Investigation of Electrochemical Properties of Uric Acid at Carbon Paste Electrode with Aluminium Oxide Nanoparticles and Development of Voltammetric Method for its Determination in Serum

dc.contributor.authorÜnvert, Rüveyda
dc.contributor.authorÖztürk, Funda
dc.date.accessioned2024-10-29T17:50:00Z
dc.date.available2024-10-29T17:50:00Z
dc.date.issued2023
dc.departmentTekirdağ Namık Kemal Üniversitesi
dc.description.abstractThe electrochemical properties of uric acid (UA) were determined by cyclic voltammetry (CV) and square wave voltammetry (SWV) at a carbon paste electrode modified with aluminum oxide nanoparticles (Al2O3NP/CPE) in 0.05 M pH 5.0 phosphate buffer. The adsorption properties of the molecule on Al2O3NP/CPE were investigated and the number of electrons transferred in the electrode reaction was calculated. A new voltammetric method for the determination of UA in human serum was also proposed. The linear operating range and limit of detection (LOD) of the method were found to be 0.1µM-230 µM and 0.1µM, respectively. The developed method for UA in serum showed high reliability, reproducibility, accuracy and precision.
dc.identifier.doi10.15671/hjbc.1225829
dc.identifier.endpage200
dc.identifier.issn1303-5002
dc.identifier.issn2687-475X
dc.identifier.issue2en_US
dc.identifier.startpage191
dc.identifier.trdizinid1200439
dc.identifier.urihttps://doi.org/10.15671/hjbc.1225829
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1200439
dc.identifier.urihttps://hdl.handle.net/20.500.11776/12689
dc.identifier.volume51
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofHacettepe Journal of Biology and Chemistry
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectUric acid
dc.subjectsensor
dc.subjectvoltammetric method
dc.subjectaluminum oxide nanoparticles
dc.titleInvestigation of Electrochemical Properties of Uric Acid at Carbon Paste Electrode with Aluminium Oxide Nanoparticles and Development of Voltammetric Method for its Determination in Serum
dc.typeArticle

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