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    Pacemaker Leads Extraction after Pocket Infection with Abdominal Vena Cava and Common Iliac Vein Thrombosis
    (Coll Physicians & Surgeons Pakistan, 2022) Aydın, Cihan; Alpsoy, Şeref; Gür, Demet Özkaraman; Efe, Muhammed Mucip; Gürkan, Selami
    [No Abstract Available]
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    Serum chromogranin A levels are associated with the SYNTAX score in coronary artery disease
    (Assoc Medica Brasileira, 2023) Celikkol, Aliye; Demirkiran, Aykut; Aydin, Cihan; Akyuz, Aydin; Kaplangoray, Mustafa; Yilmaz, Ahsen; Efe, Muhammed Mucip
    OBJECTIVE: In this article, we investigated the association of chromogranin A with coronary artery disease.METHODS: Biochemical parameters and chromogranin A levels obtained from peripheral blood samples during coronary angiography were analyzed in 90 patients. Patients were classified into two groups, namely, SYNergy between PCI with TAXUS and Cardiac Surgery score >= 1 (n=45) and SYNergy between PCI with TAXUS and Cardiac Surgery score=0 (n=45). This is a cross-sectional, prospective study. RESULTS: Serum chromogranin A levels were significantly higher in the group with SYNergy between PCI with TAXUS and Cardiac Surgery score >= 1 compared to the group with SYNergy between PCI with TAXUS and Cardiac Surgery score=0 (1381.5 +/- 418.9 ng/mL and 1121.2 +/- 290.7 ng/mL, respectively; p=0.002). Serum chromogranin A levels were correlated with SYNergy between PCI with TAXUS and Cardiac Surgery score (r=0.556, p<0.04). ROC analysis showed that the area under the curve for serum chromogranin A levels was 0.687 (p=0.007), and the best cutoff value of 1,131 ng/mL had a sensitivity of 67% and a specificity of 65% for the prediction of coronary artery disease.CONCLUSION: Serum chromogranin A levels were increased in coronary artery disease patients with SYNergy between PCI with TAXUS and Cardiac Surgery score >= 1. Increasing serum chromogranin A levels are proportional to the SYNergy between PCI with TAXUS and Cardiac Surgery score.KEYWORDS: Chromogranin A. Coronary artery disease. Hypertension.