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Öğe Evaluation of the incidence of anomaly in fetus and neonates of prenatal aneuploidy screening(Bayrakol Medical Publisher, 2024) Demir, Salih; Aslan, Mustafa Torehan; Aslan, Ilke OzerAim: Our study aimed to investigate the frequency of anomalies and related maternal and neonatal outcomes in pregnant women who were admitted in our clinic in the last five years and underwent prenatal aneuploidy screening. Materials and Methods: The prenatal fetal aneuploidy screening results of the pregnant women who participated in the study, the pregnant and maternal outcomes of the pregnant women who underwent amniocentesis according to these results, and the detection rates of chromosomal aneuploidy in infants were retrospectively analyzed. Results: According to the first -trimester screening test, 22.4% of the cases (n=121); According to the second -trimester screening test, 11.8% (n=6) of the patients were found to be at high risk for chromosomal aneuploidy. Amniocentesis was recommended to 199 participating in the study, and 17.6% (n=35) of these cases were accepted. Chromosomal aneuploidy was found in 1.8% (n=3) of those who underwent amniocentesis. Two pregnancies with aneuploidy were terminated at the request of the families. The anxiety levels of the pregnant women who had prenatal screening tests were higher in the studies. Discussion: Fetal aneuploidy screening tests may give false positive results at high rates, adversely affecting maternal anxiety and, thus, pregnancy outcomes. To increase the prenatal diagnosis rates cost-effectively, it is helpful to perform combined tests to increase the sensitivity or more sensitive tests are needed.Öğe Is it possible to predict morbidities in neonates born to mothers with immune thrombocytopenic purpura?: A retrospective cross-sectional study(Lippincott Williams & Wilkins, 2024) Aslan, Mustafa Torehan; Ince, Zeynep; Bilgin, Leyla; Isguder, Cigdem Kunt; Coban, AsumanImmune thrombocytopenic purpura (ITP) comprises similar to 1% to 4% of thrombocytopenia cases during pregnancy. Factors predicting neonatal thrombocytopenia and associated morbidities due to maternal ITP are unclear. The present study aimed to assess the neonatal outcomes of pregnant women with ITP. Fifty-five pregnant women with ITP and their babies, born between January/2013 and April/2021, were retrospectively reviewed. Maternal and neonatal thrombocytopenia cases other than ITP were excluded from the study. Physical examination, blood count, and cranial/abdominal ultrasonography findings of the newborns were recorded. Neonatal thrombocytopenia was defined as a platelet count < 150 x 10(9)/L. Relationship between neonatal thrombocytopenia and maternal factors was investigated. Thrombocytopenia was detected in 17/55 babies (30.9%), and 8/17 (47.1%) had symptoms of bleeding, all but one being mild bleeding. There was a significant correlation between neonatal platelet counts of < 100 x 10(9)/L and maternal splenectomy history. Incidence of moderate and severe thrombocytopenia was higher (statistically insignificant) in neonates of mothers with ITP. No significant correlation was determined between maternal and neonatal platelet counts. There was a weak insignificant correlation between platelet counts of neonates of mothers with or without thrombocytopenia. A significant correlation was found between the presence of splenectomy before delivery in the mother and a platelet count of < 100 x 10(9)/L in the neonate. Moderate and severe thrombocytopenia was higher in neonates of mothers diagnosed with ITP before pregnancy and needed treatment during pregnancy and/or delivery, but the difference was insignificant. Close follow-up of babies born to mothers with ITP after birth is crucial since there is no significant prediction criterion for developing neonatal thrombocytopenia and associated morbidities.Öğe Retrospective evaluation of children and adolescents admitted to the pediatric intensive care unit due to suicide attempts(Bayrakol Medical Publisher, 2024) Akin, Asli; Aslan, Mustafa Torehan; Samanci, NedimAim: Suicide is a public health problem that, although not common in childhood, becomes increasingly common in adolescence. Pediatricians primarily investigate and recognize these risk factors and prevent and treat suicidal behavior by communicating with other specialties. This study aimed to determine the sociodemographic characteristics, factors leading to suicide, and suicide methods of patients who were followed up in the Pediatric Intensive Care Unit due to suicide attempts and to be able to take preventive approaches. Material and Methods: The study included 45 patients between the ages of 10 and 18 who attempted suicide between January 2019 and January 2022 and were admitted to the Pediatric Intensive Care Unit. In the study, the patients were retrospectively evaluated based on sociodemographic characteristics, nature of the suicide attempt, their psychopathology status chronic disease status. Results: The average age of 45 cases included in the study was 15.31 +/- 1.61 years. A statistically significant relationship was found between previous suicide attempts, psychiatric illness history, and psychiatry referrals. A statistically significant association was found between non -suicidal self -harm behavior and psychiatric disease history, psychopathology status, earlier referral to psychiatry, and psychiatric check-ups after a suicide attempt. Discussion: Suicide remains a serious cause of death worldwide. Not all suicides are preventable, but a systematic approach to suicide risk assessment can enable healthcare providers to identify and manage patients at risk for suicide. Considering the increasing incidence of suicide, especially in adolescence, comprehensive suicide risk assessment should be one of the pediatricians' primary and critical duties.Öğe THE DETERMINANTS IN THE MANAGEMENT OF PREGNANCIES COMPLICATED WITH IMMUNE THROMBOCYTOPENIA (vol 86, pg 295, 2023)(Istanbul Univ, Fac Medicine, Publ Off, 2024) Kunt Isguder, Cigdem; Sarac Sivrikoz, Tugba; Akin, Mehtap; Aslan, Mustafa Torehan; Selcuk Uygur, Lutfiye; Birol Ince, Sule; Kalelioglu, Ibrahim[Abstract Not Available]