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    Effect of a Single Dose of Deflazacort on Postoperative Pain, Swelling, and Trismus after Impacted Lower Third Molar Surgery: Randomised Clinical Trial
    (Mdpi, 2024) Kaplan, Volkan; Cigerim, Levent; Feslihan, Erkan; Cigerim, Saadet Cinarsoy
    Background and Objectives: The aim of this study was to investigate the efficacy of a single preoperative dose of deflazacort on pain, swelling, and trismus after impacted lower third molar surgery. Materials and Methods: This randomised, prospective, double-blind, split-mouth clinical study included 26 healthy individuals with bilaterally impacted lower third molars. Group 1 was given a placebo (single-dose vitamin C tablet), and group 2 was given a single 30 mg dose of deflazacort 1 h prior to surgery. Pain was evaluated using the visual analogue scale for 1 week postoperatively. Oedema (in mm) and trismus (in mm) were evaluated preoperatively and on postoperative days 2 and 7. The Mann-Whitney U test was applied for group analyses. p values < 0.05 were considered statistically significant. Results: Postoperative pain scores were significantly lower in the deflazacort group at the 6th and 12th hours after surgery (p < 0.05). There were no significant differences in trismus between the groups at any time point (p > 0.05). There was less oedema in the deflazacort group on postoperative days 2 and 7, without any statistically significant difference (p > 0.05). Conclusions: A single preoperative dose of 30 mg deflazacort was found to be clinically effective in reducing pain and oedema after extraction of impacted lower third molars.
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    Evaluation of dental anxiety in patients undergoing second-stage surgery with er, cr: YSGG laser treatment: Randomized clinical trial
    (Yuzuncu Yil Universitesi Tip Fakultesi, 2020) Tunç, Serap Keskin; Alpaslan Yaylı, Nazlı Zeynep; Talmaç, Ahmet Cemil; Feslihan, Erkan; Kaplan, Volkan
    Oral surgical procedures cause high-pain expectation and consequent anxiety in patients. The aim of this study is to compare the effects of Er, Cr: YSGG laser and scalpel method on dental anxiety level during second-stage implant surgery. 96 patients with 304 osseointegrated implants were divided into two groups. Implants embedded under the oral mucosa were exposed with scalpel or laser surgery. Before the operation the patients were asked to fill the STAI and DAS while resting in the waiting room. In addition, postoperative daily analgesic use, VAS scores perioperativly and on the postoperative 1st, 2nd and 3rd days and demographic information such as age and gender were also recorded. There was no statistically significant relationship between surgical method and anxiety levels (p>0.05. Also, the differences between the scalpel and laser groups in terms of total DAS and STAI scores were statistically insignificant (p>0.05). But statistically significant difference was found between surgical method and the analgesic consumption (p<0.05). A higher rate of analgesic consumption was observed in the scalpel group. The use of Er,Cr;YSGG laser could reduce pain during minor oral surgical procedures but had no significant effect on dental anxiety. Different modalities that could provide additional benefits in overcoming this situation should be investigated. © 2020, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
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    Evaluation of the efficacy of topical rifamycin application on postoperative complications after lower impacted wisdom teeth surgery
    (Elsevier, 2024) Cigerim, Levent; Orhan, Zeynep Dilan; Kaplan, Volkan; Cigerim, Saadet Cinarsoy; Feslihan, Erkan
    Purpose: This study aimed to evaluate the efficacy of a single-dose topical rifamycin application on postoperative complications after impacted lower third molar surgery. Materials and methods: This prospective, controlled clinical study consisted of individuals with bilaterally impacted lower third molars that would be extracted for orthodontic reasons. The extraction sockets were irrigated with 3 ml/250 mg of rifamycin solution in Group 1, while in Group 2 (control group) the extraction sockets were irrigated with 20 ml of physiological saline. Pain intensity was measured daily for 7 days by using visual analog scale. Trismus and edema were evaluated preoperatively and on the postoperative days 2 and 7 by calculating the proportional changes in maximum mouth opening and mean distance between reference points of the face, respectively. Paired samples t-test, Wilcoxon signed rank test and Chi-square test were used to analyze the study variables. Results: 35 patients (19 female, 16 male) were included in the study. The mean age of all participants was 22.19 4.98. Alveolitis was observed in 8 patients, (6 in the control group, 2 in the rifamycin group). There was no statistically significant difference between groups in terms of trismus and swelling measurements on the 2nd and 7th postoperative days (p>0.05). VAS scores were significantly low in rifamycin group on postoperative days 1 and 4 (p<0.05). Conclusion: Within the limits of the present study, topical rifamycin application reduced the incidence of alveolitis, prevented infection, and provided analgesic effect after surgical removal of impacted third molars. (c) 2023 Elsevier Masson SAS. All rights reserved.
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    Treatment of aphthous ulcers with photodynamic therapy: A randomized controlled clinical study
    (Elsevier, 2024) Eroglu, Cennet Neslihan; Feslihan, Erkan; Karaca, Busra; Elasan, Sadi
    Background: This study aims to assess whether photodynamic therapy (PDT) offers a clinically effective alternative for treating oral aphthous ulcers, contributing to the ongoing quest for methods to expedite their treatment process amidst the limited understanding of their etiology. Materials and Method: The study involved thirty volunteers with aphthous ulcers, split equally between a control group and a PDT group. Patients in the PDT group received laser treatment using Indocyanine green upon admission, while the control group received no intervention. Lesion diameter was measured at presentation and on the 3rd, 5th, and 7th days for all patients, with wound healing assessed on the 7th day. Additionally, pain levels were evaluated using the Visual Analog Scale (VAS) preoperatively and on the 1st, 3rd, 5th, and 7th days for the PDT group, and on the corresponding days for the control group. Results: Lesion diameters in the PDT group showed a significant reduction over time (p p = 0.001), particularly from preoperative to final measurements. The control group also exhibited a decrease, albeit slower (p = 0.001). The 7th-day healing scores favored the PDT group significantly (p p = 0.012). VAS scores in the PDT group decreased significantly over time (p p = 0.001), indicating pain reduction. A similar trend was observed in the control group, albeit slower. Between-group differences in healing data and pain data were statistically significant. Conclusion: PDT proves effective in reducing aphthous ulcer diameters and pain intensity, facilitating faster healing than the control group. These results advocate for PDT as a viable treatment option for aphthous lesions.