Evaluation of Interictal Electroencephalography Findings in Patients with Focal Epilepsy: Does Secondary Bilateral Synchrony Play a Role on Seizure Frequency?

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dc.authorwosidGündoğdu, Aslı Aksoy/C-3992-2016
dc.contributor.authorAltunan, Bengü
dc.contributor.authorGundogdu, Aslı Aksoy
dc.contributor.authorÜnal, Aysun
dc.date.accessioned2022-05-11T14:05:04Z
dc.date.available2022-05-11T14:05:04Z
dc.date.issued2020
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Nöroloji Ana Bilim Dalı
dc.description.abstractObjectives: Interictal electroencephalography (EEG) is an electrophysiological test used in daily practice and important in the diagnosis and treatment process for epileptic patients. Accurate assessment of the interictal epileptiform discharges (IEDs) and recognition of secondary bilateral synchrony (SBS) are important for the evaluation of appropriate treatment options. In this study, we investigated whether the presence of SBS is a risk factor for seizure frequency, treatment response, and localization. Methods: In this study, the data of 126 patients who were followed up with the diagnosis of epilepsy in the Neurology Outpatient Clinic of Namk Kemal University Education and Research Hospital were analyzed retrospectively. Demographic characteristics, seizure frequency, localization, treatment response and EEG characteristics of the patients were investigated and the results of 122 patients were obtained. Results: Fifty-eight (46%) of the patients were female, and 68 (54%) were male. The mean age was 36.5 +/- 16.4 (15-78) years. EEG of 15 patients (12.2%) was reported as SBS. Focal epileptiform abnormality was detected in 54 patients (44.2%) and focal irregular background activity (non-epileptic findings) was found in 12 patients (9.8%). When semiological features and EEG findings were evaluated together, 44 patients (34.9%) were classified as frontal lobe seizures, 66 patients (52.4%) as temporal lobe seizures, 16 patients (12.6%) as the others. Forty-six patients (36.5%) had no seizures, while 15 (11.9%) had one seizure per year, 46 (36.5%) had one seizure in one to six months, and 19 (15.1%) had daily or weekly seizures. Twenty-nine (23%) of the 46 seizure-free patients became seizure-free in an early stage, 17 patients (13.5%) became seizure-free after the sixth month of the treatment. Conclusion: Although the presence of IED and SBS in interictal EEG is not a risk factor for seizure frequency and treatment response, and the rate of SBS is higher in frontal lobe seizures. The presence of IED and SBS in the management of treatment may lead to false results.
dc.identifier.doi10.14744/epilepsi.2020.49140
dc.identifier.endpage192
dc.identifier.issn1300-7157
dc.identifier.issue3en_US
dc.identifier.startpage186
dc.identifier.urihttps://doi.org/10.14744/epilepsi.2020.49140
dc.identifier.urihttps://hdl.handle.net/20.500.11776/4885
dc.identifier.volume26
dc.identifier.wosWOS:000610799700007
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.institutionauthorAltunan, Bengü
dc.institutionauthorGundogdu, Aslı Aksoy
dc.institutionauthorÜnal, Aysun
dc.language.isotr
dc.publisherKare Publ
dc.relation.ispartofEpilepsi
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectInterictal EEG
dc.subjectseizure frequency
dc.subjectseizure localization
dc.subjectsecondary bilateral synchrony
dc.subjecttreatment response
dc.subjectDischarges
dc.subjectEeg
dc.titleEvaluation of Interictal Electroencephalography Findings in Patients with Focal Epilepsy: Does Secondary Bilateral Synchrony Play a Role on Seizure Frequency?
dc.typeArticle

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