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    Characteristics of our hypoxemic COVID-19 pneumonia patients receiving corticosteroids and mortality-associated factors
    (Taylor & Francis Ltd, 2022) Şengül, Aysun; Mutlu, Pınar; Özdemir, Özer; Satıcı, Celal; Turan, Muzaffer Onur; Arslan, Sertaç; Mirici, Arzu; Mutlu, Levent Cern; Fazlioglu, Nevin
    Background COVID-19 is a disease associated with diffuse lung injury that has no proven effective treatment yet. It is thought that glucocorticoids may reduce inflammation-mediated lung injury, disease progression, and mortality. We aimed to evaluate our patient's characteristics and treatment outcomes who received corticosteroids for COVID-19 pneumonia. Methods We conducted a multicenter retrospective study and reviewed 517 patients admitted due to COVID-19 pneumonia who were hypoxemic and administered steroids regarding demographic, laboratory, and radiological characteristics, treatment response, and mortality-associated factors. Results Of our 517 patients with COVID-19 pneumonia who were hypoxemic and received corticosteroids, the mortality rate was 24.4% (n = 126). The evaluation of mortality-associated factors revealed that age, comorbidities, a CURB-65 score of >= 2, higher SOFA scores, presence of MAS, high doses of steroids, type of steroids, COVID-19 treatment, stay in the intensive care unit, high levels of d-dimer, CRP, ferritin, and troponin, and renal dysfunction were associated with mortality. Conclusion Due to high starting and average steroid doses are more associated with mortality, high-dose steroid administration should be avoided. We believe that knowing the factors associated with mortality in these cases is essential for close follow-up. The use of CURB-65 and SOFA scores can predict prognosis in COVID-19 pneumonia.
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    Evaluation Of Vitamin B12 and D, Folic Acid and Homocystein Levels In Stable COPD Patients
    (European Respiratory Soc Journals Ltd, 2020) Turan, Muzaffer Onur; Sarıoğlu, Nurhan; Turan, Pakize Ayşe; Özdemir, Özer; Fazlıoğlu, Nevin; Köseoğlu, Mehmet; Mirici, Arzu
    [No Abstract Available]