semantics/closedAccessAcute appendicitismean platelet volumesensitivityspecificityInflammatory-Bowel-DiseaseIndicatorAccuracyMarkerArticle8112911295Q4WOS:0003498972001612-s2.0-8492299870625785128N/A