Shifting Epidemiology of Hepatitis A Infection and Vaccination Status of Children Aged 6 Months-12 Years: Time for Mass Vaccination

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dc.authorid0000-0002-4060-0583
dc.authorid0000-0001-5992-9488
dc.authorid0000-0002-5630-3399
dc.authorwosidDonma, Mustafa Metin/ABF-2169-2021
dc.authorwosidDonma, Metin/AAB-6079-2020
dc.authorwosidNALBANTOGLU, BURCIN/A-5386-2018
dc.authorwosidDonma, Orkide/AAI-1853-2019
dc.contributor.authorNalbantoğlu, Burçin
dc.contributor.authorDonma, Mustafa Metin
dc.contributor.authorÖzdilek, Burcu
dc.contributor.authorKarasu, Erkut
dc.contributor.authorNalbantoğlu, Ayşin
dc.date.accessioned2022-05-11T14:37:13Z
dc.date.available2022-05-11T14:37:13Z
dc.date.issued2013
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı
dc.description.abstractObjective: This study was designed to determine the current age-related hepatitis A virus (HAV) seroprevalance, vaccination status of children and to evaluate the epidemiological shift in HAV serostatus living in Tekirdag, which is located in Thrace region, the European part of Turkey. Methods: Children 6 months-12 years of age with simple health problems were included. Blood samples were studied for HAV IgM and IgG collectively. A questionnaire addressing several characteristics of subjects was administered to obtain basic descriptive data on HAV epidemiology. Vaccination status of the children was recorded according to the immunization cards. Findings: The overall anti-HAV IgM and anti-HAV IgG prevalance in children aged 6 months-12 years was 3.3% and 25.4% respectively. Maximum hepatitis A IgM positivity was in the 7-12 years age group 4.8% (n=12; P<0.001) and maximum hepatitis A IgG positivity in the same age group was 34% (n=85; P<0.001). HAV vaccination rate among patients aged more than 2 years was 11.03%. HAV IgG seroprevalance was higher in children of low monthly income families (36.1%, n=78; P<0.001) than in the intermediate (17%, n=31) and high income families (11.1%, n=6). Conclusion: These results indicate a shift in Hepatitis A seroprevalance when compared with the previous studies. As HAV infection in childhood is decreasing, the pool of susceptible adolescents and young adults is increasing. Introduction of hepatitis A vaccination into the national immunization schedule of Turkey should be considered.
dc.identifier.endpage280
dc.identifier.issn2008-2142
dc.identifier.issn2008-2150
dc.identifier.issue3en_US
dc.identifier.pmid23795249
dc.identifier.startpage276
dc.identifier.urihttps://hdl.handle.net/20.500.11776/8621
dc.identifier.volume23
dc.identifier.wosWOS:000320853800004
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.institutionauthorNalbanto?lu, Burçin
dc.institutionauthorDonma, Mustafa Metin
dc.institutionauthorÖzdilek, Burcu
dc.institutionauthorKarasu, Erkut
dc.language.isoen
dc.publisherKowsar Corp
dc.relation.ispartofIranian Journal of Pediatrics
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectHepatitis
dc.subjectHepatitis A Virus
dc.subjectVaccination
dc.subjectImmunization
dc.subjectTurkey
dc.subjectSeroprevalence
dc.subjectIzmir
dc.subjectNeed
dc.subjectEra
dc.titleShifting Epidemiology of Hepatitis A Infection and Vaccination Status of Children Aged 6 Months-12 Years: Time for Mass Vaccination
dc.typeArticle

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