dc.contributor.author | Ergun, Bülent | |
dc.contributor.author | Bastu, Ercan | |
dc.contributor.author | Özsürmeli, Mehmet | |
dc.contributor.author | Çelik, Cem | |
dc.date.accessioned | 2022-05-11T14:35:50Z | |
dc.date.available | 2022-05-11T14:35:50Z | |
dc.date.issued | 2012 | |
dc.identifier.issn | 0020-8868 | |
dc.identifier.uri | https://doi.org/10.9738/CC149.1 | |
dc.identifier.uri | https://hdl.handle.net/20.500.11776/8257 | |
dc.description.abstract | Abnormal uterine bleeding (AUB) is a substantial cause of ill health in women worldwide. In this study, our aim was to evaluate the effectiveness of endometrial ablation using a modified urologic resectoscope along with tranexamic acid in AUB. Sixty patients were enrolled in this study. All patients underwent resectoscopic surgery. Patients were randomly divided into two groups. Group 1 (n = 30) received 500 mg of tranexamic acid. Group 2 (n = 30) served as the control group and underwent surgery without the administration of tranexamic acid. Total pictorial blood loss assessment chart (PBAC) scores were significantly lower postoperatively (152.14 +/- 9.65 versus 6.6 +/- 0.90; P < 0.001). When stratified by the administration of tranexamic acid, the number of patients with a postoperative day 1 PBAC score <= 15 was higher in the tranexamic group (19 versus 13), whereas the number of patients with a post operative day 1 PBAC score >15 was lower in the tranexamic group (11 versus 17), but the differences were not statistically significant (P > 0.05). AUB is a complex disease that may need repeated treatments. In expert hands, the treatment rate of resectoscopic surgery seems acceptable. However, some patients may require additional interventions, like repeated surgery, hysterectomy, or a drug therapy in the long run. Introduction of tranexamic acid as a potential adjunct to rollerball endometrial ablation may present an interesting option that requires additional well-designed studies before firm conclusions can be made. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Int College Of Surgeons | en_US |
dc.identifier.doi | 10.9738/CC149.1 | |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Abnormal uterine bleeding | en_US |
dc.subject | Endometrial ablation | en_US |
dc.subject | Resectoscopic surgery | en_US |
dc.subject | Randomized-Controlled-Trial | en_US |
dc.subject | Abdominal Hysterectomy | en_US |
dc.subject | Resection | en_US |
dc.subject | Menorrhagia | en_US |
dc.subject | Outcomes | en_US |
dc.title | Tranexamic Acid: A Potential Adjunct to Resectoscopic Endometrial Ablation | en_US |
dc.type | article | en_US |
dc.relation.ispartof | International Surgery | en_US |
dc.department | Fakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kadın Hastalıkları ve Doğum Ana Bilim Dalı | en_US |
dc.authorid | 0000-0003-0810-6195 | |
dc.identifier.volume | 97 | en_US |
dc.identifier.issue | 4 | en_US |
dc.identifier.startpage | 310 | en_US |
dc.identifier.endpage | 314 | en_US |
dc.institutionauthor | Çelik, Cem | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.authorscopusid | 6602816744 | |
dc.authorscopusid | 55022842500 | |
dc.authorscopusid | 54684844400 | |
dc.authorscopusid | 24075279000 | |
dc.authorwosid | ozsurmeli, mehmet/AAA-9941-2019 | |
dc.authorwosid | Bastu, Ercan/K-5354-2017 | |
dc.identifier.wos | WOS:000313363800009 | en_US |
dc.identifier.scopus | 2-s2.0-84896535001 | en_US |
dc.identifier.pmid | 23294071 | en_US |