Yazar "Aktug, Eray" seçeneğine göre listele

Listeleniyor 1 - 3 / 3
  • Küçük Resim Yok
    Öğe
    Effect of fermented concentrated potato protein on milk yield and fertility parameters in dairy cows in the prepartum and postpartum periods
    (Sivar-Soc Italiana Veterinari Animali Reddito, 2023) Aktug, Eray; Baytok, Erol; Turkmenoglu, Burcin
    This study aims to determine the effects of fermented concentrated potato protein (FCPP) which showed very high levels of indole acetic acid (IAA) on milk yield, fertility, and level of insulin-like growth factor 1 (IGF-1) parameters in pregnant dairy cows and pregnant heifers. In total, sixty Holstein cattle were enrolled in the study. The animals were divided into three groups, as control group (n=20), 25 g FCPP group (n=20), and 50 g FCPP group (n=20). Besides, these main groups were also divided into two sub-groups, as primiparous (n=10) and multiparous cows (n=10). Oral administration of FCPP started two weeks (14 +/- 4 days) before expected parturition and continued until postpartum day 100. The affinity of IAA found in FCPP pellets to 5HT1 and JAK2 receptors, which is thought to be related to IGF-1 release, was determined by the molecular docking method that receptor affinities were found as -5.8637 kcal/mol and -4.3857 kcal/mol, respectively. Blood IGF-1 profile was followed at 7 different time points throughout the study. It was detected that the IGF-1 concentrations have significant difference in terms of both time and groups (P<0.05). Furthermore, there was a significant difference in interaction of time and parity (P<0.05). The results showed that average and total 100-day milk yield was not affected by FCCP supplementation (P>0.05). FCPP supplementation generally has improved the mathematical data of fertility parameters, but no statistical significance was detected except for calving-conception interval. It was found that calving-conception interval reduce by 16.8% in primiparous cows supplemented with 25 g FCPP. The pregnancy rates in control, 25 g and 50 g FCPP were found as 72.2 %, 78.9 % and 88.9 %, respectively (P>0.05). This study has concluded that fermented concentrated potato protein (which has indole acetic acid-indole compounds) may improve the productivity of dairy cows supplemented in transition period and it has suggested that further research must be done for its usage and beneficial effects in dairy cows.
  • Küçük Resim Yok
    Öğe
    Mefepronic acid, a PPAR agonist, is inefficient on reproductive performance of ewes in both early and late postpartum period
    (Sivar-Soc Italiana Veterinari Animali Reddito, 2023) Kutlu, Metehan; Dogan, Halef; Aktug, Eray
    The liver is a dynamic organ that plays critical roles in many physiological processes. In farm animals, supporting the liver reduces postpartum metabolic diseases and loss of reproductive and milk yield in the transition period. The aim of this study is to investigate the effects of mefepronic acid (2-methyl-2-phenoxy propionic acid) injection on reproductive performance parameters with short-term progesterone administration in early and late postpartum period Hungarian Merino ewes during the non-breeding season. In the study, 89 adult ewes in the early (n=45) and late (n=44) postpartum (pp) period were used in the study. Control and treatment (MA) groups were formed separately for each pp period. Following insertion of a vaginal sponge containing 60 mg medroxyprogesterone acetate for 7 days, PMSG 500 IU was injected intramuscularly (day 7) to all ewes. In treatment groups (Early MA and Late MA), 10 mg/kg mefepronic acid (Hepagen((R)), Fatro Gunesli) was injected (day 7), and remaining ewes consisted of control groups (Early Control and Late Control). The estrus signs of the ewes were followed and they were handmated (ewe: ram=5:1). Pregnancies were determined with transabdominal real time B-Mode ultrasonography with convex probe (3.5 MHz) on day 45 post-mating. There were no statistical differences in estrus rate, pregnancy rate, lambing rate and litter size at 1st service, 2nd service and overall services in early and late pp groups. According to results of this study, administration of mefepronic acid to ewes in the early and late pp period had no increasing effect on reproductive parameters. However, further studies investigating the survival of embryos and prostaglandin metabolism are needed to determine the efficacy of mefepronic acid in ewes.
  • Küçük Resim Yok
    Öğe
    Mefepronic acid, a PPAR agonist, is inefficient on reproductive performance of ewes in both early and late postpartum period
    (Massimo Morgante, 2023) Kutlu, Metehan; Dogan, Halef; Aktug, Eray
    The liver is a dynamic organ that plays critical roles in many physiological processes. In farm animals, supporting the liver reduces postpartum metabolic diseases and loss of reproductive and milk yield in the transition period. The aim of this study is to investigate the effects of mefepronic acid (2-methyl-2-phenoxy propionic acid) injection on reproductive performance parameters with short-term progesterone administration in early and late postpartum period Hungarian Merino ewes during the non-breeding season. In the study, 89 adult ewes in the early (n=45) and late (n=44) postpartum (pp) period were used in the study. Control and treatment (MA) groups were formed separately for each pp period. Following insertion of a vaginal sponge containing 60 mg medroxyprogesterone acetate for 7 days, PMSG 500 IU was injected intramuscularly (day 7) to all ewes. In treatment groups (Early MA and Late MA), 10 mg/kg mefepronic acid (Hepagen®, Fatro Günesli) was injected (day 7), and remaining ewes consisted of control groups (Early Control and Late Control). The estrus signs of the ewes were followed and they were hand-mated (ewe: ram=5:1). Pregnancies were determined with transabdominal real time B-Mode ultrasonography with convex probe (3.5 MHz) on day 45 post-mating. There were no statistical differences in estrus rate, pregnancy rate, lambing rate and litter size at 1st service, 2nd service and overall services in early and late pp groups. According to results of this study, administration of mefepronic acid to ewes in the early and late pp period had no increasing effect on reproductive parameters. However, further studies investigating the survival of embryos and prostaglandin metabolism are needed to determine the efficacy of mefepronic acid in ewes. © 2023, Massimo Morgante. All rights reserved.