Childhood asthma and vitamin D deficiency in Turkey: is there cause and effect relationship between them?

Basit Öğe Kaydı
dc.authorid0000-0002-3535-5704
dc.authorwosidMutlu, Levent Cem/AAZ-5186-2020
dc.contributor.authorUysalol, Metin
dc.contributor.authorMutlu, Levent Cem
dc.contributor.authorSaraçoğlu Varol, Gamze
dc.contributor.authorKarasu, Erkut
dc.contributor.authorGüzel, Savaş
dc.contributor.authorKayaoğlu, Semra
dc.contributor.authorUzel, Nedret
dc.date.accessioned2022-05-11T14:09:56Z
dc.date.available2022-05-11T14:09:56Z
dc.date.issued2013
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Göğüs Cerrahisi Ana Bilim Dalı
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Halk Sağlığı Ana Bilim Dalı
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı
dc.departmentFakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyokimya Ana Bilim Dalı
dc.description.abstractBackground: Epidemiological studies show that vitamin D deficiency and insufficiency are common worldwide and associated with many diseases including asthma. Our aim was to evaluate vitamin D insufficiency and its clinical consequences. Methods: This cross-sectional study was carried out on 170 children consisted of 85 who were asthmatic and 85 who were not, aged 2 to 14 years in Tekirdag, Turkey, from September 2009 to May 2010. Children's basal serum D vitamin levels were determined, and their eating habits, vitamin D intake, exposure to sunlight and use of health services during the previous year were investigated. The severity of asthma and levels of asthma control were assessed according to the Global Initiative for Asthma guidelines. Results: The difference between mean vitamin D levels in the asthmatic group (mean +/ SD) 16.6 +/ 8.5 ng/mL and the healthy control group (mean +/- SD) 28.2 +/- 19.5 ng/mL was found to be statistically significant (p < 0.001). Children in the asthma group had less exposure to sunlight and ate a diet less rich in vitamin D (p < 0.001). A significant difference was observed between the groups regarding the frequency of respiratory tract infections leading to emergency unit admissions and number of hospitalizations (p < 0.001). It was also shown that a decrease in vitamin D level increased the severity of asthma (p < 0.001) and decreased the frequency of controlled asthma (p = 0.010). Conclusion: This study has demonstrated the correlation between plasma 25 (OH) D levels and childhood asthma. Evidently, this relationship being influenced by multiple factors other than vitamin D, further studies should be conducted to explore the interrelation between all such factors.
dc.identifier.doi10.1186/1824-7288-39-78
dc.identifier.issn1720-8424
dc.identifier.issn1824-7288
dc.identifier.pmid24330502
dc.identifier.urihttps://doi.org/10.1186/1824-7288-39-78
dc.identifier.urihttps://hdl.handle.net/20.500.11776/5209
dc.identifier.volume39
dc.identifier.wosWOS:000331896100001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.institutionauthorMutlu, Levent Cem
dc.institutionauthorSaraçoğlu Varol, Gamze
dc.institutionauthorKarasu, Erkut
dc.institutionauthorGüzel, Savaş
dc.language.isoen
dc.publisherBmc
dc.relation.ispartofItalian Journal of Pediatrics
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectChildren
dc.subjectSeverity
dc.subjectManagement
dc.subjectRisk
dc.titleChildhood asthma and vitamin D deficiency in Turkey: is there cause and effect relationship between them?
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
5209.pdf
Boyut:
776.51 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Tıp Fakültesi Koleksiyonu