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    A single-center experience: Enteropathic arthritis in inflammatory bowel diseases
    (Elsevier, 2024) Cabuk, Baris; Gokten, Dilara Bulut; Solakoglu, Tevfik; Mete, Rafet; Kucukmetin, Nurten Turkel; Mercan, Ridvan
    Aim of the work: To ascertain the frequency of enteropathic arthritis among patients diagnosed with inflammatory bowel disease (IBD) and to investigate the relation between spondyloarthritis (SpA) and patients treated for IBD. Patients and methods: This study examined 124 adult patients with IBD. The evaluation encompassed both axial and peripheral SpA. Information pertaining to the patients ' age, gender, age at the time of IBD and SpA diagnosis, symptoms of inflammatory low back pain (iLBP), dactylitis, peripheral arthritis, history of uveitis, pelvic X-ray, sacroiliac joint magnetic resonance imaging (MRI), ankylosing spondylitis disease actviity score (ASDAS) and Bath ankylosing spondylitis disease actvity index (BASDAI) were compiled. Results: The IBD patients were 82 having ulcerative colitis (UC) and 42 Crohns disease (CD). 58 (46.8 %) were female and 66 (53.2 %) males. 36 (29 %) were diagnosed with SpA, 18 males and 18 females. The age of the patients was 49 +/- 11.2 years (18 -74 years). The duration of IBD was 5.96 +/- 5.54 years (1 -29 years). Sacroiliitis was assessed in 60 (48.3 %) patients using MRI. None of the patients had psoriasis or uveitis. Dactylitis was present in 1.6 % and enthesitis in 8 % of patients with IBD. In UC group, 18 (21.9 %) were diagnosed with SpA and in CD group, 18 (42.8 %) had SpA. No significant relationship was found between the diagnosis of UC/CD and the general SpA group. Conclusion: A considerable number of individuals with IBD also experience SpA. Any delay in diagnosing enteropathic arthritis could lead to functional limitations. Therefore, timely diagnosis is crucial to facilitate optimal treatment.
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    Acute peripancreatic fluid collection in acute pancreatitis: Incidence, outcome, and association with inflammatory markers
    (Wolters Kluwer Medknow Publications, 2023) Solakoglu, Tevfik; Kucukmetin, Nurten; Akar, Mustafa; Koseoglu, Hueseyin
    Background: The hospital outcomes and predictors of acute peripancreatic fluid collection (APFC) have not been well-characterized. In this study, we aimed to investigate the clinical outcomes of APFC in patients with acute pancreatitis (AP) and the role of the systemic immune-inflammation index (SII), systemic inflammation response index (SIRI), and C-reactive protein (CRP) level in predicting the occurrence of APFC. Methods: In this retrospective study, the complicated group (patients with APFC) and the uncomplicated group (patients without APFC) were compared for their clinical characteristics, hospital outcomes (mortality rate, intensive care unit admission rate, and length of hospital stay), pseudocyst formation, CRP levels, SII, and SIRI on admission and at 48 hours. Results: Of 132 patients with AP, 51 (38.6%) had APFC and eight (6.1%) had pancreatic pseudocysts. Of 51 patients with APFC, 15.7% had pancreatic pseudocysts. Pseudocyst did not develop in the uncomplicated group. SII value at 48 h [median 859 (541-1740) x 109/L vs. 610 (343-1259) x 109/L, P = 0.01] and CRP level at 48 h [89 (40-237) mg/L vs. 38 (12-122) mg/L, P = 0.01] were higher in the complicated group than in the uncomplicated group. The length of hospital stay was longer in the complicated group, compared with the uncomplicated group [median 8 days (5-15), vs. 4 days (3-7), P < 0.001, respectively]. No significant difference was detected between the two study groups' mortality rates and intensive care unit admission rates. Conclusions: While 38.6% of the AP patients had APFC, 6.1% of all patients and 15.7% of the patients with APFC had pancreatic pseudocysts. APFC was found to lengthen the hospital stay and to be associated with the SII value and CRP level measured at 48 h.