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Öğe Leukocytoclastic vasculitis due to duloxetine(John Libbey Eurotext Ltd, 2015) Erfan, Gamze; Alp, Recep; Albayrak, Şule; Oğuz, Keriman; Kalayci, Serkan; Öznur, Meltem; Kulaç, Mustafa[No Abstract Available]Öğe Permanent Neurological Damage Due To Trauma: An Important Conclusion in Forensic Medicine(Journal Neurological Sciences, 2013) Kumral, Bahadır; Ünal, Aysun; Oğuz, Keriman; Gündoğmuş, Ümit NaciPurpose: It is aimed to evaluate the demographic, etiological and clinical findings of the victims who were sent to Council of Forensic Medicine by the court of law and prosecutor's office and in whom permanent neurological disorders was diagnosed. Method: Case files belonged to victims were examined retrospectively, whether they had permanent neurological damage or not was asked to Council of Forensic Medicine 2nd Expertise Chamber between the years of 2005 and 2009. Demographic characteristics, trauma types, neurological examination and radiological imaging findings, other examinations that were done, treatment they have been receiving and their disability levels have been thoroughly evaluated. Findings: As a result of examination conducted at Council of Forensic Medicine, head trauma and medulla spinalis were the major causes for permanent neurological disorders. Cognitive Function Disorder and Epilepsy were the diagnoses which caused permanent neurological damage the most often. Ranking 3 and up in 89 victims, ranking 3 and down in 64 victims were assessed. Conclusion: The most important two cause of trauma are traumatic brain and spinal cord damage, the most important neurological symptoms are cognitive function disorder and seizure in the victims who were sent to Council of Forensic Medicine for presence of permanent neurological disorders to be determined.Öğe Possible association between vitamin D deficiency and restless legs syndrome(Dove Medical Press Ltd, 2014) Oran, Mustafa; Ünsal, Cüneyt; Albayrak, Yakup; Tülübaş, Feti; Oğuz, Keriman; Avcı, Okan; Gürel, AhmetBackground and aim: Restless legs syndrome (RLS) is a distressing sleep disorder that occurs worldwide. Although there have been recent developments in understanding the -pathophysiology of RLS, the exact mechanism of the disease has not been well elucidated. An increased prevalence of neurologic and psychiatric diseases involving dopaminergic dysfunction in vitamin D-deficient patients led us to hypothesize that vitamin D deficiency might result in dopaminergic dysfunction and consequently, the development of RLS (in which dopaminergic dysfunction plays a pivotal role). Thus, the aim of this study was to evaluate the relationship between vitamin D deficiency and RLS. Methods: One hundred and fifty-five consecutive patients, 18-65 years of age, who were admitted to the Department of Internal Medicine with musculoskeletal symptoms and who subsequently underwent neurological and electromyography (EMG) examination by the same senior neurologist, were included in this study. The patients were divided into two groups according to serum 25-hydroxyvitamin D (25(OH) D) (a vitamin D metabolite used as a measure of vitamin D status) level: 36 patients with serum 25(OH) D levels. 20 ng/mL comprised the normal vitamin D group, and 119 patients with serum 25(OH) D levels >= 20 ng/mL comprised the vitamin D deficiency group. The two groups were compared for the presence of RLS and associated factors. Results: The two groups were similar in terms of mean age, sex, mean body mass index (BMI), and serum levels of calcium, phosphate, alkaline phosphatase (ALP), and ferritin. The presence of RLS was significantly higher in the vitamin D deficiency group (chi(2)=12.87, P<0.001). Regression analysis showed vitamin D deficiency and serum 25(OH) D level to be significantly associated with the presence of RLS (odds ratio [OR] 5.085, P<0.001 and OR 1.047, P=0.006, respectively). Conclusion: The present study demonstrated a possible association between vitamin D -deficiency and RLS. Given the dopaminergic effects of vitamin D, 25(OH) D depletion may lead to dopaminergic dysfunction and may have a place in the etiology of RLS. Prospective vitamin D treatment studies are needed to confirm this relationship and to evaluate the efficacy of vitamin D as a treatment for RLS patients.Öğe The value of rehabilitation of camptocormia(Geriatrics Society, 2014) Yıldırım Güzelant, Aliye; Sarıfakıoğlu, Ayşe Banu; Oğuz, Keriman; Ünal, AysunParkinson's disease is a neurodegenerative disorder characterized by progressive loss of muscle control, stiffness, slowness, and impaired balance. In the later stages, posture disorders can be seen. In this study we aimed to present the successful results of rehabilitation therapy in three patients with Parkinson's disease and camptocormia. A patient-centered rehabilitation program was started. We aimed to improve functional capacity, balance, coordination and postural control. Home exercise programs were prepared to enhance patients' daily living activities. After a six-week rehabilitation program, significant improvement was observed on the Schwab-England Activities of Daily Living Scale and patients could walk on flat ground while maintaining erect posture for at least 50 meters with one-side support. On the second month of follow-up, the clinical improvement continued. These cases showed that effective exercise therapy and patient education may improve the quality of life and functionality in Parkinson's disease and therefore rehabilitation should be part of treatment at all stages of the disease.Öğe Travmaya Bağlı Kalıcı Nörolojik Hasar: Adli Tıpta Önemli Bir Son Karar(2013) Kumral, Bahadır; Ünal, Aysun; Oğuz, Keriman; Gündoğmuş, Ümit NaciAmaç: Travma sonrası mağdurda ortaya çıkan yaralanmanın şiddetinin belirlenmesi, sanığa ceza verilip verilmeyeceği, verilecek ise ceza artırımına gidilip gidilmeyeceği konusunda önemli rol oynar. Bu çalışmada Adli Tıp Kurumuna Mahkemeler ve Savcılıklar tarafından gönderilen ve muayenesi sonucunda kalıcı nörolojik hasar tespit edilen olguların demografik, etiyolojik ve klinik bulgularının değerlendirilmesi amaçlanmıştır. Yöntem: Adli Tıp Kurumu İkinci İhtisas Kuruluna 2005-2009 yılları arasında kalıcı nörolojik hasarı olup olmadığı sorulan olgulara ait dosyalar retrospektif olarak incelendi. Olguların demografik özellikleri, travma türleri, nörolojik muayene ve radyolojik görüntüleme bulguları, yapılmış olan diğer tetkikleri, almakta oldukları tedaviler ve özürlülük dereceleri (Rankin) ayrıntılı olarak değerlendirildi. Bulgular: Adli Tıp Kurumundaki olguların muayeneleri sonucunda kalıcı nörolojik hasara en sık kafa travması ve medulla spinalis yaralanması neden olmuştu. Bilişsel işlev bozuklukları ve epilepsi en sık kalıcı nörolojik hasara neden olan nörolojik tanılardı. Kalıcı nörolojik hasara yol açan travmatik olaylar türleri açısından incelendiğinde, 70 olguda trafik kazası, 27 olguda künt travmatik yaralanma, 27 olguda ateşli silah yaralanması, 13 olguda delici kesici alet yaralanması, 14 olguda yüksekten düşme, bir olguda yanık, bir olguda suda boğulma neden olarak saptandı. Rankin 89 olguda üç ve üçün üzerinde, 64 olguda üçün altında olarak değerlendirildi. Sonuç: Adli Tıp Kurumunda kalıcı nörolojik hasar varlığının değerlendirilmesi amacı ile gönderilen olgularda en önemli iki sebep travmatik beyin ve spinal kord hasarı, en önemli iki nörolojik belirti bilişsel işlev bozukluğu ve nöbettir. Beyin Cerrahisi ve Nöroloji uzmanlarının travmanın erken döneminden itibaren yaptıkları nörolojik muayeneye ait bulguların ayrıntılı kayıt edilmesi adli yargılama sürecinde daha hızlı ve sağlıklı görüş bildirilmesine, maddi manevi hak kayıplarının önlenmesine yardımcı olacaktır.
