The comparison of the suture materials on intestinal anastomotic healing: an experimental study

Küçük Resim Yok

Tarih

2023

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

BACKGROUND: This experimental comparative study was to evaluate the local effects of three different suture materials on in- testinal anastomosis healing. METHODS: Ethical approval was obtained from the University Ethical Committee (E-60758568-020-176720). A prospective, ex- perimental comparative analysis was conducted on 24 rats. They were divided into three equal groups; Group 1 underwent colonic anastomosis with Vicryl suture material, Group 2 underwent colonic anastomosis with polypropylene suture; and Group 3 underwent colonic anastomosis with polydioxanone (PDS) suture. The second operation underwent the 7th post-operative day. Adhesion score, anastomotic leakage, anastomotic bursting pressure, hydroxyproline levels, and histopathologic examination were evaluated. RESULTS: All animals survived, and no leakage, intestinal obstruction, or wound infection was observed during the experiment. The adhesion score was evaluated according to the Diamond classification and same in all groups. Median anastomotic bursting pressure was 125.75 mmHg (10–241) in the Vicryl group, 159.25 mmHg (113–190) in the polypropylene group, and 154.50 mmHg (20–212) in the PDS group. Hydroxyproline tissue concentrations were in the Vicryl group 1699.92±220.8 ng/mg (range: 1509.81–2186.47), in the polypropylene group 1126.24±607.12 ng/mg (range: 53.22–1815.63), and 1547.86±335.2 ng/mg (range: 973.66–1973.2) in PDS group. There was no difference among groups regarding the inflammatory response evaluated by histopathology. There was no statistical significance in all variables evaluated. CONCLUSION: This experimental study demonstrates that suture materials did not worsen tissue healing during intestinal anasto- mosis. Absorbable, slowly-absorbable, and non-absorbable suture materials could be used safely in every situation.

Açıklama

Anahtar Kelimeler

Animal experiments, anastomotic leak, Anastomotic healing, surgical anastomosis, suture techniques.

Kaynak

Ulusal Travma ve Acil Cerrahi Dergisi

WoS Q Değeri

Scopus Q Değeri

Cilt

29

Sayı

9

Künye