Güzel, Eda ÇelikFidan, ÇiğdemGüzel, SavaşPaketci, Cem2022-05-112022-05-1120172602-30322602-3040https://doi.org/10.17826/cutf.323816https://hdl.handle.net/20.500.11776/5258Purpose: Our aim is to evaluate the relationship between C-reactive protein (CRP)/mean platelet volume (MPV) ratio and white blood cell (WBC)/mean platelet volume (MPV) ratio and diagnosis and disease severity in children with community-acquired pneumonia (CAP). Material and Methods: 60 patients with CAP including 33 mild-moderate (Group 1) and 27 severe pneumonia (Group 2) and 30 healthy children were examined for routine blood test. WBC, MPV, neuotrophile/lymhocyte ratio (NLR), CRP, WBC/MPV, CRP/MPV values were recorded on each patient and healthy groups. Result: CRP/MPV, WBC/MPV, NLR and plateletcrit values were significantly higher in patients group than controls, while MPV value is not correlated between patient and control groups. WBC, NLR, WBC/MPV, CRP/MPV and CRP values were higher in the Group 2 compared to Group 1. CRP/MPV and WBC/MPV were positively correlated with duration of symptoms in the CAP. The area under ROC curve of CRP, WBC and WBC/MPV in diagnosing CAP was significant (0.801, 0.761 and 0.731). Also the area under ROC curve of Group 2 in CRP/MPV and CRP in diagnosing CAP was significant (0.733, 0.708). Conclusion: CRP/MPV and WBC/MPV ratio may be used a marker in the evaluation of CAP diagnosis and CRP/MPV ratio can be good marker prediction of disease activity.tr10.17826/cutf.323816info:eu-repo/semantics/openAccessPneumoniaC-reactive proteinwhite blood cellmean platelet volumedisease severityBlood-Cell CountClinical CharacteristicsNeutrophil/LymphocyteMortalityBacterialIndexesMarkerC-reactive protein (CRP)/mean platelet volume (MPV) ratio as a new biomarker for community-acquired pneumonia in childrenArticle423451458N/AWOS:000414860000007