Desquamative interstitial pneumonia: Risk factors, laboratory and bronchoalveolar lavage findings, radiological and histopathological examination, clinical features, treatment and prognosis
Yükleniyor...
Dosyalar
Tarih
2019
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Spandidos Publ Ltd
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Desquamative interstitial pneumonia is a type of smoking-associated major idiopathic interstitial pneumonia, which is characterized by accumulation of alveolar macrophages in alveolar lumens and septa and develops secondary to mainly active or passive exposure to cigarette smoke. Desquamative interstitial pneumonia mostly occurs in male smokers in association with non-specific symptoms responsive to steroid therapy and has a better prognosis than usual interstitial pneumonia. To date, no large-scale clinical studies have been performed on desquamative interstitial pneumonia patients. Factors responsible for the scarcity of data on the clinical course of this condition include the retrospective nature of the available information as well as its rare occurrence. Despite this, a general consensus exists as to the nature of its symptoms, association with smoking, age and gender distribution, findings of respiratory function tests, steroid responsivity and mortality. The objective of the present review article was to report on desquamative interstitial pneumonia and to describe its etiology, risk factors and clinical features, as well as the laboratory, bronchoalveolar lavage, radiological and histopathological findings, and the treatment and prognosis of affected patients.
Açıklama
Anahtar Kelimeler
desquamative interstitial pneumonia, idiopathic interstitial pneumonias, interstitial pneumonia, lung diseases, pulmonary, smoking, Idiopathic Pulmonary-Fibrosis, High-Resolution Ct, Respiratory Bronchiolitis, Lung-Disease, Hypersensitivity Pneumonitis, Natural-History, Recurrence, Patient, Biopsy, Classification
Kaynak
Experimental and Therapeutic Medicine
WoS Q Değeri
Q4
Scopus Q Değeri
Cilt
17
Sayı
1