Şabudak, TemineOrak, Hakime HülyaGülen, DumrulÖzer, MerveÇalışkan, HilmicanBahrisefit, İlaydaCabi, Evren2022-05-112022-05-1120170019-5464https://doi.org/10.5530/ijper.51.3s.48https://hdl.handle.net/20.500.11776/5162Background: Cirsium vulgare (Savi) Ten; belongs the Asteraceae family and has common uses in some countries folk medicine. Objective: In this study, the determination of some antioxidant and antimicrobial properties of C. vulgare which is wild-grown from Turkey is aimed. Methods: Crude extracts of plants were obtained by using n-hexane, diethyl ether, ethyl acetate and methanol as solvent. Total phenolic content (TPC) and DPPH (2,2-diphenyl 2,2-diphenyl-1 picrylhydrazyl picrylhydrazyl) scavenging activity were determined in extracts. The antibacterial activity was tested against Staphylococcus aureus (ATCC 43300), Escherichia coli (ATCC 35218), Bacillus subtilis (NRRL NRS-744) and Pseudomonas aeruginosa (ATCC 27853). Results: The TPC and DPPH activities of extracts revealed significant differences by following sequence MeOH > diethyl ether > EtOAc > n-hexane. The highest inhibition effect of C. vulgare was found on P. aeruginosa. Conclusion: Results presented that C. vulgare can be researched for future investigations for isolations of biologically active compounds, where some of their characteristics are expected to be contribute to the natural compounds in pharmaceutical industry.en10.5530/ijper.51.3s.48info:eu-repo/semantics/openAccessCirsium vulgarePhenolic contentDPPH activityAntibacterial activityP. aeruginosaExtractsLeavesArticle513S363S367Q4WOS:0004185491000082-s2.0-85032958646Q3