Çetinkol, T.Öztürk, FundaErden, Pınar Esra2022-05-112022-05-1120192149-0120https://doi.org/10.18596/jotcsa.450793https://hdl.handle.net/20.500.11776/7280Electrochemical behavior of naphazoline hydrochloride on a carbon paste electrode that was modified with aluminium oxide nanoparticles (Al2O3NPs) was investigated in a Britton-Robinson (BR) buffer (pH 7.0) using various voltammetric techniques. The results support the presence of an irreversible and diffusion-controlled electrochemical oxidation signal of naphazoline hydrochloride which is approximately at 0.9 V vs. Ag/AgCl. A selective, accurate, and simple square-wave anodic adsorptive stripping voltammetric method was proposed for naphazoline hydrochloride detection. The linear response was within the range of 5.0 × 10-8-3.0 × 10-5 mol L-1 with a detection limit of 2.6 × 10-9 mol L-1 (0.642 ?g L-1). In addition, the proposed method was also utilized for naphazoline hydrochloride determination in human serum sample. © 2019, Turkish Chemical Society. All rights reserved.en10.18596/jotcsa.450793info:eu-repo/semantics/openAccessAluminum oxide nanoparticlesDoping agentElectrochemical techniquesHuman serumNaphazolineArticle6179882-s2.0-85070516381Q4