Yazar "Callioglu, Nihal" seçeneğine göre listele

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    Inflammatory markers in systemic immune-inflammatory index and inflammatory response index to predict early pregnancy loss
    (Saudi Med J, 2024) Callioglu, Nihal; Gul, Derya K.; Arslan, Ilke O.; Geyikoglu, Ipek; Demircivi, Erguel
    Objectives: To uncover the predictive value of systemic immune-inflammatory index (SII) and systemic inflammatory response index (SIRI) on early pregnancy loss. Methods: A total of 535 individuals were enrolled in this retrospective analysis. The early pregnancy losses (EPL) group included patients between 18-35 years old who experienced EPL. The control group comprised healthy pregnant women who gave birth at >= 37 weeks. Results: The EPL group had significantly lower plateletcrit (p=0.04), platelet distribution width (PDW, p<0.0001), and RDW (p<0.0001) and higher monocyte (p<0.0001) and SIRI (p<0.0001) values than the control group. The hemoglobin, white blood cells, platelet count, neutrophil count, lymphocyte count, mean platelet volume, neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), monocyte-to-lymphocyte ratio (MLR), and SII values were not significantly different between the EPL and control groups (p>0.05). The cut-off value for the SIRI that offers the best sensitivity/specificity balance was 1.48 (sensitivity of 63%; specificity of 63%) in the receiver operating characteristics curve. Among the inflammatory parameters for predicting EPL, PDW had highest specificity (84%), and RDW had the highest sensitivity (80%). Conclusion: This study provides compelling evidence that various inflammatory pathways may significantly contribute to EPL pathogenesis. Moreover, our findings suggest that SIRI could be a more effective marker than NLR, PLR, MLR, and SII in predicting EPL in an ongoing pregnancy, thereby potentially revolutionizing early pregnancy loss diagnostics.
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    The effect of informing the patient about the procedure with video imaging before office hysteroscopy on pain
    (Wiley, 2023) Callioglu, Nihal; Gul, Derya Kanza; Aslan, Ilke Ozer; Tunca, Aysun Fendal; Kasim, Kardelen Basli; Akay, Burcu; Uysal, Elif
    Objective: To evaluate the effect of informing patients undergoing diagnostic office hysteroscopy via a video 24 h before the procedure and determine the changes in pain scores, channel transit time, the degree of difficulty of the procedure, and physiological parameters. Design: Single-blind randomized controlled trial. Setting: The study was conducted between September 1, 2021 and April 1, 2022 at the University of Health Sciences Bakirkoy Dr. Sadi Konuk Training and Research Hospital. Participants: A total of 134 patients aged 18-65 years who needed diagnostic office hysteroscopy. Interventions: Participants were randomized into two groups, the standard information group (Group 1: controls), and the video information + standard information group (Group 2). After office hysteroscopy, a visual analog scale (VAS) and Likert scale were used to assess pain and the degree of difficulty of the procedure, respectively. Physiological parameters were evaluated before and after the procedure. Main Outcome Measure: To determine the effect of video-based multimedia information administered 24 h before office hysteroscopy on post-procedure pain. Results: The mean VAS score of the group that watched the training video (3.02 +/- 1.88) was significantly lower than the control group (4.72 +/- 2.54) who did not watch the training video (p < 0.001). The mean cervical channel transit time in seconds (sec) during the procedure was found to be significantly higher in the control group (21.57 +/- 15.10 s) than in the video-watching group (p = 0.011). There was no significant difference between the groups in terms of physiological parameters and the degree of ease of the procedure. Conclusion: Our study has shown that informing patients in a pre-procedure video is an effective approach that shortens the duration of the channel transit time and reduces pain.