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Öğe Clinicopathological Evaluation of Cervical Polyps(Aves, 2011) Yüksel, Mehmet Aytaç; Çelik, Serdar; Abalı, Remzi; Temel, İlkbal; Boran, Ahmet Birtan; Purisa, SevimObjectives: The aim of this study was to evaluate the clinicopathologic and demographic features in patients with cervical polyps. Methods: We performed a search of the database to retrieve all cases with a cervical polyp who were treated in the Obstetrics and Gynecology Department of Istanbul Education and Research Hospital between January 2006 and December 2010. The patients' symptoms and the size and histopathologic diagnosis of the polyp were reviewed. Patients were divided into four age groups as: Group I: <30, Group II: 30-44, Group III: 45-55, and Group IV: >55 years. Results: The mean age was 50.36 +/- 9.36 years. The mean polyp size was 12.46 +/- 8.31 mm and the recurrence rate was 1.8% (7/381). The majority of cervical polyps were asymptomatic (66.1%). Furthermore, there was no primary malignancy on the cervical polyps. There were no significant differences in terms of diameter, symptoms, rate of recurrence, and histopathologic findings between the four groups (p>0.05). Conclusion: Cervical polyps are benign lesions. Many of them are asymptomatic and are found at the time of routine gynecologic examination. Routine removal of polyps is reasonable and easy; pathological evaluation is needed to rule out other possibilities.Öğe Evaluation of CA 19-9 levels in ovarian dermoid cysts(2011) Yüksel, Mehmet Aytaç; Abalı, Remzi; Aras, Özlem; Temel, İlkbal; Ünal, Fehmi; Boran, Ahmet Birtan; Purisa, SevimObjective: We aimed to evaluate the CA 19-9 levels in ovarian dermoid cysts. Material and Methods: Tumor markers and clinicopathologic features of 114 patients, treated between 2006-2010 in Department of Obstetrics and Gynecology, Istanbul Education and Research Hospital were evaluated retrospectively. All patients pathology reports revealed mature cystic teratoma. Patients evaluated according to the CA 19-9 levels (group1: normal, group2: high). Age, tumors size, bilaterality and CA19-9 levels were studied. Results: Mean age of the patients was 40.7 ± 12.3 (20-75). Nine patients (%12.5) were at postmenopausal ages. Tumor diameters were between 2-25 cm. Mean serum CA 19-9 level was 39.2 ± 76.8 U/mL, mean serum CA 125 level was 23.8 ± 29.1 U/ml, mean serum AFP level was 1.8 ± 1.5 ng/mL, mean serum CEA level was 1.7 ± 1.5 ng/mL and mean serum CA 15-3 was 15.3 ± 6.7 U/mL. CA 19-9 levels were the highest marker among patients (%19.4). Differences in mean age, tumor diameters and tumor marker levels excluded CA 19-9, were not statistically significant between two groups. Conclusion: Ca19-9 is the most frequent tumor marker detected high in mature cystic teratoma patients. Yet it is not sufficient alone for diagnosis. Tumor size and bilaterality is not correlated to the tumor marker levels. Copyright © 2011 by Türkiye Klinikleri.Öğe Servikal poliplerin klinik-patolojik değerlendirilmesi(2011) Yüksel, Mehmet Aytaç; Çelik, Serdar; Abalı, Remzi; Temel, İlkbal; Boran, Ahmet Birtan; Purisa, SevimAmaç: Servikal polipli hastaların klinikopatolojik ve demografik özellikleri incelendi. Gereç ve Yöntem: İstanbul Eğitim ve Araştırma Hastanesi, Kadın Hastalıkları ve Doğum Kliniği’nde Ocak 2006 ile Aralık 2010 yılları arasında servikal polip nedeniyle tedavi edilen 381 hastanın verileri geriye dönük olarak incelendi. Hastalar yaşlarına göre dört gruba ayrıldı; Grup I: < 30, Grup II: 30-44, Grup III: 45-55, Grup IV: >55. Hastaların, polip çapları, semptomları ve histopatolojik tanıları karşılaştırıldı. Bulgular: Hastaların ortalama yaşı 50,36±9,36 idi. Poliplerin ortalama çapı; 12,46±8,31 mm idi. Nüks oranı %1,8 (7/381) idi. Poliplerin büyük çoğunluğu asemptomatikdi (%66,1). Servikal poliplerde primer malignensi saptanmadı. Dört grup arasında çap, semptom, nüks oranı ve histopatolojik tanı açısından istatistiki bir fark yoktu (p>0,05). Sonuç: Servikal polipler iyi huylu lezyonlardır. Çoğu servikal polipler asemptomatik olup rutin jinekolojik muayene sırasında tespit edilirler. Çıkarılmalarının kolay olması, diğer patolojileri ekarte etmek için patolojik değerlendirme gerekliliğinden dolayı rutin çıkarılması mantıklı olabilir.