Tuberculosis osteomyelitis of the tibia mimicking Brodie abscess: A case report and review of the literature

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dc.authorid0000-0003-3416-5666
dc.authorid0000-0002-4693-3784
dc.authorid0000-0001-6576-1802
dc.authorid0000-0001-9827-8892
dc.authorwosidsari, abdulkadir/ABH-3293-2021
dc.authorwosidsayiner, hakan sezgin/V-9889-2017
dc.authorwosidçetin, mehmet ümit/AAA-4905-2022
dc.authorwosidDinçel, Yaşar Mahsut/AAB-8340-2019
dc.authorwosiddinçel, yaşar mahsut/AAF-9455-2019
dc.authorwosidsari, abdulkadir/AAF-3143-2021
dc.contributor.authorSarı, Abdulkadir
dc.contributor.authorDinçel, Yaşar Mahsut
dc.contributor.authorErdoğdu, İbrahim Halil
dc.contributor.authorSayıner, Hakan Sezgin
dc.contributor.authorAğır, İsmail
dc.contributor.authorÇetin, Mehmet Ümit
dc.date.accessioned2022-05-11T14:36:14Z
dc.date.available2022-05-11T14:36:14Z
dc.date.issued2019
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Ortopedi ve Travmatoloji Ana Bilim Dalı
dc.description.abstractBackground: Tuberculosis osteomyelitis is rarely seen in the diaphyseal bones. It may be confused with Brodie's abscess due to similar clinical, radiological and laboratory findings. Late diagnosis of the disease causes bone destruction. Tuberculosis osteomyelitis of the bone is a rare condition caused by the Mycobacterium tuberculosis. Its incidence has increased in Western countries in recent years due to HIV infection, increasing elderly population and emerging resistant strains. The slow progress of tuberculous osteomyelitis, due to lack of significant elevations in the laboratory values and changes in the radiographic appearance, often leads to confusion with the subtypes of subacute osteomyelitis, defined as Brodie's abscess. These two low-virulence clinical cases often lead to delays in diagnosis and progressive bone destruction. Case presentation: We report a 65-year-old male patient who presented to our clinic with pain, swelling and sensitivity in the left leg. Diagnosed with infection in the tibia, the patient had undergone antibiotherapy. However, the patient's symptoms were not resolved and we performed bone curettage and cementation. M. tuberculosis-specific DNA was detected by real-time polymerase chain reaction and the M. tuberculosis complex was produced from the perioperative samples. Conclusion: In conclusion, histopathological examination and polymerase chain reaction are essential before surgery of subacute and chronic osteomyelitis with atypical clinical, laboratory and radiological findings for early diagnosis and accurate treatment.
dc.identifier.doi10.1177/2050313X19869455
dc.identifier.issn2050-313X
dc.identifier.pmid31448121
dc.identifier.urihttps://doi.org/10.1177/2050313X19869455
dc.identifier.urihttps://hdl.handle.net/20.500.11776/8418
dc.identifier.volume7
dc.identifier.wosWOS:000483537200001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.institutionauthorSarı, Abdulkadir
dc.institutionauthorDinçel, Yaşar Mahsut
dc.institutionauthorÇetin, Mehmet Ümit
dc.language.isoen
dc.publisherSage Publications Inc
dc.relation.ispartofSage Open Medical Case Reports
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBrodie's abscess
dc.subjectreal-time polymerase chain reaction
dc.subjecttibial diaphyseal osteomyelitis
dc.subjecttuberculous osteomyelitis
dc.titleTuberculosis osteomyelitis of the tibia mimicking Brodie abscess: A case report and review of the literature
dc.typeReview Article

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