Facile and efficient method for Zn(OTf)2 catalyzed synthesis of isocoumarin derivatives and their antioxidant properties

Uludag, NesimiNevarsa, Alev Orhan2024-10-292024-10-2920230019-5103https://doi.org/10.56042/ijc.v62i4.429https://hdl.handle.net/20.500.11776/14848In this research, the corresponding isocoumarin derivatives have been synthesized by tandem intramolecular cyclization of methyl 2-(phenylethynyl)benzoate 1 with ethyl acrylate. This process involves the synthesis of compounds 3-9 from compound 1 and 2 in one-pot reaction and zinc triflate as catalyst. The antioxidant properties of the synthesized isocoumarin have also been investigated by DPPH method.en10.56042/ijc.v62i4.429info:eu-repo/semantics/openAccessIsocoumarinZinc triflateAntioxidant propertiesBiological activitiesPharmaceutical propertiesFacile and efficient method for Zn(OTf)2 catalyzed synthesis of isocoumarin derivatives and their antioxidant propertiesArticle624350354Q4WOS:0009763323000062-s2.0-85176257095N/A