Association between Vitamin D Level and Microvascular Complications in Patients with Type 2 Diabetes

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dc.authorid0000-0001-7213-9624
dc.authorid0000-0001-7213-9624
dc.authorwosiderman, hande/AAZ-7697-2021
dc.authorwosiderman, hande/AAP-6507-2021
dc.authorwosidAyar, Yavuz/O-9948-2015
dc.authorwosidBOYUK, BANU/ABA-7026-2021
dc.contributor.authorBoyuk, Banu
dc.contributor.authorAtalay, Hande
dc.contributor.authorDeğirmencioğlu, Şerife
dc.contributor.authorAltay, Murat
dc.contributor.authorGüzel, Savaş
dc.contributor.authorÇelebi, Asian
dc.contributor.authorAyar, Yavuz
dc.date.accessioned2022-05-11T14:42:06Z
dc.date.available2022-05-11T14:42:06Z
dc.date.issued2017
dc.departmentFakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyokimya Ana Bilim Dalı
dc.description.abstractObjectives: The aim of this study was to further investigate the prevalence of Vitamin D deficiency in diabetes mellitus (DM) patients, as well as the association between hypovitaminosis D and the microvascular complications of type 2 (T2) DM. Methods: This was a cross-sectional, case-control study of 206 T2DM patients and 34 healthy control subjects. Participants were evaluated for the presence of diabetic retinopathy, nephropathy, and neuropathy. Results: The level of serum 25-hydroxyvitamin D (25(OH) D) was significantly lower in the T2DM patients (11.16 +/- 3.99 ng/mL vs. 15.58 +/- 3.16 ng/mL; p<0.05). Furthermore, 2.7% of the patients were found to have retinopathy (n=53), 3.6% had neuropathy (n=65), and 29.1% of the patients had microalbuminuria (n=60). Although serum 25(OH) D levels were significantly lower in the presence of retinopathy and neuropathy (p<0.05 for both), no significant association between Vitamin D level and microalbuminuria was found. Conclusion: An inverse relationship between the circulating 25(OH) D level and the prevalence of retinopathy and neuropathy in T2DM patients was determined. However, there was no significant association between microalbuminuria and the 25(OH) D level.
dc.identifier.doi10.14744/ejmo.2017.69775
dc.identifier.endpage196
dc.identifier.issn2587-196X
dc.identifier.issue4en_US
dc.identifier.startpage190
dc.identifier.urihttps://doi.org/10.14744/ejmo.2017.69775
dc.identifier.urihttps://hdl.handle.net/20.500.11776/9220
dc.identifier.volume1
dc.identifier.wosWOS:000604211000002
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.institutionauthorGüzel, Savaş
dc.language.isoen
dc.publisherKare Publ
dc.relation.ispartofEurasian Journal of Medicine and Oncology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectMicrovascular complications
dc.subjecttype 2 diabetes
dc.subjectvitamin D deficiency
dc.subjectInsulin-Resistance
dc.subjectD Insufficiency
dc.subjectPeripheral Neuropathy
dc.subjectD Supplementation
dc.subjectD Deficiency
dc.subjectGlucose
dc.subjectRetinopathy
dc.subjectNephropathy
dc.subjectIslets
dc.subjectRisk
dc.titleAssociation between Vitamin D Level and Microvascular Complications in Patients with Type 2 Diabetes
dc.typeArticle

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