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Öğe Evaluation of epicardial adipose tissue and carotid intima-media thickness as a marker of atherosclerosis in patients with inflammatory bowel disease(ARAN Ediciones S.A., 2021) Ekmen, Nergiz; Can, G.; Yozgat, A.; Can, Hamit; Bayraktar, M.F.; Demirkol, MuhammetE.; Sasani, HadiBackground and aim: this study aimed to compare carotid intima media (CIMT) and epicardial adipose tissue (EAT) measurements, which are considered as markers for the detection of early atherosclerosis in healthy controls and inflammatory bowel disease (IBD) cases. Methods: a total of 60 IBD patients (25 Crohn’s disease and 35 ulcerative colitis) and 60 healthy patients (as a control group) were included in the study. The measurements of CIMT and EAT were performed using echocardiography and ultrasonography, respectively. Statistical analysis was used to determine the relationship between the parameters. Results: the thickness of bilateral (right and left) CIMT and EAT were significantly higher in IBD than in the control group (p < 0.05). There was a positive correlation between EAT and bilateral (right and left) CIMT in IBD patients (p < 0.05). Conclusion: IBD is associated with an increased thickness of EAT and CIMT. Chronic inflammation in IBD may increase the risk of atherosclerotic heart disease. Thus, only measuring the thickness of EAT and CIMT can be used as an objective, easy, simple, affordable, non-invasive and accessible assessment method in order to screen for this risk. © Copyright 2021. SEPD y © ARÁN EDICIONES, S.L.Öğe Is there any link between atrial arrhythmias and inflammatory bowel disease?(Wolters Kluwer Medknow Publications, 2021) Can, G.; Ekmen, Nergiz; Can, Hamit; Bayraktar, M.F.; Demirkol, MuhammetE.; Kayhan, M.A.; Sasani, HadiBackground: Inflammation plays an important role in the development of cardiovascular disease, including atherosclerosis and arrhythmia. The aim of this study was to evaluate atrial conduction times (ACTs) in patients with inflammatory bowel disease (IBD) in which systemic chronic inflammation is evident. Methods: In this cross-sectional, prospective, single-center study, 79 IBD patients (51 ulcerative colitis; 28 Crohn's disease) and 70 healthy controls were included. Atrial electromechanical properties were measured by recording simultaneous surface electrocardiography (ECG) with transthoracic echocardiography (ECHO) and tissue Doppler imaging methods. The relationship between age, disease duration, and ACT was evaluated. Results: There were significantly increased conduction durations of lateral-PA (time interval from the onset of the P-wave on surface ECG to the beginning of the late diastolic wave), septal-PA, tricuspid-PA, and interatrial-electromechanical delay (IA-EMD), right intraatrial EMD, and left intraatrial (LI-EMD) durations in IBD patients (P < 0.001). In IBD patients, there was a positive correlation with age, lateral PA, septal PA, tricuspid PA, IA-EMD, and LI-EMD (P < 0.05). A positive correlation was found between disease duration and only lateral PA and tricuspid PA (P < 0.05). Conclusion: In IBD patients, prolonged ACT consists a potential risk for severe atrial arrhythmias. ECG and ECHO screening can be useful in identifying risk groups in IBD patients and taking precautions for future cardiac complications. © 2021 Saudi Journal of Gastroenterology Published by Wolters Kluwer - Medknow.Öğe Presence of Neospora caninum DNA of Wild Birds from Turkey(NLM (Medline), 2021) Karakavuk, Muhammet; Can, Hamit; Aldemir, D.; Döndüren, Ö.; Karakavuk, T.; Karakavuk, E.; Döşkaya, M.; Muz, Mustafa NecatiOBJECTIVE: Neospora caninum is a protozoon parasite that has a worldwide distribution and mainly causes abortion in cattle and current serological evidence shows that the disease may be also zoonotic. Wild birds play a role as a reservoir of the disease in nature. The study aimed to determine the prensence of N. caninum in wild birds. METHODS: In this study, the presence of neosporosis in wild birds (n=55) including 22 different species found in the western side of Turkey, was investigated by polymerase chain reaction (PCR). In addition, PCR positive samples were confirmed by sequencing, BLAST, and phylogenetic analysis using MEGA7. RESULTS: Obtained results showed that the presence of N. caninum DNA was 5.45% (3/55) in brain-heart homogenates wild birds. The bird species which were found positive for N. caninum were little owl (Athene noctua), common buzzard (Buteo buteo), and little tern (Sternula albifrons). According to phylogenetic analysis and BLAST, all samples were compatible with reference N. caninum isolates. CONCLUSION: To the best of authors' knowledge, this is the first study detecting N. caninum in little tern. In future studies, it may be interesting to investigate the prevalence of N. caninum in other wild animals to elucidate the transmission properties.Amaç: Neospora caninum, dünya çapında dağılım gösteren ve esas olarak sığırlarda düşüklere neden olan protozoon bir parazittir ve güncel serolojik kanıtlar hastalığın zoonotik olabileceğini göstermektedir. Yabani kuşlar, doğada hastalığın rezervuarı olarak rol oynamaktadır. Çalışma, yabani kuşlarda N. caninum varlığının belirlenmesini amaçladı. Yöntemler: Bu çalışmada, Türkiye’nin batısındaki 22 farklı yabani kuşta (n=55) neosporosis varlığı polimeraz zincir reaksiyon (PZR) ile araştırılmıştır. Ek olarak, PZR pozitif örnekler sekanslanarak MEGA7 kullanılarak BLAST ve filogenetik analiz ile doğrulanmıştır. Bulgular: Elde edilen sonuçlara göre, yabani kuşların beyin-kalp homojenatlarının %5,45’inde (3/55) N. caninum DNA’sı saptanmıştır. Kukumav (Athene noctua), bayağı şahin (Buteo buteo) ve küçük sumru (Sternula albifrons) N. caninum pozitif bulunan kuş türleridir. Filogenetik analiz ve BLAST sonuçlarına göre, tüm örnekler referans N. caninum izolatları ile uyumlu olarak tespit edilmiştir. Sonuç: Yazarların bildiği kadarıyla bu çalışma, küçük sumruda N. caninum tespit eden ilk çalışmadır. Gelecekteki çalışmalarda N. caninum bulaşma özelliklerini aydınlatmak amacıyla diğer vahşi hayvanlarda prevalansın araştırılması faydalı olabilir. Anahtar Kelimeler: Küçük sumru, Neospora caninum, PZR, Türkiye, vahşi kuşlar.Öğe The effect of the Trans-Anatolian Natural Gas Pipeline Project (TANAP) on industrial production in Turkey(Emerald Group Publishing Ltd, 2017) Yıldırım, Durmuş Çağrı; Erdoğan, Seyfettin; Yıldırım, Seda; Can, HamitPurpose - The purpose of this study is to investigate the effect of the Trans-Anatolian Natural Gas Pipeline Project (TANAP) on industrial production in Turkey. The TANAP is a project which ensures the security of the country's natural gas supply and encourages a decrease in energy prices. So, this study investigates TANAP's efforts to decrease gas prices, as well as the effects of gas prices on industrial production. Design/methodology/approach - The data include gas prices and industrial production index series. Gas prices are approached for industrial users (nonresidential) in Turkey and industrial production index series have been discussed for whole industries. The Johansen cointegration method has been used to analyze the data, spanning the period from 2005M01 to 2015M11. Findings - Results indicate that the decrease in the energy prices has a positive effect on the industrial production index, which is accepted as a basic sign of economic growth. Accordingly, it has been proved that gas priced had a significant effect on industrial production in Turkish economy during the respective periods. Research limitations/implications - This study has supported the argument that TANAP helps to decrease gas prices in Turkey. It can be said that a decrease in gas price is expected to have positive effect on industrial production in the long-term. Originality/value - The present study shows that projects such as TANAP can help gas importing countries like Turkey to decrease gas prices and increase industrial production. In this context, this study supports projects that decreasing gas prices for energy importing countries in the long term.Öğe The molecular and serological investigation of Feline immunodeficiency virus and Feline leukemia virus in stray cats of Western Turkey(Elsevier Ltd, 2021) Muz, Dilek; Can, Hamit; Karakavuk, Muhammet; Döşkaya, M.; Özdemir, H.G.; Değirmenci Döşkaya, A.; Muz, Mustafa NecatiThis study aimed to investigate the Feline immunodeficiency virus (FIV) / Feline leukemia virus (FeLV) infection prevalence among looking healthy stray cats in Western Turkey by serologic and molecular-based tests. A total of 1008 blood samples from the stray cats were used in this study. All samples were tested for FIV antibodies / proviral DNA and FeLV antibodies / antigens / proviral DNA. The genetic characterization and phylogenetic analysis of FeLV and FIV were carried out in this study. These cats also tested for Leishmaniasis and Toxoplasmosis previously. FIV Ab and proviral DNA detected in 25.2 % and 25.5 % of samples, respectively. FeLV Ab, Ag, proviral DNA positivity was in 45.2 %, in 3.3 %, in 69.7 %, respectively. The molecular detection and phylogenetic analysis of the current FeLV pol gene and FIV gag gene performed. The molecular characterization for the pol gene of FeLV (enFeLV and exFeLV) among Turkey's cat population was reported for the first time. The exFeLV pol sequences closer to the FeLV-A genotype, and the enFeLV pol sequences overlapped with other enFeLV. The current FIV gag sequences were clustered within the subtypes A, B, and C. The findings revealed FeLV subtype A and FIV subtype-A, subtype-B, subtype-C circulate among Turkish stray cats. Single and multiple co-infection positivity was found higher compared to previous reports. © 2021 Elsevier LtdÖğe The Relation Between the Migration, Population Aging, Labor Force Productivity and Economic Growth: An Analysis for Bulgaria(Int Organization Center Acad Research, 2018) Terziev, Venelin; Can, HamitIn this study, the relationship between population, elderly population and economic growth is analyzed theoretically, taking into account the demographic change of the Bulgarian population and the more aging phenomenon. Thus, the change in the age structure of the Bulgarian population was investigated and the factors affecting the growth of the relationship between economic growth were investigated. Developed countries are trying to solve the problem of low population growth with migration. Developed countries with younger populations, such as the European Union, also allow dwellings in some periods to dampen the population and prevent the resulting loss of employment. According to a report published by the EU Statistical Institute (Eurostat), it is stated that the number of the population working in the European Union will decrease by an average of 50 million in 2060. When the current migration rate is taken into account, it is predicted that by 2060 the number of people working in European Union countries will be 110 million people less than today's number. Migration in the demographic development of the European Union has a great proposition. If a qualified migration flow is provided, it is foreseen that the deficiencies that will arise in the European Union employment market in the coming years will be eliminated. In this study, attempts were made to determine the size of the changes taking place in the country's economy, depending on the livelihoods in Bulgaria.
