Urgut, O. S.Öztürk, İbrahim İsmetBanti, Christina N.Kourkoumelis, NikolaosManoli, MariaTasiopoulos, Anastasios J.Hadjikakou, Sotiris K.2022-05-112022-05-1120160020-16931873-3255https://doi.org/10.1016/j.ica.2015.12.028https://hdl.handle.net/20.500.11776/7218Three new antimony(III) iodide complexes with the N,N-diethylcarbamodithioic acid of formulae {[(SbI(Et2DTC)(2))(I-2)](n)} (1), {[(Sb(Et2DTC)(2))(4) (SbI6) (I-3)](n)} (2) and {[SbI(Et2DTC)(2)](2)} (3), (Et2DTCH: N,N-diethylcarbamodithioic acid, C5H11NS2) were synthesized from the reaction of antimony(III) iodide with tetraethylthiuram disulfide in 1: 1 stoichiometry. The complexes 1-3 were characterized by melting point, elemental analysis, FT-IR spectroscopy, Raman spectroscopy, H-1, C-13 NMR spectroscopy and Thermal Gravimetry-Differential Thermal Analysis (TG-DTA). Moreover, crystal structures of complexes 1-3 were determinated with single crystal X-ray diffraction analysis. Complexes 1-3 derived from ligand reduction with concomitant degradation of the tetraethylthiuram disulfide to dithiocarbamates. Complexes 1 and 2 are polymer but complex 3 is dimmer. Complex 1 consists of two residues, [SbI (Et2DTC)(2)] and [I-2], while 2 consists of three residues, four cationic [Sb(Et(2)dtc)(2)](+), one [SbI6](3-) and one [I-3](-) counter anion. Complexes 1-3 were evaluated for their in vitro cytotoxic activity against human breast adenocarcinoma (MCF-7) and human cervix adenocarcinoma (HeLa) cells. Structure Activity Relationship (SAR) studies reveal that the high activity of the complexes is positively correlated with the low H-all atoms intermolecular contacts. (C) 2016 Elsevier B.V. All rights reserved.en10.1016/j.ica.2015.12.028info:eu-repo/semantics/closedAccessAntimony(III) complexesCrystal structuresN,N-diethylcarbamodithioic acidCytotoxicityStructure Activity Relationship (SAR)Structural-CharacterizationIn-VitroMolecular-StructureDiphenylantimony(Iii) DerivativesCoordination ChemistryCrystal-StructureThiuram SulfidesHalide-ComplexesDithiocarbamateBismuth(Iii)Article443141150Q2WOS:0003690709000202-s2.0-84954475947Q2