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Öğe Absence of Middle Hepatic Vein Combined with Retro-Aortic Left Renal Vein: a Very Rare Case Report(Galenos Publ House, 2012) Turamanlar, Ozan; Kırpıko, Oğuz; Özen, Oğuz Aslan; Değirmenci, Bumin; Akçer, Sezer; Uygur, RamazanThe hepatic and renal veins drain into the inferior vena cava. The upper group of hepatic veins consists of three veins which extend to the posterior face of the liver to join the inferior cava. The left renal vein passes anterior to the aorta just below the origin of the superior mesenteric artery. We detected a variation in the hepatic and renal veins in a multislice CT angiogram of a nine-year-old male patient in the Radiology Department of Afyon Kocatepe University Medical School. The upper group hepatic veins normally drains into the inferior vena cava as three separate trunks, namely the right, left and middle. In our case, we found that only the right and left hepatic veins existed and the middle hepatic vein was absent. Furthermore, the left renal vein, which normally passes anterior to the abdominal aorta, was retro-aortic. Left renal vein variations are of great importance in planning retroperitoneal surgery and vascular interventions. Knowledge of a patient's hepatic vein and renovascular anatomy and determining their variations and anomalies are of critical importance to abdominal operations, transplantations and preoperative evaluation of endovascular interventions.Öğe Çoklu Patolojili meningoensefalosel olgusu(2013) Turamanlar, Ozan; Kırpıko, Oğuz; Özen, Oğuz Aslan; Sancaktar, MuratMeningoensefalosel, kalvaryumdaki bir defektten, kraniyal içeriklerin, kafatasının normal sınırlarının ötesine geçip çıkması olarak tanımlanabilir. Sağ maksiller bölgede şişlik şikayeti olan altı günlük bir erkek bebeğin çekilen kraniyal BT incelemesinde sağ temporal meningoensefalosele ait görünüm vardı. Ayrıca korpus kallosum disgenezisini dü- şündüren görünüm de bulunmaktaydı. Olgumuzdaki gibi bir anomali literatürde oldukça az rastlanan bir durumdur. Meningoensefalosel ile diğer konjenital beyin lezyonlarının birbirinden ayrımı, tedavi ve prognozlarının tamamen farklı olması nedeniyle büyük önem taşımaktadır.Öğe Modern anatominin kurucularından Hasan Mazhar Paşa(2012) Turamanlar, Ozan; Özen, Oğuz Aslan; Akçer, Sezer; Toktaş, MuhsinHasan Mazhar Paşa Türkiyede modern anatominin kurul- masında söz sahibi olan kişidir. O ve bir grup arkadaşı ile birlikte ülkemizde Türkçe tıp eğitimini başlattılar. Mazhar Paşa birçok tıp teriminin Türkçe karşılıklarını bulup yerleştirilmesinde, özellikle anatomi terimlerinin birçoğunun bulunup kullanılmasında önemli bir hizmet verdi. Aynı zamanda yüzlerce doktor yetiştirdi. Bunlar arasında Prof. Dr. F. Nafiz Uzluk ve Ord. Prof. Dr. Zeki Zeren de bulunmaktadır. Zeki Zeren Onun için Erdem ve fazilet sahibi 41 yıl öğretim üyeliği yapmış hocaların hocasıdır. der.Öğe Protective Effect of Alpha Lipoic Acid on Rat Sciatic Nerve Ischemia Reperfusion Damage(Galenos Publ House, 2015) Turamanlar, Ozan; Özen, Oğuz Aslan; Songur, Ahmet; Yağmurca, Murat; Akçer, Sezer; Mollaoğlu, Hakan; Aktaş, CevatBackground: Alpha lipoic acid is a potent antioxidant that plays numerous roles in human health. This study examined the effect of ALA on rat sciatic nerve ischemia reperfusion damage. Aims: Protective effect of alpha lipoic acid (ALA) on sciatic nerve following ischemia-reperfusion in rats was investigated by using light microscopy and biochemical methods. Provided that the protective effect of ALA on sciatic nerve is proven, we think the damage to the sciatic nerve that has already occurred or might occur in patients for various reasons maybe prevented or stopped by giving ALA in convenient doses. Study Design: Animal experiment. Methods: Forty-two adult male Sprague-Dawley rats (250-300 grams) were used in this study. Rats were randomly divided into six groups including one control (Group 1), one sham (Group 2), two ischemia-reperfusion (Groups 3 and 4) and two treatment groups (Groups5 and 6). Doses of 60 and 100 mg/kg ALA were given (Group 5 and 6) intra peritoneally twice, 1 and 24 hours before the ischemia to each treatment group. Ischemia was carried out the abdominal aorta starting from the distal part of the renal vein for two hours followed by reperfusion for three hours. In immunohistochemical methods, fibronectin immunoreactivity was analyzed. For biochemical analyses, the tissues were taken in eppendorf microtubes and superoxide dismutase (SOD) and glutathione peroxidase (GSHPx) enzyme activities as well as malondialdehyde (MDA) and nitricoxide (NO) levels were measured. Results: Fibronectin was observed to have increased significantly in the ischemia group; on the other hand, it was observed to have decreased in parallel to the doses in the ALA groups. Biochemical studies showed that SOD and GSHPx declined with ischemia-reperfusion, but the activities of these enzymes were increased in the treatment groups in parallel with the dose. It was found that increased MDA levels with ischemia-reperfusion were decreased in parallel with ALA dose. There were no statistically significant changes in NO. Conclusion: Increased fibronectin observed after ischemia/reperfusion of rat sciatic nerve is reduced after the administration of ALA. This indicates that the function of fibronectin, to reconnect cut nerve segments and regenerate nerves, is more prominent than its function in tissue healing after ischemia. ALA administered before ischemia decreases MDA and increases SOD and GSHPx. We think that ALA may protect against the pathological changes in ischemic nerve and may be used to devise more efficient treatments.Öğe Süperior Mezenterik Arter Kaynaklı Sağ Hepatik Arter ve Aksesuar Sol Renal Arter Olgusu(Namık Kemal Üniversitesi, Tıp Fakültesi, 2014) Turamanlar, Ozan; Gönül, Yücel; Kaçar, Emre; Çelik, Alaettin; Bal, AhmetNormalde truncus coeliacus’un üç dalından biri olan arteria hepatica communis, duedonum’un birinci kısmının üst yüzünde arteria hepatica propria ve arteria gastroduedonalis dallarını verir. Arteria renalis ise arteria mesenterica superior’un hemen aşağısında, aorta’nın yan taraflarından dik açı ile ayrılan iki adet kalın arterdir. Mide fundusu adeno karsinomu şüphesi ile takip edilen 64 yaşındaki erkek hastaya çekilen Spiral Bilgisayarlı Üst Abdominal BT’sinde a. hepatica dextra, varyasyonel olarak a. mesenterica superior’un proksimalinden, arteria hepatica sinistra ise truncus coeliacus’tan orjin almaktaydı. Olgumuzda çift arteria renalis sinistra varyasyonu da izlendi. Hem arteria renalis hem de arteria hepatica’lardaki varyasyonlar, giderek artan girişimsel radyolojik işlemler, transplantasyon ve vasküler cerrahi işlemler nedeniyle daha fazla önem kazanmaktadır. Bu yüzden hastamızdaki gibi mide karsinomu olup gastrektomi ve lenfadenektomi planlanan olgularda aorta abdominalis’ten ayrılan arterlerin anatomisi ve varyasyonlarının iyi bilinmesi gereklidir.Öğe Superior Sagittal Sinus Bifurcation Variation(Modestum Ltd, 2013) Özen, Oğuz Aslan; Turamanlar, Ozan; Kırpıko, Oğuz; Songur, Ahmet; Eser, OlcayIt is important to define the dural sinuses during assessment of the clinical presentations in neurosurgery and neurology and especially before performing surgical interventions involving the brain. Variations of dural sinuses are frequently seen in confluence of the sinuses. In our case, cranial venous MRI angiography of a 49-year-old male patient demonstrated that the superior sagittal sinus bifurcated near sutura lambdoidea of the cranium. These coursed as two separate branches and drained into the transverse sinus without forming the confluence of the sinuses. Sinus rectus joined to the left transverse sinus. We think that this unusual variation which was not reported before will contribute to the assessment of the neurologic presentations and also to the surgical interventions
