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  • Küçük Resim
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    Superior Sagittal Sinus Bifurcation Variation
    (Modestum Ltd, 2013) Özen, Oğuz Aslan; Turamanlar, Ozan; Kırpıko, Oğuz; Songur, Ahmet; Eser, Olcay
    It is important to define the dural sinuses during assessment of the clinical presentations in neurosurgery and neurology and especially before performing surgical interventions involving the brain. Variations of dural sinuses are frequently seen in confluence of the sinuses. In our case, cranial venous MRI angiography of a 49-year-old male patient demonstrated that the superior sagittal sinus bifurcated near sutura lambdoidea of the cranium. These coursed as two separate branches and drained into the transverse sinus without forming the confluence of the sinuses. Sinus rectus joined to the left transverse sinus. We think that this unusual variation which was not reported before will contribute to the assessment of the neurologic presentations and also to the surgical interventions
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    The Effect of Electromagnetic Radiation on the Rat Brain: An Experimental Study
    (Turkish Neurosurgical Soc, 2013) Eser, Olcay; Songur, Ahmet; Aktaş, Cevat; Karavelioğlu, Ergun; Çağlar, Veli; Aylak, Firdevs; Kanter, Mehmet
    AIM: The aim of this study is to determine the structural changes of electromagnetic waves in the frontal cortex, brain stem and cerebellum. MATERIAL and METHODS: 24 Wistar Albino adult male rats were randomly divided into four groups: group I consisted of control rats, and groups II-IV comprised electromagnetically irradiated (EMR) with 900, 1800 and 2450 MHz. The heads of the rats were exposed to 900, 1800 and 2450 MHz microwaves irradiation for 1h per day for 2 months. RESULTS: While the histopathological changes in the frontal cortex and brain stem were normal in the control group, there were severe degenerative changes, shrunken cytoplasm and extensively dark pyknotic nuclei in the EMR groups. Biochemical analysis demonstrated that the Total Antioxidative Capacity level was significantly decreased in the EMR groups and also Total Oxidative Capacity and Oxidative Stress Index levels were significantly increased in the frontal cortex, brain stem and cerebellum. IL-1 beta level was significantly increased in the EMR groups in the brain stem. CONCLUSION: EMR causes to structural changes in the frontal cortex, brain stem and cerebellum and impair the oxidative stress and inflammatory cytokine system. This deterioration can cause to disease including loss of these areas function and cancer development.
  • Küçük Resim
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    The protective effect of avocado soybean unsaponifilables on brain ischemia/reperfusion injury in rat prefrontal cortex
    (Taylor & Francis Ltd, 2011) Eser, Olcay; Songur, Ahmet; Yaman, Mehmet; Coşar, Murat; Fidan, Hüseyin; Şahin, Onder; Büyükbaş, Sadık
    Object. We investigated the protective effects of avocado/soybean unsaponifiables (ASU) on the prefrontal cortex (PFC) after global brain ischemia/reperfusion (I/R) injury in rats. Methods. Rats were randomly divided into three experimental groups as follows: Group I was control rats, Group II was ischemia rats, Group III was Isch+ASU rats. Brain ischemia was produced via four-vessel occlusion model. These processes followed by reperfusion for 30 min for both II and III groups. Rats were sacrificed and their brains were removed immediately. Malondialdehyde (MDA) and superoxide dismutase (SOD) were measured in left PFC, levels of TNF-alpha concentration were measured in the plasma. The number of apoptotic neurons was assayed in histological samples of the right PFC. Results. MDA and TNF-alpha levels as well as the number of apoptotic neurons were observed to have decreased significantly in Group III compared to Group II, while SOD activities have been found to have increased significantly in Group III in comparison to Group II, significantly. Conclusions. We think that ASU might have an antioxidant and neuroprotective effects in brain I/R injured rats.
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    Volumetric analysis of vertebral hemangiomas: A retrospective study
    (2013) Songur, Ahmet; Eser, Olcay; Alkoç, Ozan Alper; Toktaş, Muhsin; Çağlar, Veli; Kaner, Tuncay; Karavelioğlu, Ergün
    Amaç: Bu çalışmanın amacı, bel ağrısı olan hastaların MRG görüntülerinde T12-L5 seviyelerinde vertebral hemanjiomların lokalizasyonunu ve hacmini analize etmektir. Metod: 150 hastanın torako-lomber MR görüntüleri geriye dönük olarak incelendi. Sagital vertebra görüntülerinde vertebra korpusunda hemanjiom tespit edilenler incelendi ve cinsiyet, vertebra ve vertebra korpus lokalizasyonuna göre bulgular değerlendirildi. Volümetrik değerlendirme sagittal planda gerçekleştirildi ve Cavalieri prensiplerine göre hesaplandı. Sonuçlar: 22si kadın olmak üzere toplam 24 hastada hemanjiom tespit edildi. İki hastanın değişik vertebra korpusunda iki adet hemanjiomu mevcuttu. Hemanjiomların T12-L5 vertebra korpuslarında lokalizasyonu sırasıyla: 6 (% 23,08), 6 (% 23,08), 3 (% 11,54), 6 (% 23,08), 3 (% 11,54), ve 2 (% 7,69) idi. Sadece 1 (% 3,84) hemanjiom orta bölümdeydi. Kalanların 7 (% 26,92)si ve 18 (% 69,23)i sırasıyla ön ve arka yarıdaydı. Vertebral hemanjiomların ortalama hacimleri T12-L5 vertebra seviyelerinde sırasıyla 0.780±0.165, 1.018 ± 0.210, 0.527 ± 0.079, 2.282 ± 1.333, 3.417 ± 1.598, 0.910 ± 0.070 cm3 dü. Vertebral hemanjiomların total ortalama hacmi ise 1.484 ± 0.393cm3 bulundu. Sonuç: Vertebral hemanjiomların radyolojik özelliklerinde belirli hacimsel farklılık vardır. Bu çalışma, klinik semptomları ve hasta özgeçmişini daha iyi anlamak için hemanjiomların lokalizasyonu, özellikleri ve hacminin önemini belirtmektedir.