Corpus callosum in schizophrenia with deficit and non-deficit syndrome: a statistical shape analysis

Basit Öğe Kaydı
dc.authorid0000-0001-6728-3664
dc.authorid0000-0001-9031-3040
dc.authorwosidTürk, Yaşar/N-5682-2018
dc.contributor.authorTürk, Yaşar
dc.contributor.authorErcan, İlker
dc.contributor.authorŞahin, İbrahim
dc.contributor.authorErdemli Gürsel, Başak
dc.contributor.authorUzunoğlu, Arda
dc.contributor.authorÖğe, Cem
dc.contributor.authorBeyazyüz, Elmas
dc.contributor.authorAlbayrak, Yakup
dc.date.accessioned2022-05-11T14:05:09Z
dc.date.available2022-05-11T14:05:09Z
dc.date.issued2021
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Ruh Sağlığı ve Hastalıkları Ana Bilim Dalı
dc.description.abstractBackground The corpus callosum (CC) is the most targeted region in the cerebrum that integrates cognitive data between homologous areas in the right and left hemispheres. Aims Our study used statistical analysis to determine whether there was a correlation between shape changes in the CC in patients with schizophrenia (SZ) (deficit syndrome (DS) and non-deficit syndrome (NDS)) and healthy control (HC) subjects. Methods This study consisted of 27 HC subjects and 50 schizophrenic patients (20 with DS and 30 with NDS). 3 patients with DS and 4 patients with NDS were excluded. Three-dimensional, sagittal, T1-spoiled, gradient-echo imaging was used. Standard anatomical landmarks were selected and marked on each image using specific software. Results As to comparing the Procrustes mean shapes of the CC, statistically significant differences were observed between HC and SZ (DS+NDS) (p=0.017, James's F-j=73.732), HC and DS (p<0.001, James's F-j=140.843), HC and NDS (p=0.006, James's F-j=89.178) and also DS and NDS (p<0.001, James's F-j=152.967). Shape variability in the form of CC was 0.131, 0.085, 0.082 and 0.086 in the HC, SZ (DS+NDS), DS and NDS groups, respectively. Conclusions This study reveals callosal shape variations in patients with SZ and their DS and NDS subgroups that take into account the CC's topographic distribution.
dc.identifier.doi10.1136/gpsych-2021-100635
dc.identifier.issn2096-5923
dc.identifier.issn2517-729X
dc.identifier.issue6en_US
dc.identifier.pmid34950854
dc.identifier.urihttps://doi.org/10.1136/gpsych-2021-100635
dc.identifier.urihttps://hdl.handle.net/20.500.11776/4908
dc.identifier.volume34
dc.identifier.wosWOS:000727733000001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.institutionauthorBeyazyüz, Elmas
dc.institutionauthorAlbayrak, Yakup
dc.language.isoen
dc.publisherBmj Publishing Group
dc.relation.ispartofGeneral Psychiatry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectschizophrenia
dc.subjectpsychiatry
dc.subjectneuropsychiatry
dc.subjectbiostatistics
dc.subjectWhite-Matter
dc.subjectMagnetic-Resonance
dc.subjectStructural Abnormalities
dc.subjectTemporal-Lobe
dc.subjectBrain
dc.subject1St-Episode
dc.subjectSymptoms
dc.subjectMemory
dc.titleCorpus callosum in schizophrenia with deficit and non-deficit syndrome: a statistical shape analysis
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
4908.pdf
Boyut:
3.45 MB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Tıp Fakültesi Koleksiyonu