Radiotherapy-Related Tumour Lysis Syndrome in a Patient with Metastatic Adenocarcinoma of Unknown Origin

Basit Öğe Kaydı
dc.contributor.authorBayrakçı, Nergiz
dc.contributor.authorÖzkayar, N.
dc.contributor.authorÇağlayan, O.
dc.contributor.authorDede, F.
dc.date.accessioned2023-04-20T08:04:12Z
dc.date.available2023-04-20T08:04:12Z
dc.date.issued2022
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı
dc.description.abstractTumour lysis syndrome (TLS) is a rare but serious complication of cancer treatment. It is generally seen in patients with high tumour load or chemosensitive tumour after chemotherapy and is more common with haematological malignancies like leukaemia and lymphoma when compared to solid tumours. TLS occurring after radiotherapy (RT) in patients with solid tumours is very rare. We aimed to present TLS seen after RT for a vertebral tumoral mass in a patient with metastatic adenocarcinoma of unknown origin. A 78-year-old woman, who was diagnosed with adenocarcinoma of unknown origin, was hospitalized to undergo palliative RT for the vertebral mass. On the 1st day, 4 mg q6hour perioral dexamethasone was started. 300 cGy per session RT started on the 2nd day of hospitalization. After the fifth session of RT (after a total dose of 15 Gy), she developed TLS complicated with acute kidney injury requiring renal replacement therapy and she was successfully treated by haemodialysis. Close monitoring, even in patients with low risk for TLS and early administration of preventive modalities should be kept in mind.
dc.identifier.doi10.7727/wimj.2015.350
dc.identifier.endpage525
dc.identifier.issn0043-3144
dc.identifier.issn2309-5830
dc.identifier.issue7en_US
dc.identifier.startpage523
dc.identifier.urihttps://doi.org/10.7727/wimj.2015.350
dc.identifier.urihttps://hdl.handle.net/20.500.11776/11011
dc.identifier.volume69
dc.identifier.wosWOS:000794032100012
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.institutionauthorBayrakçı, Nergiz
dc.language.isoen
dc.publisherUniv West Indies Faculty Medical Sciences
dc.relation.ispartofWest Indian Medical Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectRadiotherapy
dc.subjectSolid Tumour
dc.subjectTumour Lysis Syndrome
dc.titleRadiotherapy-Related Tumour Lysis Syndrome in a Patient with Metastatic Adenocarcinoma of Unknown Origin
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Tıp Fakültesi Koleksiyonu