Could Mean Platelet Volume Be Used as A Marker for Oral Aphthae and Activity of Behcet's Disease?

Basit Öğe Kaydı
dc.authorwosidVurgun, Eren/M-4918-2016
dc.contributor.authorDikker, Okan
dc.contributor.authorVardar, Muberra
dc.contributor.authorArabacı, Çiğdem
dc.contributor.authorUsta, Murat
dc.contributor.authorVurgun, Eren
dc.contributor.authorSoydan, Zekeriya
dc.date.accessioned2022-05-11T14:41:23Z
dc.date.available2022-05-11T14:41:23Z
dc.date.issued2016
dc.departmentFakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Fizyoloji Ana Bilim Dalı
dc.description.abstractObjective: Behcet's disease is a common inflammatory disease in our country. We aimed to determine whether mean platelet volume can be used as a marker for oral aphthae and the activity of Behcet's disease, Methods: Between 04/01/2010 and 30/07/2010, 78 patients from the Ok-meydani Training and Research Hospital Dermatology Clinic were retrospectively enrolled in this study, of which 15 patients had active Behcet's disease and 37 had inactive Behcet's disease that were diagnosed according to the International Criteria for Behcet's Disease; 26 control patients without any inflammatory disease were also evaluated, Mean platelet volume and laboratory indicators of inflammation were compared between the patients and control groups. Results: There were no significant differences in the mean platelet volume values between the active Behcet's disease group, inactive Behcet's disease group, and control group (p=0.678). Furthermore, there were no significant differences in the mean platelet volume values between patients with oral aphthae, patients without oral aphthae, and control patients (p=0.637). Conclusion: Our results demonstrate that mean platelet volume values cannot be used as a marker for oral aphthae and activity of Behcet's disease. However, immunosuppressive agents, such as colchicine and corticosteroids that are used in treating Behcet's disease, could affect the mean platelet volume values in active or inactive Behcet's disease by suppressing the inflammatory process. Therefore, we believe that the evaluation of the mean platelet volume values in large-scale studies that include patients with newly diagnosed Behcet's disease, which have not been treated, would be useful.
dc.identifier.doi10.5152/imj.2016.38981
dc.identifier.endpage13
dc.identifier.issn1304-8503
dc.identifier.issn2148-094X
dc.identifier.issue1en_US
dc.identifier.startpage9
dc.identifier.urihttps://doi.org/10.5152/imj.2016.38981
dc.identifier.urihttps://hdl.handle.net/20.500.11776/9166
dc.identifier.volume17
dc.identifier.wosWOS:000376296100003
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.institutionauthorSoydan, Zekeriya
dc.language.isotr
dc.publisherAves
dc.relation.ispartofIstanbul Medical Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectBehcet's disease
dc.subjectplatelet
dc.subjectinflammation
dc.subjectRheumatoid-Arthritis
dc.subjectPathophysiology
dc.subjectThrombopoiesis
dc.subjectLink
dc.titleCould Mean Platelet Volume Be Used as A Marker for Oral Aphthae and Activity of Behcet's Disease?
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
9166.pdf
Boyut:
77.38 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Tıp Fakültesi Koleksiyonu