C-reactive protein (CRP)/mean platelet volume (MPV) ratio as a new biomarker for community-acquired pneumonia in children

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dc.authorid0000-0003-2520-6825
dc.authorid0000-0003-3587-6830
dc.authorwosidFidan, Cigdem/X-7070-2018
dc.authorwosidPaketci, Cem/A-1490-2018
dc.contributor.authorGüzel, Eda Çelik
dc.contributor.authorFidan, Çiğdem
dc.contributor.authorGüzel, Savaş
dc.contributor.authorPaketci, Cem
dc.date.accessioned2022-05-11T14:10:02Z
dc.date.available2022-05-11T14:10:02Z
dc.date.issued2017
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Aile Hekimliği Ana Bilim Dalı
dc.departmentFakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyokimya Ana Bilim Dalı
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı
dc.description.abstractPurpose: Our aim is to evaluate the relationship between C-reactive protein (CRP)/mean platelet volume (MPV) ratio and white blood cell (WBC)/mean platelet volume (MPV) ratio and diagnosis and disease severity in children with community-acquired pneumonia (CAP). Material and Methods: 60 patients with CAP including 33 mild-moderate (Group 1) and 27 severe pneumonia (Group 2) and 30 healthy children were examined for routine blood test. WBC, MPV, neuotrophile/lymhocyte ratio (NLR), CRP, WBC/MPV, CRP/MPV values were recorded on each patient and healthy groups. Result: CRP/MPV, WBC/MPV, NLR and plateletcrit values were significantly higher in patients group than controls, while MPV value is not correlated between patient and control groups. WBC, NLR, WBC/MPV, CRP/MPV and CRP values were higher in the Group 2 compared to Group 1. CRP/MPV and WBC/MPV were positively correlated with duration of symptoms in the CAP. The area under ROC curve of CRP, WBC and WBC/MPV in diagnosing CAP was significant (0.801, 0.761 and 0.731). Also the area under ROC curve of Group 2 in CRP/MPV and CRP in diagnosing CAP was significant (0.733, 0.708). Conclusion: CRP/MPV and WBC/MPV ratio may be used a marker in the evaluation of CAP diagnosis and CRP/MPV ratio can be good marker prediction of disease activity.
dc.identifier.doi10.17826/cutf.323816
dc.identifier.endpage458
dc.identifier.issn2602-3032
dc.identifier.issn2602-3040
dc.identifier.issue3en_US
dc.identifier.startpage451
dc.identifier.urihttps://doi.org/10.17826/cutf.323816
dc.identifier.urihttps://hdl.handle.net/20.500.11776/5258
dc.identifier.volume42
dc.identifier.wosWOS:000414860000007
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.institutionauthorGüzel, Eda Çelik
dc.institutionauthorFidan, Çiğdem
dc.institutionauthorGüzel, Savaş
dc.institutionauthorPaketci, Cem
dc.language.isotr
dc.publisherCukurova Univ, Fac Medicine
dc.relation.ispartofCukurova Medical Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectPneumonia
dc.subjectC-reactive protein
dc.subjectwhite blood cell
dc.subjectmean platelet volume
dc.subjectdisease severity
dc.subjectBlood-Cell Count
dc.subjectClinical Characteristics
dc.subjectNeutrophil/Lymphocyte
dc.subjectMortality
dc.subjectBacterial
dc.subjectIndexes
dc.subjectMarker
dc.titleC-reactive protein (CRP)/mean platelet volume (MPV) ratio as a new biomarker for community-acquired pneumonia in children
dc.typeArticle

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