Yazar "Engin, Mesut" seçeneğine göre listele

Listeleniyor 1 - 7 / 7
  • Küçük Resim Yok
    Öğe
    Could the echocardiographic parameters be a predictor to estimate cerebrovascular events in patients with micro-atrial fibrillation?
    (2023) Aydın, Cihan; Engin, Mesut
    Objectives: This study examined possible predictors of stroke [left atrial sphericity index (LASI), left atrial kinetic energy (LAKE), left atrial volume index (LAVI) atrial electromechanical delay (AEMD)] intervals in patients with micro-atrial fibrillation (micro-AF). Patients and methods: A total of 102 consecutive patients (40 males, 62 females; mean age: 61.5±9.2 years; range, 18 to 75 years) diagnosed with micro-AF on rhythm Holter were included in this retrospective study between June 2021 and October 2021. Cranial magnetic resonance and computed tomography images of these patients were scanned from the hospital database. The patients were divided into two groups according to their stroke status (Group 1, the stroke group [n=25]; Group 2, the nonstroke group [n=77]). The LASI was calculated as a fraction of the left atrial maximum volume to the left atrial volume of the sphere in a four-chamber view. The biplane method of disks was used to calculate left atrium volume. The LAVI was calculated by dividing left atrium (LA) volume by the body surface area of patients. Atrial electromechanical delay intervals were calculated from the atrial walls by tissue Doppler imaging. These two groups were compared to assess whether echocardiographic parameters could be a predictor of cerebrovascular events. Results: There was a statistically significant difference between Groups 1 and 2 in terms of left (75.7±4.5 vs. 68.4±3.5, p<0.001) and right (69.5±7.1 vs. 57±3.2, p<0.001) atrial lateral wall and LA medial wall (72±4 vs. 66.2±3.5, p<0.001) electromechanical delay times, LAVI (38.9±3.3 vs. 30.9±3.8, p<0.001), LASI (0.78±0.05 vs. 0.67±0.4, p<0.001), and LAKE (3.7±0.9 vs. 7.9±1.9, p<0.001), left atrial diameter (40±5 vs. 38±2, p<0.001). Conclusion: Changes in LASI, LAVI, LAKE, left atrial diameter, and atrial AEMD times may be a predictor of stroke in patients with micro-AF.
  • Küçük Resim
    Öğe
    Ebstein's anomaly associated with biventricular noncompaction
    (Springer Japan Kk, 2021) Aydın, Cihan; Engin, Mesut
    [No Abstract Available]
  • Küçük Resim
    Öğe
    Is there a difference between normotensive and hypertensive patients in terms of blood parameters and cardiovascular diseases?
    (2021) Aydın, Cihan; Alpsoy, Şeref; Engin, Mesut; Yavuz, Şenol
    Objectives: It has been stated in various studies that there is a difference in some blood parameters between hypertensive and normotensive patients for a long time. Mean platelet volume (MPV), and red blood cell distribution width (RDW), have been studied in hypertensive patient groups in many studies. Hypertension is a classic risk factor for ischemic stroke and myocardial ischemia, as known. In our study, we examined whether there was a difference between hypertensive patient groups and normotensive patients in terms of blood parameters such as MPV and RDW, and the incidence of stroke and myocardial infarction.Methods: Blood samples and twenty-four-hour ambulatory blood pressure monitoring (ABPM) results of 552 patients admitted to our outpatient clinic with a pre-diagnosis of hypertension were retrospectively analyzed. According to ABPM results, we divided the study participants into four groups; dippers, non-dippers, extreme dippers, and normotansives. Complete blood count and biochemical test results were found in the database of our hospital for all patients and differences between groups were investigated.Results: One hundred seventy three normotensives (Group 1) (mean age, 47.4 ± 15.4 years), 210 non-dippers (Group 2) (mean age, 53.8 ± 15.8 years), 67 extreme dippers (Group 3) (mean age, 49.1 ± 15.9 years) and 102 dippers (Group 4) (mean age, 52.2 ± 12.5 years). Daytime mean systolic blood pressure (SBP) and diastolic blood pressure (DBP) and night-time mean SBP and DBP were significantly different in groups (Group 1: 117 [90-193] mmHg and 71 [55-87] mmHg; Group 2: 137 [107-188] mmHg and 83 [107-188] mmHg; Group 3: 143 [115-193] mmHg and 88 [56-122] mmHg; and Group 4: 140.5 [116-173] mmHg and 76 [55-124] mmHg), p < 0.001; respectively. MPV and RDW levels were different in all four groups (p < 0.001). We found a significant difference in the rates of stroke and coronary artery disease between the four groups (p = 0.018 and p = 0.002, respectively). In the ROC curve analysis MPV had sensitivity of %77. 8 and specificity of 78. 1% for stroke when the cut-off value MPV was 9.25 (Area under curve: 0.808, 95% confidence interval: 0.726-0.889, p < 0.001).Conclusions: In our study, MPV and RDW levels and the rates of stroke and cardiovascular disease were significantly higher in non-dipper patients compared to other groups.
  • Küçük Resim Yok
    Öğe
    Letter: Inflammatory Markers and Coronary Collateral Circulation
    (Sage Publications Inc, 2024) Demirkiran, Aykut; Aydin, Cihan; Engin, Mesut
    [Abstract Not Available]
  • Küçük Resim
    Öğe
    Pediatricians' COVID-19 experiences and views on the willingness to receive COVID-19 vaccines: a cross-sectional survey in Turkey
    (Taylor & Francis Inc, 2021) Gonullu, Erdem; Soysal, Ahmet; Atici, Serkan; Engin, Mesut; Yesilbas, Osman; Kasap, Tuba; Karabayir, Nalan; Yıldız, İsmail
    Developing an effective and safe vaccine against Covid-19 will facilitate return to normal. Due to hesitation toward the vaccine, it is crucial to explore the acceptability of the COVID-19 vaccine to the public and healthcare workers. In this cross-sectional survey, we invited 2251 pediatricians and 506 (22%) of them responded survey and 424 (84%) gave either nasopharyngeal swap or antibody assay for COVID-19 and 71 (14%) of them got diagnosis of COVID-19. If the effective and safe COVID-19 vaccine was launched on market, 420 (83%) of pediatrician accepted to get vaccine shot, 422 (83%) of them recommended vaccination to their family members, 380 (75%) of them accepted to vaccine their children and 445 (85%) of them offered vaccination to their pediatric patients. Among the participated pediatricians 304 (60%) of them thought COVID-19 vaccine should be mandatory. We found that there are high COVID-19 vaccine willingness rates for pediatricians for themselves, their own children, family members and their pediatric patients. We also found that being a pediatric subspecialist, believing in achieving an effective vaccine, willingness to participate in the phase 1-2 clinical vaccine trial, willingness to get an influenza shot this season, believing a vaccine and vaccine passport should be mandatory were significant factors in accepting the vaccine. It is important to share all information about COVID-19 vaccines, especially effectiveness and safety, with the public in a clear communication and transparency. The opposite will contribute to vaccine hesitancy and anti-vaccine movement.
  • Küçük Resim
    Öğe
    Predictive Values of Inflammation Indexes in Predicting Mortality in Patients with COVID 19 Hospitalized in General Intensive Care Unit
    (2022) Engin, Mesut; Yıldırım, İlker; Arar, Makbule Cavidan; Amaç, Bişar; Alpsoy, Şeref; Aydın, Cihan; Gültekin, Ahmet
    Objective: Causing a global pandemic, the coronavirus disease 2019 (COVID-19) has caused millions of people to become infected and many more to die. In this study we aimed to investigate whether routinely evaluated clinical and laboratory values ??can predict the mortality of patients with COVID-19 disease.Materials and Methods: In our study, routine laboratory parameters of 89 patients hospitalized in the general intensive care unit with the diagnosis of COVID 19 were retrospectively analyzed. The aggregate index of systemic inflammation (AISI) and other inflamatuar values were calculated from blood tests in patients with positive COVID-19 polymerase chain reaction test and with ground-glass opacity on lung tomography. Patients were divided into two groups as those who died (non-survivors) and those who were discharged (survivors)during the intensive care follow-ups. Results: In our study, in 48 patients who died during follow-up, the indexes of AISI, other inflamatuar paramaters and the biochemical parameters such as troponin I, d-dimer, ferritin and procalcitonin were significantly higher than in discharged patients. Hypertension and higher AISI and ferritin levels were statistically associated with reduced survival in Cox regression analysis (Hazard ration (HR): 3.176; 95% Confident interval (CI): 1.122-8.991, p=0.03, HR: 1.114; 95% CI: 1.060-1.348, p=0.042, HR=1.072;95% CI: 1.014-1.242, p=0.011, respectively.Conclusion: Inflammation indexes derived from blood tests and acute phase reactants such as ferritin can guide us in planning the treatment strategy and risk stratification in patients with COVID-19 in intensive care follow-ups. 
  • Küçük Resim
    Öğe
    The Value of Inflammation indexes in Predicting Patency of Saphenous Vein Grafts in Patients With Coronary Artery Bypass Graft Surgery
    (Cureus Inc, 2021) Aydın, Cihan; Engin, Mesut
    Aim:Our study aimed to investigate the predictive values of inflammation markers in predicting postoperative saphenous vein graft patency in patients who underwent coronary artery bypass grafting (CABG). Method: We retrospectively analyzed 89 patients who undergone CABG, and 49 patients diagnosed with non-critical coronary artery disease (less than <= 50% stenosis) on coronary angiography were included in the study as a control group. Eighty-nine patients who underwent CABG were divided into two groups according to the presence of 50% or more stenosis in saphenous vein grafts. In these three groups of patients, neutrophil to lymphocyte ratio (NLR), derived NLR (dNLR; neutrophils/white blood cells-neutrophils), platelet to lymphocyte ratio (PLR), lymphocyte to monocyte ratio (LMR), systemic inflammation response index (SIRI; neutrophils x monocytes/lymphocytes), systemic inflammation index (SII; platelet x neutrophil/lymphocyte), and the aggregate index of systemic inflammation (AISI; neutrophil x platelet x monocyte/lymphocyte ratio) were calculated from blood LesLs. The primary endpoint was more than 50% of saphenous vein stenosis or occlusion, and the aim is to predict this saphenous vein graft disease by inflammation indexes. Results: The groups were similar in terms of the frequency of stroke, diabetes mellitus, and chronic obstructive pulmonary disease. The frequency of heart failure and hypertension was higher in group 2 (p=0.045, p=0.005), respectively. Multivariate logistic regression analysis showed that LMR and NLR levels were independent predictors of saphenous vein graft disease (SVGD; OR: 0.896; 95%CI: 0.465-0.957; P<0.001) , (OR: 0.592; 95%CI: 0.450-0.875; P=0.034, respectively).The cut-off value of the LMR <2.625 was associated with 78.4% sensitivity and 78% specificity to predict saphenous vein graft disease in patients with CABG. Conclusion: LMR and NLR may be useful predictors for SVGD.