Çocuklarda demir eksikliğinin febril konvülziyon ile ilişkisi

Abstract

Purpose: The aim of this study was to evaluate the relationship between febrile convulsion and iron deficiency. Materials and Methods: Between January 2016 and May 2018, 94 children aged between 3 and 60 months who were admitted to the pediatric emergency department with a history of febrile seizures were included in the study. The control group consisted of 70 patients who were hospitalized for any febrile illness but had no history of seizures. Hemoglobin, hematocrit, ferritin, iron and total iron binding capacity studied from venous blood samples taken on the first day of the disease were recorded from the patient files. Results: Hemoglobin and ferritin levels were significantly lower in patients with febrile convulsion compared to the control group [11.38 (1.00), 11.19 (1.29), 11.94 (0.90) p=0.001]. In addition, hemoglobin and ferritin values of patients who were followed because of complex febrile convulsions were also found to be significantly lower than those of simple febrile convulsions. When the factors facilitating the development of febrile convulsions in the study and control groups were analyzed by logistic regression analysis, it was shown that the low ferritin level increased the risk of convulsion by 2.49 times and iron deficiency anemia increased the risk by 1.63 times. Conclusion: In the light of the data from this study, we believe that low ferritin levels may be a risk factor for the development of febrile convulsions during the course of acute febrile diseases, but prospective studies to be performed in larger series to recommend routine iron supplementation are needed.