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Öğe Comparison of the prophylactic use of ibandronate and its use in early-stage osteonecrosis in rats with steroid-induced osteonecrosis of the femoral head(2023) Çağlar, Sever; Daşçı, Mustafa Fatih; Acar, Abdurrahman; Çağlar, Aysel; Dinçel, Yaşar Mahsut; Çataltepe, AzizObjectives: The aim of this study was to investigate the effects of ibandronate before and after the onset of osteonecrosis in rats with steroid-induced osteonecrosis of the femoral head. Materials and methods: A total of 24 female Sprague-Dawley rats were used in this study. Three groups were formed with eight rats in each group. The first group was the prophylactic group that received ibandronate treatment before and after the onset of osteonecrosis (Group PT). The second group received ibandronate treatment three weeks after the development of osteonecrosis (Group TAO). The third group was the control group in which osteonecrosis was created, but only normal saline (NS) was given. At the end of the study, all rats were sacrificed, and their right femoral heads were removed, fixed with formalin, and sent for micro-computed tomography. Hematoxylin-eosin (H&E) and immunohistochemical examinations of the right femoral head sections were performed. Results: In the PT group, the trabecular thickness was significantly higher compared to those of the TAO and control groups (pÖğe What Information is Provided in Turkish Videos about Osteoporosis and Does YouTube Provide Reliable and High-quality Information: A Systematic Analysis of YouTube Videos(Galenos Publishing House, 2022) Dinçel, Yaşar Maksut; Can, Erdem; Amiry, M.; Genç, Erdinç; Çağlar, Sever; Morina, Mekkedin; Kaval, BurakObjective: This study aims to evaluate what information is given in Turkish videos about osteoporosis on YouTube and to determine the quality and reliability of the videos. Materials and Methods: The first 50 Turkish videos about osteoporosis on YouTube were evaluated in terms of quality, reliability, and information level. Two searches were conducted for related content on YouTube and two orthopedics surgeons evaluated the videos simultaneously. The Global Quality score (GQS) (1-5) and DISCERN (15-75) scoring systems were used to assess the quality of the video content. With the Osteoporosis Specific scale (1-29), it was questioned what information specifically about osteoporosis was given in the videos while the accuracy of the video source information was evaluated with the Journal of American Medical Association (JAMA) score (1-4). Descriptive data regarding the number of views, comments, likes, dislikes were recorded, as well as the upload date to YouTube and the duration of the videos. The popularity of videos was evaluated with the video power index. Results: Considering the messages given in the videos, the most frequent information was “decrease in bone mass” with 41 videos. This was followed by “osteoporosis is a risk of fracture” and “there are risk factors for osteoporosis.” The Osteoporosis Specific score was low 8.92. The mean DISCERN score was 25.020 (15-75) and the mean GQS was 1.98 (0-5), indicating low quality. The JAMA score (1-4) for which the video source was questioned showed a low level of reliability of 1.66. Videos about osteoporosis prepared by people other than healthcare professionals were more popular (82.25 vs. 56.80) (cc=0.296, p=0.037). Conclusion: The content of the videos on YouTube osteoporosis is generally inadequate or inaccurate. Higher quality and informative videos based on international guidelines can contribute to patient compliance and increase public awareness of osteoporosis. ©Copyright 2022 by the Turkish Osteoporosis Society / Turkish Journal of Osteoporosis published by Galenos Publishing House.